A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
← catalyst calendarSponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →. With New Approaches to Neuroblastoma Therapy Consortium, Innovative Therapies for Children with Cancer in Europe (ITCC).
Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
71estimated
Sites
17
Countries
Australia, Belgium, France +6
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2020-06-11 | actual | When the study began enrolling |
| Primary completion | 2022-04-13 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Aug 2026 | estimated | The whole study's end, after follow-up |
| First posted | 2019-09-26 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-04-21 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Neuroblastoma
Interventions
- Drug: LY3295668 Erbumine
- Drug: Topotecan
- Drug: Cyclophosphamide
Primary outcomes
what the primary-completion date above is the date OFNumber of Participants with Dose Limiting Toxicities (DLTs)
measured Baseline through Cycle 2 (28 Day Cycle)
Overall Response Rate (ORR): Percentage of Participants Who Achieve Complete Response (CR) or Partial Response (PR)
measured Baseline through Measured Progressive Disease (Estimated up to 5 Years)
Duration of Response (DoR)
measured Date of CR or PR to Date of Disease Progression or Death Due to Any Cause (Estimated up to 5 Years)
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