9-ING-41 in Pediatric Patients With Refractory Malignancies.
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Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Why the sponsor stopped it
The decision to conclude study was made to optimize the clinical study design and protocol to further evaluate the safety profile of elraglusib (9-ING-41) in pediatric and adult patients with refractory Ewings Sarcoma.
As filed on the registry record, in the sponsor's own words.
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2020-06-05 | actual | When the study began enrolling |
| Primary completion | 2025-07-07 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-07-07 | actual | The whole study's end, after follow-up |
| First posted | 2020-01-23 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-07-17 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Refractory Cancer
- Refractory Neoplasm
- Cancer Pediatric
- Refractory Tumor
- Pediatric Cancer
- Pediatric Brain Tumor
- Neuroblastoma
- Neuroblastoma Recurrent
- Pediatric Lymphoma
- Pediatric Meningioma
- Diffuse Intrinsic Pontine Glioma
Interventions
- Drug: 9-ING-41 — also filed as 9-ING-41 COMPOUND
- Drug: Irinotecan — also filed as CPT-11
- Drug: Temozolomide — also filed as Temodar
- Drug: Cyclophosphamide — also filed as Cyclophosphamide IV
- Drug: Topotecan — also filed as Topotecan IV
Primary outcome
what the primary-completion date above is the date OFPublications
- PMID 24327518 — reports results
- PMID 27424289 — reports results
- PMID 28672195 — reports results
- PMID 29383130 — reports results
- PMID 29846250 — reports results
- PMID 31101621 — reports results
- PMID 31533931 — reports results
- PMID 31831767 — reports results
- PMID 31882719 — reports results
- PMID 28053024 — reports results
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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