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Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure Registry

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NCT03326076

Sponsored by CareDx (industry) · CDNA — their whole pipeline →.

Phase
Status
Unknown status
Study type
Observational
Enrollment
4,000estimated
Sites
72
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2018-01-23actualWhen the study began enrolling
Primary completion2025-06-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-12-31estimatedThe whole study's end, after follow-up
First posted2017-10-30actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2023-06-27actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Kidney Transplant Rejection

Interventions

  • Diagnostic test: Donor-derived cell-free DNA (AlloSure®)
  • Other: Standard care
  • Diagnostic test: Peripheral blood gene expression profiling (AlloMap Kidney)
  • Diagnostic test: Analytic platform (IBox)

Primary outcomes

what the primary-completion date above is the date OF
Interstitial fibrosis/tubular atrophy (IF/TA) quantified by Banff Working Group biopsy grade(s) at 12 months post-transplant in AlloSure® and renal allograft biopsy managed patients
measured Feb-2020
Total number of biopsies planned and performed post-transplant, including both surveillance and clinically indicated biopsies
measured Feb-2020

Publications

Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.

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