A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer
← catalyst calendarSponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.
Phase
Phase 3
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
453actual
Sites
231
Countries
Argentina, Austria, Brazil +18
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2014-10-03 | actual | When the study began enrolling |
| Primary completion | 2017-09-15 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Dec 2026 | estimated | The whole study's end, after follow-up |
| First posted | 2014-06-02 | estimated | When this record first appeared on the registry |
| Results posted | 2018-12-12 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-02-06 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Non Small Cell Lung Cancer
Interventions
- Drug: Abemaciclib — also filed as LY2835219
- Drug: Erlotinib
Primary outcome
what the primary-completion date above is the date OFOverall Survival (OS)
measured From Randomization Date to Date of Death from Any Cause (Up to 32 Months)
Posted documents
hosted by the registry — we link, never re-serveStudy Protocol: Protocolposted 2014-05-13 · 847 KB · Prot_001.pdf
Study Protocol: Protocol (e)posted 2016-12-20 · 1.0 MB · Prot_002.pdf
Statistical Analysis Planposted 2017-10-02 · 827 KB · SAP_000.pdf
Publications
- PMID 33194700 — linked by the registry
- PMID 26432508 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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