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Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)

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NCT04150497

Sponsored by Cellectis S.A. (industry) · CLLS — their whole pipeline →.

Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
52estimated
Sites
19
Countries
France, United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2019-10-14actualWhen the study began enrolling
Primary completion2026-06-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-06-30estimatedThe whole study's end, after follow-up
First posted2019-11-04actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-09-09actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • B-cell Acute Lymphoblastic Leukemia

Interventions

  • Biological: UCART22
  • Biological: CLLS52 — also filed as Alemtuzumab

Primary outcomes

what the primary-completion date above is the date OF
Incidence of AE/SAE/DLT [Safety and Tolerability]
measured 24 Months
Dose escalation part: Occurrence of Dose Limiting Toxicities (DLTs)
measured Up to D28 post initial UCART22 infusion

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