Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia
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Phase
Phase 3
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
182actual
Sites
70
Countries
Austria, Belgium, Bulgaria +15
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2020-12-16 | actual | When the study began enrolling |
| Primary completion | 2023-07-19 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Aug 2027 | estimated | The whole study's end, after follow-up |
| First posted | 2020-07-29 | actual | When this record first appeared on the registry |
| Results posted | 2025-02-05 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-05-11 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Congenital Adrenal Hyperplasia
Interventions
- Drug: Crinecerfont — also filed as NBI-74788, Crenessity
- Drug: Placebo
Primary outcome
what the primary-completion date above is the date OFPercent Change From Baseline in Glucocorticoid Daily Dose at Week 24
measured Baseline, Week 24
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2021-11-30 · 7.5 MB · Prot_000.pdf
Statistical Analysis Planposted 2023-08-10 · 1.1 MB · SAP_001.pdf
Publications
- PMID 38828955 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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