Zephyr Valve Registry (ZEVR)
← catalyst calendarNCT04186546 · readout in 133 d
Sponsored by Pulmonx Corporation (industry) · LUNG — their whole pipeline →.
Phase
—
Status
Active, not recruiting
Study type
Observational
Enrollment
150estimated
Sites
11
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2019-11-25 | actual | When the study began enrolling |
| Primary completion | 2026-12-31 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2026-12-31 | estimated | The whole study's end, after follow-up |
| First posted | 2019-12-04 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-04-29 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Emphysema
Intervention
- Device: Zephyr Valve Procedure — also filed as Zephyr Endobronchial Valve, Endobronchial Valve, Bronchoscopic Lung Volume Reduction, BLVR
Primary outcomes
what the primary-completion date above is the date OFIncidence Rate of Pneumothorax from Baseline to 45-days post-procedure
measured Baseline to 45-days post-procedure
Incidence Rate of Serious Adverse Events (SAEs) of Interest from Baseline to 3 years post-procedure
measured Baseline to 3 years post-procedure
Publications
- PMID 27580428 — cited as background
- PMID 26650153 — cited as background
- PMID 27974713 — cited as background
- PMID 27492521 — cited as background
- PMID 26116485 — cited as background
- PMID 27999170 — cited as background
- PMID 20860505 — cited as background
- PMID 22282552 — cited as background
- PMID 27562904 — cited as background
- PMID 29787288 — cited as background
- PMID 28885054 — cited as background
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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