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Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

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NCT03999801 · readout ≤ 865 d

Sponsored by AbbVie (industry) · ABBV — their whole pipeline →.

Phase
Phase 2
Status
Enrolling by invitation
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
865estimated
Sites
9
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2019-05-31actualWhen the study began enrolling
Primary completionDec 2028estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionDec 2028estimatedThe whole study's end, after follow-up
First posted2019-06-27actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2024-06-17actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Neovascular Age-related Macular Degeneration
  • Wet Macular Degeneration

Intervention

  • Genetic: RGX-314

Primary outcomes

what the primary-completion date above is the date OF
Incidence of ocular adverse events and any serious adverse events in the study eye
measured 5 years inclusive of parent study
Fellow eye substudy: Incidence of ocular adverse events and any serious adverse events in the fellow eye
measured 54 weeks

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