Combinations of Cemiplimab (Anti-PD-1 Antibody) and Platinum-based Doublet Chemotherapy in Patients With Lung Cancer
← catalyst calendarSponsored by Regeneron Pharmaceuticals (industry) · REGN — their whole pipeline →. With Sanofi.
Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
789actual
Sites
133
Countries
Austria, China, France +15
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2018-03-06 | actual | When the study began enrolling |
| Primary completion | 2025-02-27 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-02-27 | actual | The whole study's end, after follow-up |
| First posted | 2018-01-24 | actual | When this record first appeared on the registry |
| Results posted | 2026-04-29 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-05-18 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Non-small Cell Lung Cancer
Interventions
- Drug: REGN2810 — also filed as cemiplimab
- Drug: REGN2810/chemo/ipi — also filed as cemiplimab
- Other: Chemotherapy
- Drug: Placebo
Primary outcomes
what the primary-completion date above is the date OFPart 1: Overall Survival (OS)
measured Up to a maximum of 82.2 months
Part 2: OS
measured Up to a maximum of 68.4 months
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2020-04-16 · 1.7 MB · Prot_000.pdf
Statistical Analysis Planposted 2021-01-25 · 456 KB · SAP_001.pdf
Publications
- PMID 38820979 — linked by the registry
- PMID 37348996 — linked by the registry
- PMID 37001859 — linked by the registry
- PMID 36008722 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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