A Study of AB-106 in Subjects With Advanced NSCLC Harboring ROS1 Fusion Gene
← catalyst calendarSponsored by Nuvation Bio Inc. (industry) · NUVB — their whole pipeline →.
Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
173actual
Sites
1
Country
China
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2020-07-07 | actual | When the study began enrolling |
| Primary completion | 2024-06-07 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Jun 2027 | estimated | The whole study's end, after follow-up |
| First posted | 2020-05-20 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-02-06 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Non Small Cell Lung Cancer
Intervention
- Drug: AB-106 — also filed as DS-6051b
Primary outcome
what the primary-completion date above is the date OFBest overall response (BOR) by IRC
measured 6 months
Publications
- PMID 42013573 — linked by the registry
- PMID 40179330 — linked by the registry
- PMID 38822758 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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