Study of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC)
← catalyst calendarSponsored by Regeneron Pharmaceuticals (industry) · REGN — their whole pipeline →. With Sanofi.
Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
712actual
Sites
192
Countries
Australia, Belarus, Brazil +21
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2017-05-29 | actual | When the study began enrolling |
| Primary completion | 2025-04-18 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-04-18 | actual | The whole study's end, after follow-up |
| First posted | 2017-03-23 | actual | When this record first appeared on the registry |
| Results posted | 2026-06-25 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-06-25 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Carcinoma，Non-Small-Cell Lung
- Lung Carcinomas, Non-Small-Cell
- Non-small-cell Lung Carcinoma
- Nonsmall Cell Lung Cancer
Interventions
- Drug: Pemetrexed
- Drug: Paclitaxel
- Drug: Gemcitabine
- Drug: Cisplatin
- Drug: Carboplatin
- Drug: cemiplimab — also filed as REGN2810, Libtayo
Primary outcomes
what the primary-completion date above is the date OFOverall Survival (OS)
measured Up to 94 months
Progression-free Survival (PFS) Per Blinded IRC
measured Up to 94 months
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2020-05-13 · 1.6 MB · Prot_000.pdf
Statistical Analysis Planposted 2020-03-16 · 474 KB · SAP_001.pdf
Publications
- PMID 41808570 — linked by the registry
- PMID 40991883 — linked by the registry
- PMID 40118215 — linked by the registry
- PMID 37591293 — linked by the registry
- PMID 36308296 — linked by the registry
- PMID 33581821 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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