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Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With Advanced Malignancies

← catalyst calendar

NCT04164199

Sponsored by BeOne Medicines (industry) · ONC — their whole pipeline →.

Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
404actual
Sites
106
Countries
Australia, China, France +10

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2019-12-19actualWhen the study began enrolling
Primary completion2026-05-23actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-05-23actualThe whole study's end, after follow-up
First posted2019-11-15actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-03actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Advanced Malignancies

Interventions

  • Drug: Tislelizumab — also filed as BGB-A317
  • Drug: Pamiparib — also filed as BGB-290
  • Drug: Temozolomide
  • Drug: Sitravatinib
  • Drug: Ociperlimab — also filed as BGB-A1217
  • Drug: BAT1706
  • Drug: Fruquintinib
  • Drug: BGB-15025
  • Drug: Zanidatamab — also filed as ZW25
  • Drug: BGB-A445 — also filed as Gimistotug
  • Drug: Surzebiclimab — also filed as BGB-A425
  • Drug: Lenvatinib
  • Drug: LBL-007 — also filed as Alcestobart

Primary outcome

what the primary-completion date above is the date OF
Number of Participants with Immune-Mediated Adverse Events, Serious Adverse Events, and Adverse Events Grade 3 or Higher
measured up to 7 years

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