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A Dose Escalation Study Evaluating CPI-818 in Relapsed/Refractory T-Cell Lymphoma

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NCT03952078

Sponsored by Corvus Pharmaceuticals, Inc. (industry) · CRVS — their whole pipeline →.

Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
151estimated
Sites
22
Countries
Australia, China, South Korea +1

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2019-05-03actualWhen the study began enrolling
Primary completion2026-04-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-04-30estimatedThe whole study's end, after follow-up
First posted2019-05-16actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-04-16actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • T-cell Lymphoma

Intervention

  • Drug: CPI-818

Primary outcomes

what the primary-completion date above is the date OF
Incidence, nature, and severity of adverse events following treatment with CPI 818 to establish the safety and tolerability with increasing dose
measured First dose until 30 days after treatment stop
Incidence and nature of dose limiting toxicities (DLTs) of CPI 818 to establish either the maximum tolerated dose (MTD) or the maximum administered dose (MAD) of CPI 818
measured Up to approximately 21 days after first dose

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