RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer
← catalyst calendarSponsored by Agenus Inc. (industry) · AGEN — their whole pipeline →. With GOG Foundation.
Phase
Phase 2
Status
Terminated
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
211actual
Sites
68
Countries
Brazil, Mexico, Peru +4
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Why the sponsor stopped it
Sponsor strategic decision
As filed on the registry record, in the sponsor's own words.
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2019-06-01 | actual | When the study began enrolling |
| Primary completion | 2025-03-26 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-03-26 | actual | The whole study's end, after follow-up |
| First posted | 2019-03-28 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-03-27 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Cervical Cancer
Interventions
- Drug: AGEN2034
- Drug: AGEN1884
Primary outcome
what the primary-completion date above is the date OFObjective Response Rate
measured 48 months
Publications
- PMID 21525385 — reports results
- PMID 26858122 — reports results
- PMID 27269741 — reports results
- PMID 16382236 — reports results
- PMID 28607581 — reports results
- PMID 27141885 — reports results
- PMID 26558876 — reports results
- PMID 23897982 — reports results
- PMID 21074063 — reports results
- PMID 25619164 — reports results
- PMID 28636851 — reports results
- PMID 15240681 — reports results
- PMID 18586928 — reports results
- PMID 25539810 — reports results
- PMID 20516428 — reports results
- PMID 27717298 — reports results
- PMID 19097774 — reports results
- PMID 29617360 — reports results
- PMID 28835386 — reports results
- PMID 28678668 — reports results
- PMID 27932067 — reports results
- PMID 29731394 — reports results
- PMID 29657128 — reports results
- PMID 29423118 — reports results
- PMID 25922725 — reports results
- PMID 28228726 — reports results
- PMID 26398076 — reports results
- PMID 11224527 — reports results
- PMID 23728179 — reports results
- PMID 26403783 — reports results
- PMID 28040721 — reports results
- PMID 7165009 — reports results
- PMID 34409858 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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