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Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD

← catalyst calendar

NCT03836482 · readout ≤ 193 d

Sponsored by SeaStar Medical (industry) · ICU — their whole pipeline →. With National Heart, Lung, and Blood Institute (NHLBI), University of Michigan, Innovative BioTherapies (IBT).

Phase
Not applicable
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
20estimated
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-10-02actualWhen the study began enrolling
Primary completionFeb 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionAug 2027estimatedThe whole study's end, after follow-up
First posted2019-02-11actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-03-31actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Acute on Chronic Systolic Congestive Heart Failure
  • Cardiorenal Syndrome

Intervention

  • Device: Selective Cytopheretic Device

Primary outcomes

what the primary-completion date above is the date OF
Need for continuous IV vasopressor support
measured measured daily, at or after 4 hours after termination of daily SCD therapy
Acute myocardial infarction
measured up to 6 months following SCD treatment initiation
Mortality
measured up to 6 months following SCD treatment initiation
Percentage of subjects with reversal of WRF and increase eGFR and PCW
measured up to 6 days after initiation of SCD therapy
Percentage of subjects who no longer have severe right ventricular failure
measured up to 6 days after initiation of SCD therapy
Adverse Events
measured up to 6 days after initiation of SCD therapy

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