PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis
← catalyst calendarSponsored by Edwards Lifesciences (industry) · EW — their whole pipeline →.
Phase
Not applicable
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
1,000actual
Sites
77
Countries
Australia, Canada, Japan +2
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | Mar 2016 | actual | When the study began enrolling |
| Primary completion | 2020-11-16 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Dec 2029 | estimated | The whole study's end, after follow-up |
| First posted | 2016-02-05 | estimated | When this record first appeared on the registry |
| Results posted | 2021-12-02 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-01-14 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Aortic Stenosis
Interventions
- Procedure: SAVR
- Device: SAPIEN 3 THV
Primary outcome
what the primary-completion date above is the date OFAll-cause Mortality, All Stroke, and Rehospitalization (Valve-related or Procedure-related and Including Heart Failure)
measured 1 year
Posted documents
hosted by the registry — we link, never re-serveStudy Protocol and Statistical Analysis Planposted 2018-12-01 · 19.3 MB · Prot_SAP_000.pdf
Publications
- PMID 42524810 — linked by the registry
- PMID 42508852 — linked by the registry
- PMID 42340728 — linked by the registry
- PMID 41144631 — linked by the registry
- PMID 40243974 — linked by the registry
- PMID 37874020 — linked by the registry
- PMID 36813373 — linked by the registry
- PMID 36622552 — linked by the registry
- PMID 35595203 — linked by the registry
- PMID 34139864 — linked by the registry
- PMID 34130476 — linked by the registry
- PMID 33663731 — linked by the registry
- PMID 32272848 — linked by the registry
- PMID 30883058 — linked by the registry
- PMID 28279376 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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