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Psoriasis trial readouts

registry pull 2026-08-19

Primary-completion dates that listed drug and biotech companies filed with ClinicalTrials.gov for studies in Psoriasis. They are the sponsor's own estimated windows, revised as a study runs — not announcement dates. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Upcoming readout windows

next 180 days · by month

2 studies across 2 companies, in the next 180 days.

October 2026 1

TickerNameStudyPhaseStatusPrimary completionReadout inUpdated
OGNOrganon and CoTapinarof for the Treatment of Plaque Psoriasis in Pediatric SubjectsNCT05172726Adverse Events (AEs) and Serious Adverse Events (SAEs)Phase 3Active, not recruitingOct 2026≤ 72 d2026-04-17

January 2027 1

TickerNameStudyPhaseStatusPrimary completionReadout inUpdated
BMYBristol-Myers SquibbA Study on the Safety of Deucravacitinib Exposure in Pregnant Women and Their OffspringNCT06710470observationalNumber of infants born with Major Congenital Malformations (MCMs)Active, not recruiting2027-01-31in 164 d2024-11-29

Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.

Every registered study in Psoriasis

most recently updated first

346 studies match. Showing the first 100 of 346 studies — page through, or narrow the filters.

TickerNameMarket capStudyPhaseStatusInterventionsConditionsEnrollmentStartPrimary completionReadout inUpdated
BMYBristol-Myers Squibb$134.9BA Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque PsoriasisNCT04772079Observed average concentration at steady state for deucravacitinib at Week 2Phase 3RecruitingDrug: Deucravacitinib · Other: Placebo matching deucravacitinibPlaque Psoriasis1532021-03-232029-01-01in 865 d2026-08-18
LLYDICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company$1.15TA Study of LY4100511 (DC-853) in Adult Participants With Moderate-to-Severe Plaque PsoriasisNCT06602219results2026-08-18Percentage of Participants Achieving ≥75% Reduction From Baseline in Psoriasis Area and Severity Index (PASI-75) at Week 12 (LY4100511 Versus Placebo)Phase 2CompletedDrug: LY4100511, PlaceboPlaque Psoriasis2222024-10-252025-07-24actual2026-08-18
ORKAOruka Therapeutics, Inc.$7.5BDose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque PsoriasisNCT07290569Proportion of Participants Achieving 100% Reduction in PASI Score at Week 16Phase 2Active, not recruitingDrug: ORKA-001 · Other: PlaceboPlaque Psoriasis1602025-12-03Jun 2027≤ 314 d2026-08-17
SNGXSoligenix$9MTopical SGX302 for Mild-to-Moderate PsoriasisNCT05442190Number of patients that achieve a 0 or 1 score using the 5-point Investigator's Global Assessment scalePhase 2CompletedDrug: HypericinPsoriasis, Plaque Psoriasis, Psoriasis Vulgaris152022-12-142025-10-22actual2026-08-13
BMYBristol-Myers Squibb$134.9BA Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque PsoriasisNCT06979453Number of participants achieving at least 75% improvement in Psoriasis Area and Severity Index (PASI 75)Phase 3RecruitingDrug: Deucravacitinib · Other: PlaceboPlaque Psoriasis3662025-12-032029-10-12in 1,149 d2026-08-11
ALMSAlumis Inc$2.1BA Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque PsoriasisNCT06586112To determine whether ESK-001 reduces the severity of psoriasis by 75% (using the PASI) or by at least 2 points (using sPGA score) compared to placeboPhase 3CompletedDrug: Envudeucitinib, Apremilast, PlaceboPlaque Psoriasis9122024-07-252025-09-19actual2026-08-10
ALMSAlumis Inc$2.1BA Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001NCT06588738To determine whether ESK-001 reduces the severity of psoriasis by 75% (using the PASI) or by at least 2 points (using sPGA score) compared to placeboPhase 3CompletedDrug: Envudeucitinib, Placebo, ApremilastPlaque Psoriasis8622024-08-202025-09-23actual2026-08-10
ORKAOruka Therapeutics, Inc.$7.5BDose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque PsoriasisNCT07474792Proportion of Participants Achieving 100% Reduction in PASI Score at Week 16Phase 2RecruitingDrug: ORKA-002 · Other: PlaceboPlaque Psoriasis1602026-03-19Oct 2027≤ 437 d2026-08-10
ARQTArcutis Biotherapeutics, Inc.$3.3BMaximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-216)NCT04746911results2026-08-07Plasma Concentration of Roflumilast Following Daily Application of Roflumilast Cream 0.3%Phase 2CompletedDrug: ARQ-151 cream 0.3%Psoriasis, Plaque Psoriasis102021-03-012022-05-11actual2026-08-07
ABBVAbbVie$457.5BStudy to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque PsoriasisNCT07039110observationalProportion of participants achieving a Dermatology Life Quality Index (DLQI) score of 0 or 1RecruitingPlaque Psoriasis7002025-09-09Mar 2028≤ 589 d2026-08-05
ORKAOruka Therapeutics, Inc.$7.5BAn Open-Label Extension Study of ORKA-001 in Participants With Plaque PsoriasisNCT07449702Incidence of Treatment-emergent Adverse Events (TEAEs), Treatment-emergent Serious Adverse Events (TESAEs), and TEAEs of Special Interest (TEAESIs)Phase 2RecruitingDrug: ORKA-001Plaque Psoriasis2402026-02-23May 2030≤ 1,380 d2026-08-05
ALMSAlumis Inc$2.1BOpen-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque PsoriasisNCT05739435To assess the safety and tolerability of long-term ESK-001 treatmentPhase 2Active, not recruitingDrug: envudeucitinibPlaque Psoriasis1652023-01-172027-12-01in 468 d2026-07-28
BMYBristol-Myers Squibb$134.9BLong-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)NCT07116967Composite cardiovascular adjudicated 3-point major adverse cardiovascular event (MACE) plus coronary revascularizationPhase 3RecruitingDrug: Deucravacitinib, UstekinumabPlaque Psoriasis3,0402025-09-222031-01-16in 1,610 d2026-07-23
AMGNAmgen$229.9BA Study to Assess the Efficacy and Safety of Apremilast in Japanese Pediatric Participants With Moderate to Severe Plaque PsoriasisNCT05565560Achievement of a static Physician Global Assessment (sPGA) score of clear (0) or almost clear (1) with at least 2 points reduction from baseline at Week 16Phase 3Active, not recruitingDrug: ApremilastPlaque Psoriasis172023-01-252025-11-20actual2026-07-15
ORKAOruka Therapeutics, Inc.$7.5BORKA-001 Versus Placebo in Patients With Moderate-to-Severe Plaque PsoriasisNCT07090330Proportion of Participants Achieving 100% Reduction in PASI Score at Week 16Phase 2Active, not recruitingDrug: ORKA-001 Induction Dose, ORKA-001 Maintenance Dose · Other: PlaceboPlaque Psoriasis802025-07-182026-03-25actual2026-07-01
LLYEli Lilly and Company$1.15TIxekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or OverweightNCT06588283Percentage of Participants Who Simultaneously Achieved Psoriasis Area and Severity Index (PASI) 100 and At Least 10% Weight ReductionPhase 3CompletedDrug: Ixekizumab, TirzepatidePsoriasis, Obesity2812024-09-302026-01-08actual2026-06-17
GAIAGaia AG$36MEffectiveness of a Digital Health Application for PsoriasisNCT06027034Health-Related Quality of LifeNot applicableCompletedBehavioral: Online program for psoriasis (GAIA-PSO-01)Psoriasis3482023-09-042024-12-31actual2026-06-16
BMYBristol-Myers Squibb$134.9BA Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community SettingNCT05701995results2025-09-10Percentage of Participants Achieving Dermatology Life Quality Index (DLQI) Score of 0 or 1 at Week 16Phase 4CompletedDrug: Deucravacitinib · Other: PlaceboPsoriasis1802023-01-312024-08-23actual2026-06-03
LLYEli Lilly and Company$1.15TA Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)NCT06857942Percentage of Participants Achieving Dermatology Life Quality Index (DLQI) (0,1)Phase 4RecruitingDrug: TirzepatidePsoriasis, Overweight or Obesity2002025-03-19May 2028≤ 650 d2026-06-03
ARQTArcutis Biotherapeutics, Inc.$3.3BMaximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body PsoriasisNCT07340216Concentration of Roflumilast and Roflumilast N-Oxide from plasmaPhase 1CompletedDrug: ARQ-154 Foam 0.3%Psoriasis222025-12-152026-04-30actual2026-05-22
BMYBristol-Myers Squibb$134.9BA Real-world Study to Evaluate the Effectiveness of Deucravacitinib in Adults With Plaque Psoriasis in France (RePhlect)NCT06701513observationalPhysician's Global Assessment (PGA) 0/1 responseRecruitingDrug: DeucravacitinibPsoriasis3502025-01-292028-04-30in 619 d2026-05-18
ABBVAbbVie$457.5BStudy to Assess the Safety and Change in Disease Symptoms of Risankizumab (Skyrizi) in Adult Participants With Moderate to Severe Plaque Psoriasis and Psoriatic ArthritisNCT04433442observationalNumber of Participants who Reported Adverse EventsCompletedPsoriasis, Psoriatic Arthritis2,3242020-08-042025-06-13actual2026-04-27
OGNOrganon and Co$3.6BTapinarof for the Treatment of Plaque Psoriasis in Pediatric SubjectsNCT05172726Adverse Events (AEs) and Serious Adverse Events (SAEs)Phase 3Active, not recruitingDrug: tapinarof cream, 1%Plaque Psoriasis582021-12-02Oct 2026≤ 72 d2026-04-17
BMYBristol-Myers Squibb$134.9BA Study to Evaluate Effectiveness and Safety of Deucravacitinib in Participants With Non-Pustular Palmoplantar and Genital PsoriasisNCT06042920results2026-04-17Percentage of Participants Achieving Palmoplantar Psoriasis Area and Severity Index (Pp-PASI)-75 ResponsePhase 4Terminatedsponsor's stated reason: Business objectives have changedDrug: Deucravacitinib, PlaceboPalmoplantar Psoriasis, Genital Psoriasis1302023-10-092025-04-25actual2026-04-17
ABBVAbbVie$457.5BA Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body)NCT06333860Period A: Percentage of Participants Achieving 90% Improvement in Psoriasis Area Severity Index (PASI) Score (PASI 90)Phase 4CompletedDrug: Risankizumab, DeucravacitinibModerate Plaque Psoriasis3932024-05-102026-03-19actual2026-04-15
BMYBristol-Myers Squibb$134.9BA Observational Study to Evaluate Deucravacitinib in Patients With Moderate Plaque Psoriasis in ChinaNCT06512337observationalNumber of participants achieving Static Physician's Global Assessment (sPGA) 0/1 scoreActive, not recruitingDrug: DeucravacitinibPlaque Psoriasis1532025-01-202027-03-11in 203 d2026-04-15
ALMSAlumis Inc$2.1BLong-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque PsoriasisNCT06846541To assess the long-term safety and tolerability of ESK-001 throughout the duration of the studyPhase 3Active, not recruitingDrug: Open-Label Envudeucitinib, Blinded Envudeucitinib, PlaceboPlaque Psoriasis, Psoriasis (PsO), Psoriasis, Moderate Psoriasis, Severe Psoriasis1,6802025-01-08Nov 2028≤ 833 d2026-04-13
068270.KSCelltrion$30.7BA Study to Evaluate the Safety of Remsima® SC in the Treatment of RA, AS, PsA and PsNCT05866614observationalevaluation of adverse events of special interest (AESI)Active, not recruitingDrug: Remsima IV, Remsima SCRheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis8812023-01-13Mar 2027≤ 223 d2026-03-31
VNDAVanda Pharmaceuticals$329MStudy to Evaluate the Long-Term Safety and Efficacy of Imsidolimab (ANB019) in the Treatment of Subjects With GPPNCT05366855results2026-03-27Incidence of Adverse EventsPhase 3Terminatedsponsor's stated reason: AnaptysBio has concluded the GEMINI-2 trial, with all trial participants having been treated with imsidolimab for approximately six months and the furthest subject having been treated through 104 weeks.Drug: Double-blind 200 mg imsidolimab, Open-label 200 mg imsidolimab, Imsidolimab 750 mg IV/200 mg SC · Other: Placebo, Standard of Care (SOC)Generalized Pustular Psoriasis422022-04-212024-07-12actual2026-03-27
ABBVAbbVie$457.5BAn Observational Study to Validate the Cumulative Life Course Impairment (CLCI) Instrument (DermCLCI-p) in Adult Participants With Moderate to Severe Chronic Plaque Psoriasis (PsO)NCT05959070observationalValidity of the Cumulative Life Course Impairment Instrument (DermCLCI-p)CompletedPsoriasis1542023-11-092025-03-21actual2026-03-25
VNDAVanda Pharmaceuticals$329MStudy to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With GPPNCT05352893results2026-03-17Percentage of Patients Achieving a GPPPGA Score of 0 (Clear) or 1 (Almost Clear)Phase 3CompletedDrug: 750 mg Imsidolimab, 300 mg Imsidolimab · Other: PlaceboGeneralized Pustular Psoriasis452022-04-142023-08-17actual2026-03-17
ALM.MCAlmirall, S.A.$2.2BObservational Study of Tildrakizumab in Patients With Moderate to Severe Plaque Psoriasis in Routine Clinical PracticeNCT04203693results2026-03-02observationalCohort 1: Absolute Psoriasis Area and Severity Index (PASI) Score at Week 48CompletedDrug: TildrakizumabPlaque Psoriasis3312019-10-302024-05-02actual2026-03-02
ABBVAbbVie$457.5BStudy to Assess the Safety and Efficacy of Subcutaneously Injected Risankizumab in Adult Participants With Genital or Scalp PsoriasisNCT05969223results2026-02-24Study-G: Percentage of Participants With Achievement of Static Physician Global Assessment of Genitalia (sPGA-G) of 0 or 1 at Week 16Phase 4CompletedDrug: Risankizumab, Placebo for RisankizumabGenital Psoriasis, Scalp Psoriasis2142023-08-102025-01-22actual2026-02-24
068270.KSCelltrion$30.7BA Study to Compare Efficacy and Safety of CT-P55 and Cosentyx in Patients With Moderate to Severe PsoriasisNCT06630559Percent change from baseline in Psoriasis Area and Severity Index (PASI) scorePhase 3Active, not recruitingBiological: CT-P55, EU-approved CosentyxPlaque Psoriasis1532025-05-262026-02-18actual2026-02-23
ABBVAbbVie$457.5BStudy to Evaluate the Effectiveness of Risankizumab in Participants With a Recent Diagnosis of Moderate Plaque Psoriasis in a Real-life Setting in GreeceNCT06247319observationalProportion of participants achieving Psoriasis Area and Severity Index (PASI) score less than or equal to 2Active, not recruitingModerate Plaque Psoriasis, Moderate Psoriasis, Psoriasis2502024-04-29Oct 2027≤ 437 d2026-02-04
AMGNAmgen$229.9BA Study to Investigate Efficacy and Safety of Apremilast 30 mg Twice Daily (BID) in Chinese Participants With Moderate to Severe Plaque-type Psoriasis (PsO)NCT06122649Number of Participants Achieving at least a 75% Reduction (Improvement) From Baseline in Psoriasis Area and Severity Index (PASI) at Week 16Phase 3CompletedDrug: apremilast, PlaceboPlaque Psoriasis2032023-11-272025-02-28actual2026-01-05
AMGNAmgen$229.9BA Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque PsoriasisNCT04175613Adverse Events (AEs)Phase 3CompletedDrug: ApremilastPsoriasis1602019-12-202025-10-30actual2025-12-22
BMYBristol-Myers Squibb$134.9BA Study to Evaluate Deucravacitinib in Participants With Moderate-to-Severe Plaque Psoriasis in GermanyNCT06104644observationalProportion of patients achieving an absolute Psoriasis Area Severity Index (aPASI) score ≤ 3 at Week 24 or nearest visitActive, not recruitingDrug: DeucravacitinibPlaque Psoriasis5502023-04-132025-08-18actual2025-12-04
XNCRXencor, Inc.$1.9BMultiple Ascending-Dose Study of XmAb®27564 in Patients With Psoriasis or Atopic DermatitisNCT06005792To evaluate the safety and tolerability of multiple ascending dose subcutaneous (SC ) administration of XmAb27564Phase 1Terminatedsponsor's stated reason: Business DecisionBiological: XmAb27564, PlaceboPsoriasis, Atopic Dermatitis232022-10-102024-03-22actual2025-12-02
BMYBristol-Myers Squibb$134.9BDeucravacitinib for Patients With Moderate/Severe Psoriasis: A Real-Life Experience in ItalyNCT07256015observationalThe percentage of participants still receiving deucravacitinib treatmentRecruitingDrug: DeucravacitinibPsoriasis2002025-08-052027-07-05in 319 d2025-12-01
BMYBristol-Myers Squibb$134.9BA Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe PsoriasisNCT05730725results2025-11-25Percentage of Participants Achiving PASI-75 at Week 12Phase 2CompletedDrug: BMS-986322 · Other: PlaceboPsoriasis1092023-04-032024-08-06actual2025-11-25
ABBVAbbVie$457.5BObservational Study of Patients With Moderate to Severe Chronic Plaque PsoriasisNCT03982394observationalPercentage of participants who achieved Psoriasis Area and Severity Index (PASI) 90CompletedChronic Plaque Psoriasis2,7592019-07-012025-09-02actual2025-11-17
AMGNAmgen$229.9BA Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque PsoriasisNCT06088199Number of Participants With Treatment-emergent Adverse EventsPhase 3Active, not recruitingDrug: ApremilastPlaque Psoriasis512023-10-242026-08-062025-11-17
SNYSanofiA Study to Evaluate Efficacy and Safety of SAR441566 in Adults With Plaque PsoriasisNCT06073119results2025-11-10Percentage of Participants With a 75% or Greater Psoriasis Area and Severity Index (PASI) Score Reduction From Baseline (PASI75) at Week 12Phase 2CompletedDrug: SAR441566, PlaceboPsoriasis2212023-10-262024-11-13actual2025-11-10
BMYBristol-Myers Squibb$134.9BEfficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp PsoriasisNCT05478499results2025-03-13Percentage of Participants With a Scalp-specific Physician Global Assessment Score of 0 or 1 (Ss-PGA 0/1) at Week 16Phase 4CompletedDrug: Deucravacitinib · Other: PlaceboPsoriasis1542022-10-062024-01-11actual2025-10-28
BMYBristol-Myers Squibb$134.9BLong-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With PsoriasisNCT04036435Incidence of Adverse Events (AEs)Phase 3Active, not recruitingDrug: BMS-986165, PlaceboPsoriasis1,4662019-08-122026-07-252025-10-20
LLYEli Lilly and Company$1.15TA Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque PsoriasisNCT06176768results2025-10-15Percentage of Participants Achieving ≥75% Reduction From Baseline in Psoriasis Area and Severity Index (PASI-75)Phase 2CompletedDrug: LY3972406, PlaceboPlaque Psoriasis332023-12-062025-04-01actual2025-10-15
SNYSanofiA Study to Investigate Safety, Tolerability and Clinical Response With SAR441566 Compared With Placebo in Participants With Mild to Moderate PsoriasisNCT05453942Number of participants with treatment-emergent adverse events (TEAE) including SAE and AESIPhase 1CompletedDrug: SAR441566, PlaceboPsoriasis382022-07-122023-02-09actual2025-09-25
ALM.MCAlmirall, S.A.$2.2BA Study to Assess Treatment Satisfaction, Patient-reported Outcomes, Effectiveness, and Safety of a Fixed-dose Combination of Calcipotriene/Betamethasone Dipropionate PAD Cream in the Treatment of Mild-to-moderate Plaque Psoriasis of the Scalp in AdultsNCT05811234results2025-09-24observationalAbsolute Treatment Satisfaction Questionnaire for Medication Version 9 (TSQM-9) Domain Total Score at Week 12CompletedDrug: CAL/BDP PAD CreamPlaque Psoriasis2912023-06-132024-10-01actual2025-09-24
ABBVAbbVie$457.5BStudy to Assess the Change in Disease State When Subcutaneous Risankizumab Injection is Given to Adult Participants With Psoriasis in TaiwanNCT04818385observationalThe Percentage of Participants who Achieved Psoriasis Area and Severity Index (PASI) 90CompletedPsoriasis2402021-05-312025-08-01actual2025-09-17
VNDAVanda Pharmaceuticals$329MA Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Generalized Pustular PsoriasisNCT03619902results2022-03-29Percentage of Participants Achieving Clinical Response on the Clinical Global Impression (CGI) ScalePhase 2CompletedBiological: ImsidolimabGeneralized Pustular Psoriasis82019-01-302021-01-20actual2025-09-16
AMGNAmgen$229.9BPost-Marketing Surveillance Study of OTEZLANCT03284879observationalAdverse Events (AEs)CompletedPsoriasis1,0862017-09-052021-10-31actual2025-09-08
LLYEli Lilly and Company$1.15TA Study of Ixekizumab (LY2439821) in Participants Aged ≥18 Years With Moderate-to-Severe Plaque or Active Psoriatic Arthritis in IndiaNCT05855967results2025-08-22Number of Participants Reporting Serious Adverse Events (SAEs), and Treatment Emergent Adverse Events (TEAEs) and AEs of Special Interests (AESIs) From Week 0 to Week 24Phase 4CompletedDrug: IxekizumabPlaque Psoriasis, Psoriatic Arthritis2502023-06-272024-08-08actual2025-08-22
ABBVAbbVie$457.5BStudy to Assess Change in Disease Symptoms in Adult Participants With Moderate to Severe Psoriasis Treated With Subcutaneous Risankizumab Injection According to Standard of CareNCT04780516observationalPercentage of Participants Who Achieved Dermatology Life Quality Index (DLQI) 0 or 1Active, not recruitingPsoriasis1412021-04-262024-01-02actual2025-08-13
ABBVAbbVie$457.5BStudy to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977NCT04862286Number of Participants With Adverse EventsPhase 3Active, not recruitingDrug: RisankizumabPsoriasis1322021-07-24Apr 2028≤ 619 d2025-08-12
OGNOrganon and Co$3.6BLong Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003)NCT04053387results2022-08-08Number of Subjects With Adverse Events and Serious Adverse EventsPhase 3CompletedDrug: tapinarof cream, 1%Plaque Psoriasis7632019-08-132021-04-06actual2025-08-06
ARQTArcutis Biotherapeutics, Inc.$3.3BTopical Roflumilast to Treat Scalp and Body Psoriasis (ARRECTOR)NCT05028582results2025-07-17Achievement of Scalp Investigator Global Assessment (S-IGA) "Success" at Week 8Phase 3CompletedDrug: Roflumilast Foam 0.3%, Vehicle FoamScalp Psoriasis4322021-08-242022-06-03actual2025-07-17
AMGNAmgen$229.9BA Study of the Impact of Apremilast (CC-10004) on Quality of Life, Efficacy, and Safety in Adults With Manifestations of Plaque Psoriasis and Impaired Quality of LifeNCT03774875results2022-01-13Percentage of Participants Who Achieved a ≥ 4-point Reduction From Baseline in Dermatology Life Quality Index (DLQI) at Week 16Phase 4CompletedDrug: Apremilast, PlaceboPsoriasis2772019-03-282021-02-01actual2025-07-10
BMYBristol-Myers Squibb$134.9BA Study to Assess Deucravacitinib Post-marketing Surveillance in Participants With Psoriasis in JapanNCT05633264observationalIncidence of Adverse Events (AEs)CompletedPsoriasis3692022-12-052025-05-28actual2025-07-03
ALM.MCAlmirall, S.A.$2.2BA Study to Assess Patient-Reported Wellbeing Using Tildrakizumab in a Live SettingNCT06488170observationalChange From Baseline in 5-item World Health Organization Wellbeing Index (WHO-5) ScoreActive, not recruitingDrug: TildrakizumabPlaque Psoriasis422024-04-04Jan 20262025-06-24
PFEPfizer$155.3BInfliximab Biosimilar for Intravenous Drip Infusion 100 mg "Pfizer" Drug Use Investigation (Psoriasis)NCT03885089results2025-06-19observationalNumber of Participants With Adverse Drug ReactionsCompletedDrug: Infliximab [infliximab biosimilar 3]Psoriasis Vulgaris, Psoriasis Arthropathica, Pustular Psoriasis, Erythrodermic Psoriasis102019-10-212024-03-08actual2025-06-19
OGNOrganon and Co$3.6BMaximal Use Study of Tapinarof Cream, 1% in Adults With Extensive Plaque PsoriasisNCT04042103results2022-05-06Number of Participants That Experienced Adverse Events (AEs), Severe Adverse Events, and Serious Adverse Events (SAEs)Phase 2CompletedDrug: Tapinarof cream, 1%Plaque Psoriasis212019-07-232020-01-09actual2025-06-19
ALMSAlumis Inc$2.1BA Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque PsoriasisNCT05600036results2024-07-23To Compare the Psoriasis Area and Severity Index (PASI-75) Between Doses of ESK-001 and PlaceboPhase 2CompletedDrug: ESK-001, PlaceboPlaque Psoriasis2282022-09-272023-06-29actual2025-06-18
OGNOrganon and Co$3.6BTapinarof for the Treatment of Plaque Psoriasis in Adults (3001)NCT03956355results2022-10-13Percent of Subjects Who Achieve a Physician Global Assessment (PGA) Score of Clear (0) or Almost Clear (1) With a Minimum 2-grade Improvement From Baseline at Week 12. Analyses Were Done Using Multiple ImputationPhase 3CompletedDrug: Tapinarof, Vehicle CreamPlaque Psoriasis5102019-05-212020-05-26actual2025-06-12
OGNOrganon and Co$3.6BTapinarof for the Treatment of Plaque Psoriasis in Adults (3002)NCT03983980results2022-10-13Percent of Subjects Who Achieve a Physician Global Assessment (PGA) Score of Clear (0) or Almost Clear (1) With a Minimum 2-grade Improvement From Baseline at Week 12. Analyses Were Done Using Multiple ImputationPhase 3CompletedDrug: Tapinarof, Vehicle CreamPlaque Psoriasis5152019-06-062020-05-13actual2025-06-12
OGNOrganon and Co$3.6BA Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque PsoriasisNCT05680740results2024-07-08Percentage of Participants Who Achieve an Intertriginous PGA (iPGA) Score of Clear (0) or Almost Clear (1) With a ≥ 2-grade ImprovementPhase 4CompletedDrug: VTAMA® (tapinarof) Cream 1%Psoriasis342022-12-272023-05-18actual2025-06-12
OGNOrganon and Co$3.6BA Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck RegionNCT05789576results2024-08-09Percentage of Participants Who Achieve a Target Lesion Physician Global Assessment (PGA) Score in the Head and Neck Region of Clear (0) or Almost Clear (1) With a ≥ 2-grade ImprovementPhase 4CompletedDrug: VTAMA (tapinarof) cream, 1%Psoriasis312023-03-132023-06-30actual2025-06-12
BMYBristol-Myers Squibb$134.9BA Study to Assess Deucravacitinib Safety in PregnancyNCT07017699observationalNumber of major congenital malformations among infantsRecruitingDrug: Deucravacitinib, Other systemic treatments for PsOPsoriasis (PsO)9002025-03-212028-04-01in 590 d2025-06-12
PFEPfizer$155.3BA Study to Learn About the Study Medicine Called Infliximab (Genetical Recombination)[Infliximab Biosimilar 3] in People With Rheumatoid Arthritis, Ulcerative Colitis, Crohn's Disease, or PsoriasisNCT05796245results2025-06-04observationalIncidence Rate of Serious InfectionsCompletedArthritis, Rheumatoid, Colitis, Ulcerative, Crohn Disease, Psoriasis2,2072023-12-012024-03-14actual2025-06-04
ABBVAbbVie$457.5BA Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disease SymptomsNCT04435600results2025-05-20Percentage of Participants Achieving Psoriasis Area Severity Index (PASI) 75 (Defined as at Least 75% Improvement in PASI)Phase 3CompletedDrug: Risankizumab, UstekinumabPsoriasis1392020-07-142024-02-12actual2025-05-20
ALM.MCAlmirall, S.A.$2.2BObservational Real-world Evidence (RWE) Study to Assess Patient-reported Wellbeing Using Tildrakizumab in Live Setting - POSITIVE StudyNCT04823247observationalChange From Baseline in 5-item World Health Organization Wellbeing Index (WHO-5) ScoreCompletedDrug: TildrakizumabPlaque Psoriasis7822021-11-222025-01-09actual2025-05-11
BMYBristol-Myers Squibb$134.9BA Study Comparing the Risk of Serious Infections and Malignancies With Deucravacitinib or Biologics in Japanese Patients With PsoriasisNCT06952465observationalParticipant baseline demographicsActive, not recruitingDrug: Deucravacitinib · Biological: Any biologic treatment for psoriasisPsoriasis2,0002025-01-242031-11-30in 1,928 d2025-05-01
CANFCan-Fite BioPharmaA Phase 3 Study in Moderate-to-Severe Plaque Psoriasis With Piclidenoson to Study Safety and EfficacyNCT06643260Proportion of subjects who achieve a Psoriasis Area and Severity Index (PASI) score response of ≥75% (PASI 75)Phase 3Not yet recruitingDrug: piclidenoson, PlaceboPlaque Psoriasis705Jun 2025Dec 2027≤ 498 d2025-04-29
LLYDICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company$1.15TA Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque PsoriasisNCT05896527results2025-04-04Percentage of Participants Achieving ≥75% Reduction From Baseline in Psoriasis Area and Severity Index (PASI-75) at Week 12Phase 2CompletedDrug: DC-806 · Other: PlaceboPlaque Psoriasis2292023-05-022024-03-25actual2025-04-04
ALDXAldeyra Therapeutics, Inc.$94MA Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of Subjects With Plaque PsoriasisNCT04908514results2025-03-11Change From Baseline in the Psoriasis Area and Severity Index (PASI)Phase 2CompletedDrug: ADX-629Plaque Psoriasis102021-05-072022-01-21actual2025-03-11
LLYDICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company$1.15TA Study to Assess S011806 (DC-806 or LY4100504) in Healthy Adult Participants and Participants With Chronic Plaque PsoriasisNCT06808815Part 1: Number of Participants with One or More Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug.Phase 1CompletedDrug: DC-806 · Other: PlaceboPlaque Psoriasis1042021-09-222022-08-23actual2025-02-05
ALM.MCAlmirall, S.A.$2.2BA Study of Tildrakizumab in the Treatment of Genital Psoriasis (CZATCH-Genital-PsO)NCT06029257observationalPercentage of Participants Achieving a Static Physician's Global Assessment of Genitalia (sPGA-G) Score of "Clear" (0) or "Almost Clear" (1)RecruitingDrug: TildrakizumabGenital Psoriasis1102023-11-14Mar 20262025-01-29
ALM.MCAlmirall, S.A.$2.2BA Study to Assess the Effects of Switching From a Biologic Treatment to Tildrakizumab Using Patient-reported Outcomes in Adult Participants With Moderate to Severe Plaque PsoriasisNCT06030076observationalTreatment Satisfaction Questionnaire for Medication-11 (TSQM-11) ScoreRecruitingDrug: TildrakizumabPlaque Psoriasis502023-09-06Oct 20252025-01-29
ARQTArcutis Biotherapeutics, Inc.$3.3BOpen-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque PsoriasisNCT04286607Occurrence of treatment emergent AEs (TEAEs)Phase 3CompletedDrug: Topical roflumilastChronic Plaque Psoriasis3332020-02-122024-01-22actual2025-01-07
AMGNAmgen$229.9BEfficacy and Safety Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque PsoriasisNCT03701763results2023-12-07Percentage of Participants With a Static Physician Global Assessment (sPGA) Response at Week 16Phase 3CompletedDrug: Apremilast (CC-10004) · Other: PlaceboPsoriasis2452018-12-192022-04-25actual2024-12-16
AMGNAmgen$229.9BA Study to Investigate ABP 654 for the Treatment of Participants With Moderate to Severe Plaque PsoriasisNCT04607980results2023-12-15PASI Percent Change From Baseline to Week 12Phase 3CompletedDrug: ABP 654, UstekinumabPlaque Psoriasis5632020-11-112022-01-13actual2024-12-12
ABBVAbbVie$457.5BA Study to Assess the Safety and Efficacy of Risankizumab for Maintenance in Moderate to Severe Plaque Type Psoriasis ( LIMMITLESS )NCT03047395results2024-12-11Number of Participants With Serious Adverse Events and Non-Serious Adverse EventsPhase 3CompletedBiological: risankizumabPsoriasis2,1702017-02-272023-11-29actual2024-12-11
BMYBristol-Myers Squibb$134.9BA Study on the Safety of Deucravacitinib Exposure in Pregnant Women and Their OffspringNCT06710470observationalNumber of infants born with Major Congenital Malformations (MCMs)Active, not recruitingDrug: Deucravacitinib, Systemic psoriasis medications · Other: No systemic medicationsPsoriasis8332024-08-022027-01-31in 164 d2024-11-29
ABBVAbbVie$457.5BEffect of Long-term Psoriasis on Patients' Life - CORONATENCT05555953observationalCORONATE Questionnaire ScoreCompletedPsoriasis5432023-01-262024-10-17actual2024-10-26
4503.TAstellas Pharma Inc$26.0BA Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe PsoriasisNCT01096862Change from baseline to the end of treatment in Psoriasis Area Severity Index (PASI) scorePhase 2CompletedDrug: peficitinib, PlaceboPsoriasis1242010-03-232011-07-27actual2024-10-21
PFEPfizer$155.3BA Study to Learn About The Study Medicine (PF-07038124) In Patients With Mild To Moderate Atopic Dermatitis Or Mild To Severe Plaque Psoriasis.NCT05375955results2024-10-02Percentage of Participants With Investigator's Global Assessment (IGA) Score of Clear (0) or Almost Clear (1) and a Reduction From Baseline of More Than or Equal to (>=) 2 Points at Week 12: Participants With Atopic Dermatitis (AD) OnlyPhase 2CompletedDrug: PF-07038124 ointment 0.01%, Vehicle ointment, PF-07038124 ointment 0.03%, PF-07038124 ointment 0.06%Atopic Dermatitis, Plaque Psoriasis2632022-09-262023-07-31actual2024-10-02
PFEWyeth is now a wholly owned subsidiary of Pfizer$155.3BStudy Evaluating The Safety And Tolerability Of ILV-094 In Subjects With PsoriasisNCT00563524results2024-08-23Number of Participants With Treatment-Emergent Adverse Events (AEs) And Serious Adverse Events (SAEs)Phase 1CompletedDrug: ILV-094Psoriasis762007-12-202010-06-14actual2024-08-23
068270.KSCelltrion$30.7BTo Compare Pharmacokinetics, Efficacy, and Safety of CT-P17 With Humira in Patients With Moderate to Severe Chronic Plaque PsoriasisNCT05495568To demonstrate the pharmacokinetics (PK) similarity between patients receiving Humira continuously and those who alternate between Humira and CT-P17 in terms of Area under the concentration-time curve over the dosing interval (AUCtau, 25-27)Phase 3CompletedBiological: CT-P17, EU-approved HumiraModerate to Severe Chronic Plaque Psoriasis3672022-11-072023-08-14actual2024-08-21
OGNOrganon and Co$3.6BElocon vs Fluticasone in Localized Psoriasis (P03197)NCT00763529Reduction in mean symptom scores for erythema, induration, pruritus, and scaling on Day 4.Phase 4CompletedDrug: Mometasone, FluticasonePsoriasis2452003-01-012005-01-01actual2024-08-15
LLYEli Lilly and Company$1.15TA Safety Study of Mirikizumab (LY3074828)NCT01947933results2024-07-25Number of Participants With One or More Adverse Event(s) (AEs) Considered by the Investigator to Be Related to Study Drug AdministrationPhase 1CompletedBiological: Mirikizumab- IV, Mirikizumab - SC, Placebo - IVPsoriasis45Oct 2013Feb 2015actual2024-07-25
BMYBristol-Myers Squibb$134.9BA Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque PsoriasisNCT05744466observationalChange in body surface area (BSA)RecruitingDrug: Deucravacitinib, ApremilastPsoriasis1,5002022-09-302027-12-10in 477 d2024-07-23
PFEPfizer$155.3BStudy Evaluating Single Dose Of ILV-095 In Psoriasis SubjectsNCT01010542results2024-07-03Percentage of Participants With 50 Percent Improvement From Baseline in Total Psoriasis Area Severity Index (PASI) Score at Week 2Phase 1Terminatedsponsor's stated reason: See termination reason in detailed description.Drug: ILV-095 300 mg in a 4 to 1 ratio, ILV-095 300 mg in a 4 to 1 ratioPlaque Psoriasis392009-12-012011-05-20actual2024-07-03
ABBVAbbVie$457.5BStudy of Subcutaneous (Injected Under the Skin) Risankizumab to Assess Change in Disease Symptoms in Adult Participants With Moderate to Severe Plaque Psoriasis With Palmoplantar InvolvementNCT04713592results2024-06-14Percentage of Participants Achieving Palmoplantar Investigator's Global Assessment (ppIGA) of "Clear" or "Almost Clear" (0 or 1) With at Least a 2-point Reduction From Baseline at Week 16Phase 3CompletedDrug: Placebo for Risankizumab, RisankizumabPsoriasis1742021-02-262023-04-20actual2024-06-14
AMGNAmgen$229.9BStudy to Evaluate the Benefits for the Patient Associated With the Treatment of Plaque Psoriasis With Apremilast After Other Systemic Treatment in Conditions of Clinical Practice in SpainNCT03539419observationalPercentage of subjects achieving PBI ≥ 1CompletedPsoriasis1532018-06-122019-11-02actual2024-06-05
AMGNAmgen$229.9BApremilast as a Direct Treatment for Mild-to-moderate Plaque Psoriasis Versus Placebo: an Analysis of Clinical Safety and EfficacyNCT03721172results2021-05-17Percentage of Participants With a Static Physician Global Assessment (sPGA) Response at Week 16 During the Placebo-Controlled PhasePhase 3CompletedDrug: Apremilast · Other: PlaceboPsoriasis5952019-03-112020-03-06actual2024-05-29
AMGNAmgen$229.9BAn Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate to Severe Genital PsoriasisNCT03777436results2022-12-15Percentage of Participants With a Modified sPGA-G Response at Week 16Phase 3CompletedDrug: Apremilast · Other: PlaceboPsoriasis2892019-02-112021-09-23actual2024-05-14
AMGNAmgen$229.9BObservational Study of Apremilast in Patients With Psoriasis in The NetherlandsNCT02652494observationalPercentage of patients with Dermatology Life Quality Index (DLQI) ≤ 5 pointsCompletedPsoriasis1542016-02-222019-12-31actual2024-05-13
ABBVAbbVie$457.5BStudy of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic TherapyNCT04908475results2024-04-30Percentage of Participants Achieving Psoriasis Area Severity Index (PASI) 90 (Defined as at Least 90% Improvement in PASI From Baseline) in Intent to Treat Population at Week 16 (ITT_A)Phase 4CompletedDrug: Risankizumab, ApremilastPsoriasis3522021-06-092023-04-20actual2024-04-30
BMYBristol-Myers Squibb$134.9BA Study of the Comparative Effectiveness of Deucravacitinib in Adults With Plaque Psoriasis in Japan (RePhlect)NCT06382987observationalChange in percent Body Surface Area (BSA) involved affected by plaque psoriasis from baseline to follow up in participants treated with deucravacitinib.RecruitingDrug: Deucravacitinib, ApremilastPlaque Psoriasis6002024-01-222029-12-31in 1,229 d2024-04-25
ABBVAbbVie$457.5BChronic Plaque Psoriasis (Ps) RegistryNCT00799877observationalIncidence of Serious Adverse EventsCompletedChronic Plaque Psoriasis6,0652008-09-262023-02-13actual2024-03-15

Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.

How Psoriasis is matched — 17 exact registry spellings

A study is on this page when its ClinicalTrials.gov record names one of these conditions exactly (letter case aside). Nothing is matched by substring or stem, so a longer condition that merely contains one of these words is a different page. The list was curated by hand and last measured 2026-08-19; a spelling filed by only one study was not curated, so the counts here are a floor rather than the registry's own total for the disease.

  • Psoriasis
  • Plaque Psoriasis
  • Chronic Plaque Psoriasis
  • Psoriasis Vulgaris
  • Generalized Pustular Psoriasis
  • Genital Psoriasis
  • Moderate to Severe Plaque Psoriasis
  • Nail Psoriasis
  • Plaque Psoriasis Vulgaris
  • Erythrodermic Psoriasis
  • Moderate Plaque Psoriasis
  • Moderate Psoriasis
  • Moderate to Severe Chronic Plaque Psoriasis
  • Plaque-type Psoriasis
  • Psoriasis (PsO)
  • Pustular; Psoriasis, Palmaris Et Plantaris
  • Scalp Psoriasis

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