ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

← catalyst calendar

NCT04561518 · readout in 2,691 d

Sponsored by Alnylam Pharmaceuticals (industry) · ALNY — their whole pipeline →.

Phase

—

Status

Recruiting

Study type

Observational

Enrollment

1,500estimated

Sites

Countries

Brazil, Bulgaria, Denmark +9

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis

Date

Filed

Basis

What it is

Start

2020-11-23

actual

When the study began enrolling

Primary completion

2033-12-31

estimated

The date the last participant is measured for the primary outcome — the readout window

Study completion

2033-12-31

estimated

The whole study's end, after follow-up

First posted

2020-09-23

actual

When this record first appeared on the registry

Results posted

—

When the sponsor posted results to the registry

Record updated

2026-05-29

actual

The sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

Transthyretin-Mediated Amyloidosis
ATTR Amyloidosis

Primary outcomes

what the primary-completion date above is the date OF

Incidence of Adverse Events

measured From time of enrollment for up to 10 years

Selected Events of Interest in Patients with Hereditary Transthyretin-mediated (hATTR) or Wild-type Transthyretin-mediated (wtATTR) Amyloidosis (ATTRv Amyloidosis)

measured From 1 year prior to enrollment for up to 10 years

Health Care Provider (HCP)-Assessed Polyneuropathy (PND) Disability Score

measured Up to 11 years

HCP-Assessed Familial Amyloidotic Polyneuropathy (FAP) Score

measured Up to 11 years

HCP-Assessed Neuropathy Impairment Score (NIS)

measured Up to 11 years

HCP-Assessed Cardiomyopathy

measured Up to 11 years

HCP- Assessed Cardiopulmonary Exercise Testing (CPET) Performance

measured Up to 11 years

Norfolk Quality of Life - Diabetic Neuropathy (QOL-DN) Total Score

measured Up to 11 years

Kansas City Cardiomyopathy Questionnaire (KCCQ)

measured Up to 11 years

Rasch-built Overall Disability Scale (R-ODS)

measured Up to 11 years

Permalink · ALNY's whole pipeline · Catalyst calendar · Every registered study · What changed