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An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

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NCT02955940 · readout in 406 d

Sponsored by Incyte Corporation (industry) · INCY — their whole pipeline →.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
10actual
Sites
9
Countries
Poland, United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2016-11-30actualWhen the study began enrolling
Primary completion2027-09-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-09-30estimatedThe whole study's end, after follow-up
First posted2016-11-04estimatedWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-17actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Pancreatic Cancer
  • Colorectal Cancer (CRC)
  • Breast Cancer
  • Lung Cancer

Interventions

  • Drug: Ruxolitinib — also filed as INCB018424, Jakafi®
  • Drug: Capecitabine — also filed as Xeloda®
  • Drug: Regorafenib — also filed as Stivarga®

Primary outcome

what the primary-completion date above is the date OF
Frequency and types of adverse events and serious adverse events
measured Maximum duration of every 2 months (maximum duration of 1 month for subjects receiving regorafenib) from enrollment through 30-37 days after end of treatment up to 24 months.

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