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A Study Evaluating Temferon in Patients With Glioblastoma & Unmethylated MGMT

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NCT03866109

Sponsored by Genenta Science (industry) · GNTA — their whole pipeline →.

Phase
Phase 1/2
Status
Terminated
Study type
Interventional
Design
Na · None · Treatment
Enrollment
25actual
Sites
3
Country
Italy

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

LVLP (pt GBM-01034) took place on 27may2026. The 2 remaining slots allocated by the protocol for the additional cohort to generate safety data prior to study Part B will not be filled. No safety concerns. Benefit-risk profile unchanged.

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2019-03-05actualWhen the study began enrolling
Primary completion2026-05-27actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-05-27actualThe whole study's end, after follow-up
First posted2019-03-07actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-11actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Glioblastoma Multiforme

Intervention

  • Drug: Temferon

Primary outcome

what the primary-completion date above is the date OF
Tolerability and safety of Temferon over the first 90 days following administration as determined by the incidence of adverse events
measured 90 days

Publications

Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.

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