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Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI)

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NCT04295538

Sponsored by AbbVie (industry) · ABBV — their whole pipeline →.

Phase
Phase 2
Status
Completed
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
60actual
Sites
41
Countries
Australia, Canada, Israel +4

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2020-09-06actualWhen the study began enrolling
Primary completion2026-01-26actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-01-26actualThe whole study's end, after follow-up
First posted2020-03-04actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-02-11actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Spinal Cord Injury (SCI)

Interventions

  • Drug: Elezanumab — also filed as ABT-555
  • Drug: Placebo

Primary outcomes

what the primary-completion date above is the date OF
Upper Extremity Motor Score (UEMS)
measured 52 Weeks
Number of Participants Experiencing Adverse Events
measured Up to approximately 91 Weeks

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