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BP1001-A in Patients With Advanced or Recurrent Solid Tumors

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NCT04196257 · readout ≤ 346 d

Sponsored by Bio-Path Holdings, Inc. (industry) · BPTH — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
50estimated
Sites
4
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-08-19actualWhen the study began enrolling
Primary completionJul 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionOct 2027estimatedThe whole study's end, after follow-up
First posted2019-12-12actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-03-07actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Solid Tumor, Adult
  • Carcinoma, Ovarian Epithelial
  • Fallopian Tube Neoplasms
  • Endometrial Cancer
  • Peritoneal Cancer
  • Solid Tumor

Interventions

  • Drug: BP1001-A (Liposomal Grb2 Antisense Oligonucleotide)
  • Drug: BP1001-A (Liposomal Grb2 Antisense Oligonucleotide) with paclitaxel

Primary outcomes

what the primary-completion date above is the date OF
Identify Dose Limiting Toxicity (DLT) of BP1001-A
measured 30 days
Identify maximum tolerated dose (MTD) of BP1001-A
measured 30 days
Identify and grade Treatment-Emergent Adverse Events (TEAE) of BP1001-A
measured 30 days
Identify and grade Treatment-Emergent Adverse Events (TEAE) of BP1001-A in combination with paclitaxel
measured 30 days

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