A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients
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Phase
Phase 3
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
407actual
Sites
87
Countries
China, Hong Kong, India +7
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2018-11-27 | actual | When the study began enrolling |
| Primary completion | 2024-06-23 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2027-02-26 | estimated | The whole study's end, after follow-up |
| First posted | 2018-10-16 | actual | When this record first appeared on the registry |
| Results posted | 2025-02-12 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-08-06 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Carcinoma, Non-Small-Cell Lung
Interventions
- Drug: Durvalumab — also filed as MEDI4736
- Other: Placebo
Primary outcome
what the primary-completion date above is the date OFProgression-Free Survival (PFS) (Modified Intent-to-Treat [mITT] Set)
measured Tumor scans performed at screening, every 8 weeks ±1 week up to 48 weeks, and then every 12 weeks ±1 week thereafter until confirmed PD. Assessed up to the DCO date 23-Jun-2024 (a maximum of approximately 2035 days)
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2023-08-28 · 5.1 MB · Prot_000.pdf
Statistical Analysis Planposted 2024-03-18 · 1.6 MB · SAP_001.pdf
Publications
- PMID 41354932 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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