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Ovarian Cancer trial readouts

registry pull 2026-08-19

Primary-completion dates that listed drug and biotech companies filed with ClinicalTrials.gov for studies in Ovarian Cancer. They are the sponsor's own estimated windows, revised as a study runs — not announcement dates. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Upcoming readout windows

next 180 days · by month

15 studies across 14 companies, in the next 180 days.

August 2026 3

TickerNameStudyPhaseStatusPrimary completionReadout inUpdated
CORTCorcept TherapeuticsRelacorilant in Combination With Different Treatment Regimens in Patients With Gynecological CancersNCT06906341Progression-Free Survival (PFS)Phase 2RecruitingAug 2026≤ 11 d2026-07-16
NRIXNurix Therapeutics, Inc.A Study of NX-1607 in Adults With Advanced MalignanciesNCT05107674Incidence of treatment-emergent adverse events (TEAEs), including Grade ≥ 3 TEAEs, treatment-emergent serious adverse events (SAEs), TEAEs leading to study drug discontinuation, and deaths due to TEAEsPhase 1Recruiting2026-08-31in 11 d2025-09-09
RADXRadiopharm Theranostics, LtdSafety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid TumorsNCT05799274Radiation dosimetry of RAD301Phase 1RecruitingAug 2026≤ 11 d2026-07-17

October 2026 2

TickerNameStudyPhaseStatusPrimary completionReadout inUpdated
TEMTempus AITempus Priority Study: A Pan-tumor Observational StudyNCT05179824observationalCreate robust data set of health informationActive, not recruiting2026-10-19in 60 d2025-05-06
IDYAIDEAYA BiosciencesA Study of PARG Inhibitor IDE161 in Participants With Advanced Solid TumorsNCT05787587Part 1 (Dose Escalation): To characterize the safety and tolerability of IDE161 monotherapy or in combination with pembrolizumab to determine the MTD and/or RDEPhase 1Active, not recruitingOct 2026≤ 72 d2026-07-13

November 2026 1

TickerNameStudyPhaseStatusPrimary completionReadout inUpdated
ABBVAbbVieA Study to Evaluate Folate Receptor Alpha (FRα) Expression in Adult Participants With Ovarian, Fallopian Tube, and Primary Peritoneal Cancer in ItalyNCT07407062observationalFRα - Positive StatusRecruitingNov 2026≤ 102 d2026-07-27

December 2026 9

TickerNameStudyPhaseStatusPrimary completionReadout inUpdated
TCRXTScan Therapeutics, Inc.A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid TumorsNCT05973487Evaluate the safety of monotherapy and T- Plex combination TCR-TsPhase 1Active, not recruiting2026-12-30in 132 d2025-11-17
BCAXBicara TherapeuticsStudy of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid TumorsNCT04429542Safety of BCA101 alone and BCA101 in combination with pembrolizumab: Incidence and severity of AEs and SAEsPhase 1Recruiting2026-12-31in 133 d2025-08-15
CNTXContext Therapeutics Inc.CT-95 in Advanced Cancers Associated With Mesothelin ExpressionNCT06756035Determine the MTD or RD of CT-95 [Safety and Tolerability]Phase 1RecruitingDec 2026≤ 133 d2026-06-12
GNLXGenelux CorporationEfficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)NCT05281471Progression-free survival (PFS) by RECIST 1.1 in the Intention-to-Treat (ITT) population (all randomized participants regardless of whether they received any dose of treatment)Phase 3RecruitingDec 2026≤ 133 d2026-07-10
JAZZJazz PharmaceuticalsA Phase 2 Study of Zanidatamab in Patients With HER2-expressing TumorsNCT06695845Confirmed Objective Response Rate (cORR) per RECIST Version 1.1, as assessed by ICRPhase 2Recruiting2026-12-31in 133 d2026-07-10
MNPRMonopar TherapeuticsDose-Escalation of MNPR-101-PCTA-177Lu in Solid TumorsNCT06617169Identify the dose-limiting toxicities (DLTs) of fractionated MNPR-101-PCTA-177Lu dosing and their frequencyPhase 1RecruitingDec 2026≤ 133 d2025-05-21
NXTCNextCure, Inc.A Phase 1 Study of LNCB74 in Advanced Solid TumorsNCT06774963Evaluate the safety and tolerability of LNCB74Phase 1RecruitingDec 2026≤ 133 d2025-12-16
PFEPfizerPF-07104091 as a Single Agent and in Combination TherapyNCT04553133Dose Escalation: Number of participants with Dose-limiting toxicities (DLT) during first cyclePhase 2Active, not recruiting2026-12-31in 133 d2026-05-06
PFEPfizerContinued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are ClosingNCT05059522Number of participants with adverse events leading to permanent discontinuation of study interventionPhase 3Active, not recruiting2026-12-31in 133 d2026-06-22

Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.

Every registered study in Ovarian Cancer

most recently updated first

306 studies match. Showing the first 100 of 306 studies — page through, or narrow the filters.

TickerNameMarket capStudyPhaseStatusInterventionsConditionsEnrollmentStartPrimary completionReadout inUpdated
AZNAstraZenecaStudy of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid MalignanciesNCT04644068The number of subjects with adverse events/serious adverse eventsPhase 1/2Active, not recruitingDrug: AZD5305, Paclitaxel, Carboplatin, T- Dxd, Dato-DXd, CamizestrantOvarian Cancer, Breast Cancer, Pancreatic Cancer, Prostate Cancer, Additional Indications Below for Module 4 and 5, Non-small Cell Lung Cancer, Colorectal Cancer, Bladder Cancer, Gastric Cancer, Biliary Cancer, Cervical Cancer, Endometrial Cancer, Small Cell Lung Cancer Only in Module 57022020-11-122027-05-28in 281 d2026-08-19
BOLDBoundless Bio, Inc.$65MStudy of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene AmplificationsNCT05827614Frequency and severity of treatment emergent adverse events (TEAEs) of BBI-355 as a single agent and in combination with each of the following agents: erlotinib, futibatinib, or BBI-825Phase 1Terminatedsponsor's stated reason: Decision was made to halt the study based on overall clinical experience and market considerations. This decision was not driven by any safety signal.Drug: BBI-355, Erlotinib, Futibatinib, BBI-825Triple Negative Breast Cancer (TNBC), High Grade Serous Ovarian Carcinoma, High Grade Endometrial Carcinoma, Anogenital Cancer, Head and Neck (HNSCC), Cutaneous Squamous Cell Carcinoma (CSCC), Cervical Squamous Cell Carcinoma, ER+ Breast Cancer, Leiomyosarcoma (LMS), Undifferentiated Pleomorphic Sarcoma (UPS), Pancreatic Cancer Metastatic, Small Cell Lung Cancer852023-03-242026-03-17actual2026-08-19
AZNAstraZenecaA Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid TumorsNCT07115043Safety- Part 1A & Part 2A (dose escalation) and Part 2B (dose expansion)Phase 1/2RecruitingDrug: AZD6750, rilvegostomigMelanoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma (Skin), Renal Cell Carcinoma, Merkel Cell Carcinoma, Triple Negative Breast Cancer, Head and Neck Squamous Cell Carcinoma, Gastric Cancer/Gastroesophageal Junction Cancer, High Grade Serous Ovarian Carcinoma1202025-07-292029-10-02in 1,139 d2026-08-19
WHWKWhitehawk Therapeutics, Inc.$271MA Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.NCT07470853Determine Maximum Tolerated Dose (MTD)Phase 1RecruitingDrug: HWK-016, MUCIN-16-targeted ADC, BevacizumabPROC, Platinum Resistant Ovarian Cancer, Endometrial Cancer2652026-03-15Feb 2028≤ 558 d2026-08-18
BMYBristol-Myers Squibb$134.9BA Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid TumorsNCT04895709Incidence of adverse events (AEs)Phase 1/2RecruitingDrug: BMS-986340, BMS-936558-01, Docetaxel, PumitamigCervical Cancer, Gastric/Gastroesophageal Junction Adenocarcinoma, Microsatellite Stable Colorectal Cancer, Non-Small-Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Urothelial Carcinoma, Pancreatic Adenocarcinoma, Melanoma, Ovarian Neoplasms, Triple Negative Breast Neoplasms1,1092021-05-272031-08-31in 1,837 d2026-08-17
NXTCNextCure, Inc.$30MA Phase I Study of SIM0505 in Participants With Advanced Solid TumorsNCT06792552dose escalation: Dose-limiting toxicity (DLT)Phase 1RecruitingDrug: SIM0505 for injection, SIM0505 for injectionAdvanced Solid Tumors, Platinum Resistant Ovarian Cancer, Fallopian Tube Cancer, Renal Cell Carcinoma (RCC), Papillary Renal Cell Carcinoma (Prcc), Uterine Serous Carcinoma (USC), NSCLC (Non-small Cell Lung Cancer), Primary Peritoneal Cancer7382025-02-26Feb 2028≤ 558 d2026-08-17
VSTMVerastem, Inc.$673MA Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian CancerNCT06072781Progression Free Survival (PFS) per blinded independent central review (BICR)Phase 3RecruitingDrug: avutometinib, Defactinib, Pegylated liposomal doxorubicin, Paclitaxel, Letrozole, AnastrozoleLow Grade Serous Ovarian Cancer2702024-03-182028-10-15in 787 d2026-08-14
ABBVAbbVie$457.5BA Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.NCT06890338Objective Response (OR) by Independent Central Review (ICR)Phase 2RecruitingDrug: Carboplatin, Mirvetuximab Soravtansine, BevacizumabEpithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Neoadjuvant1402025-11-21Feb 2030≤ 1,288 d2026-08-14
AZNAstraZenecaStudy of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)NCT05489211Objective response rate (ORR)Phase 2RecruitingDrug: Datopotamab deruxtecan (Dato-DXd), Capecitabine, 5-Fluorouracil, Volrustomig, Carboplatin, Bevacizumab, Rilvegostomig, Prednisone/ prednisolone, CisplatinEndometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer, Ovarian Cancer, Colorectal Cancer, Urothelial Cancer, Biliary Tract Cancer4542022-09-062027-10-01in 407 d2026-08-13
NXTCNextCure, Inc.$30MA Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid TumorsNCT05572684results2026-08-13Number of Participants With Treatment-emergent Adverse Events as Assessed by CTCAE v5.0Phase 1/2Terminatedsponsor's stated reason: Following completion of Phase 1b, the Sponsor decided not to initiate Part 2 of the trial.Drug: NC410, pembrolizumabAdvanced or Metastatic Solid Tumors, Microsatellite Instability Low, Microsatellite Instability High, Microsatellite Stable, Ovarian Cancer, Gastric Cancer, Colo-rectal Cancer, Esophageal Cancer, Endometrial Cancer, Head Neck Cancer, Cervical Cancer, Lung Cancer972022-10-062025-04-30actual2026-08-13
XNCRXencor, Inc.$1.9BPhase 1, Safety and Tolerability Study of XmAb541 and XmAb808 in Advanced Solid TumorsNCT07593092Incidence of Adverse EventsPhase 1RecruitingBiological: XmAb541, XmAb808Ovarian Cancer902026-06-30Dec 2028≤ 864 d2026-08-13
AZNAstraZenecaA Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid MalignanciesNCT05123482The number of patients with adverse eventsPhase 1/2RecruitingDrug: AZD8205, AZD8205 and AZD2936 (Rilvegostomig), AZD8205 and AZD5305 (saruparib), AZD8205 and AZD5305 (saruparib) and AZD2936 (rilvegostomig), AZD8205 in combination with AZD9574, AZD8205 in combination with AZD9574 plus rilvegostomig (AZD2936)Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer, Endometrial Cancer, Squamous Non-Small Cell Lung Cancer4602021-10-182027-09-29in 405 d2026-08-12
REGNRegeneron Pharmaceuticals$76.1BInvestigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian CancerNCT06787612Objective Response Rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 by investigator assessmentPhase 2RecruitingDrug: Ubamatamab, Bevacizumab, Cemiplimab, Fianlimab, PLD, Sarilumab, REGN10597Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer2972025-05-282028-06-30in 680 d2026-08-12
ZNTLK-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc$264MA Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein ExpressionNCT07546500Progression free survival (PFS) per RECIST v1.1 as assessed by InvestigatorPhase 3RecruitingDrug: Investigator's choice of Chemotherapy, AzenosertibOvarian Cancer4202026-04-172028-05-31in 650 d2026-08-12
MGNXMacroGenics$261MA Study of MGC026 in Participants With Advanced Solid TumorsNCT06242470Number of participants with adverse events (AEs) and serious AEs (SAEs), AEs leading to dose delay, AEs leading to dose reduction, AEs leading to treatment discontinuations, AEs meeting criteria for dose limiting toxicity, and AEs of special interest.Phase 1RecruitingBiological: MGC026 Dose Escalation, MGC026 Dose for ExpansionAdvanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Squamous Cell Carcinoma of Head and Neck, Non Small Cell Lung Cancer, Small-cell Lung Cancer, Bladder Cancer, Sarcoma, Endometrial Cancer, Melanoma, Castration Resistant Prostatic Cancer, Cervical Cancer, Colorectal Cancer, Gastric Cancer, Gastro-esophageal Cancer, Pancreas Cancer, Clear Cell Renal Cell Carcinoma, Hepatocellular Carcinoma, Platinum-resistant Ovarian Cancer, Breast Cancer, Ovarian Cancer, Esophageal Squamous Cell Cancer (SCC)2502024-03-06May 2028≤ 650 d2026-08-11
PMVPPMV Pharmaceuticals, Inc$66MThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)NCT04585750Phase 1 Monotherapy (Dose Escalation): Determine the number and type of adverse events to characterize the safety of rezatapoptPhase 1/2RecruitingDrug: rezatapopt, pembrolizumabAdvanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor, Lung Cancer, Ovarian Cancer, Endometrial Cancer, Prostate Cancer, Colorectal Cancer, Breast Cancer, Other Cancer, Locally Advanced, Head and Neck Cancer, Gall Bladder Cancer, Small Cell Lung Cancer, Small Cell Lung Cancer ( SCLC ), Small Cell Lung Carcinoma, NSCLC, NSCLC (Non-small Cell Lung Cancer), SCLC, Non-Small Cell Lung Carcinoma, Triple Negative Breast Cancer, TNBC, HER2+ Breast Cancer, Non-Small Cell Lung Cancer, ER/PR Positive Breast Cancer, HER2- Breast Cancer, HER2-positive Breast Cancer, HER2-negative Breast Cancer, ER/PR(+), Her2(-) Breast Cancer3002020-10-292026-08-152026-08-10
4568.TDaiichi Sankyo$31.7BA Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid TumorsNCT06172478Number of Participants With Objective Response Rate Assessed by Investigator Following HER3-DXd Monotherapy (All Cohorts Except Prostate Cancer Cohort)Phase 2RecruitingDrug: HER3-DXdAdvanced Solid Tumor, Melanoma, Head and Neck Cancer, Gastric Cancer, Ovarian Carcinoma, Cervical Cancer, Endometrial Cancer, Bladder Cancer, Esophageal Cancer, Pancreatic Carcinoma, Prostate Cancer, Non-small Cell Lung Cancer (NSCLC), Lung Cancer, Breast Cancer7402024-02-262027-09-01in 377 d2026-08-10
AVBPArriVent BioPharma, Inc.$1.5BPhase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer.NCT07755436Treatment-Emergent Adverse Event (TEAE)Phase 1RecruitingDrug: ARR-002Ovarian Cancer, Endometrial Cancer, Platinum-resistant Ovarian Cancer (PROC), Metastatic Ovarian Cancer, Metastatic Endometrial Cancer1802026-07-23Aug 2027≤ 376 d2026-08-10
051910.KSLG Chem$13.7BA Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C MutationNCT07752875Phase 1: Number of participants with dose-limiting toxicities (DLTs)Phase 1/2Not yet recruitingDrug: LG00313112Ovarian Cancer, Small Cell Lung Cancer, Non Small Cell Lung Cancer, Colorectal Cancer, Esophageal Cancer, Breast Cancer, Endometrial Cancer, Head and Neck Cancer, Pancreatic Cancer, Locally Advanced Unresectable or Metastatic Solid Tumor2502026-12-012032-10-31in 2,264 d2026-08-07
NVCTNuvectis Pharma, Inc.$681MA Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian CancerNCT05226507Part A: Number of patients with treatment related adverse events, clinical laboratory abnormalities, dose limiting toxicitiesPhase 1Terminatedsponsor's stated reason: Study terminated due to various reasons impacting the feasibility of future clinical developmentDrug: NXP800Advanced Solid Tumor, Ovarian Cancer, Ovarian Clear Cell Carcinoma, Ovarian Clear Cell Tumor, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Endometrioid Tumor, ARID1A Gene Mutation452021-12-312025-01-01actual2026-08-06
AZNAstraZenecaA Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H MutationNCT05877599Module 1, Part 1: Safety of NT-175 in participants with unresectable, advanced, and/or metastatic solid tumoursPhase 1RecruitingBiological: NT-175Non-small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Carcinoma, Pancreatic Adenocarcinoma, Breast Cancer, Other Solid Tumors, Ovarian Cancer, Myeloid Neoplasms (AML/MDS)452023-07-122029-07-31in 1,076 d2026-08-06
INCYIncyte Corporation$24.7BA Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 OverexpressionNCT07023627Objective Response by IRCPhase 2RecruitingDrug: INCB123667Ovarian Cancer1602025-11-122027-04-27in 250 d2026-08-06
LLYEli Lilly and Company$1.15TA Study of LY4337713 in Participants With FAP-Positive Solid TumorsNCT07213791Phase 1a: Percentage of Participants with Dose Limited Toxicity (DLT) ToxicitiesPhase 1RecruitingDrug: LY4337713Ovarian Neoplasms, Breast Neoplasms, Pancreatic Intraductal Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms, Stomach Neoplasms, Cholangiocarcinoma2412025-10-22Jul 2028≤ 711 d2026-08-06
LLYEli Lilly and Company$1.15TA Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian CancerNCT07213804Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 by InvestigatorPhase 3RecruitingDrug: Sofetabart Mipitecan, Paclitaxel, Topotecan, Gemcitabine, Pegylated liposomal doxorubicin (PLD), MIRV, Bevacizumab, CarboplatinOvarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Neoplasm Metastasis1,6302025-10-22Nov 2028≤ 833 d2026-08-06
INCYIncyte Corporation$24.7BStudy to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 OverexpressionNCT07214779Progression-Free Survival (PFS) by BICRPhase 3RecruitingDrug: INCB123667, Investigator's choice of chemotherapyOvarian Cancer4662025-12-092028-11-15in 818 d2026-08-06
AZNAstraZenecaStudy to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian CancerNCT01081951results2012-12-10Progression Free Survival (PFS)Phase 2Active, not recruitingDrug: olaparib, paclitaxel, carboplatin, paclitaxel, Drug: carboplatinOvarian Cancer1622010-02-042011-10-10actual2026-08-05
LLYEli Lilly and Company$1.15TA Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid TumorsNCT06465069Phase 1a: To determine the recommended phase 2 dose (RP2D) optimal dose(s) of LY4052031Phase 1RecruitingDrug: LY4052031Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm, Triple Negative Breast Cancer, Non-small Cell Lung Cancer, Esophageal Cancer, Pancreatic Cancer, Ovarian Cancer, Cervical Cancer, Head and Neck Squamous Cell Carcinoma, Prostate Cancer, Renal Pelvis Cancer, Bladder Cancer4202024-07-01May 2027≤ 284 d2026-08-05
WHWKWhitehawk Therapeutics, Inc.$271MStudy Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid TumorsNCT07444814Determine Maximum Tolerated Dose (MTD)Phase 1RecruitingDrug: HWK-007Endometrial Cancer, Ovarian Cancer, Ovarian Cancer Metastatic, Ovarian Cancer Metastatic Recurrent, Non-squamous EGFR Wt NSCLC, Platinum Resistant Ovarian Cancer, PROC2262025-12-19Oct 2028≤ 803 d2026-08-05
VSTMVerastem, Inc.$673MContinued Access to Avutometinib in Combination With Defactinib in Patients With Recurrent Low-Grade Serous Ovarian Cancer (LGSOC)NCT07747506Duration of Treatment Exposure to Avutometinib in Combination With DefactinibPhase 2Not yet recruitingDrug: avutometinib + defactininb combinationLow Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer22026-08-032027-08-01in 346 d2026-08-05
IMNNImunon$9MPhase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal CancerNCT05739981Minimal Residual DiseasePhase 1/2RecruitingDrug: Paclitaxel, Carboplatin, Bevacizumab, IMNN-001Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer302023-02-102027-06-30in 314 d2026-08-04
IMNNImunon$9MPhase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal CancerNCT06915025Overall SurvivalPhase 3RecruitingDrug: IMNN-001 (IL-12 Plasmid Formulated with PEG-PEI-Cholesterol Lipopolymer), Paclitaxel, Carboplatin, Olaparib, NiraparibEpithelial Ovarian Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma5002025-07-092032-10-31in 2,264 d2026-08-04
ABBVAbbVie$457.5BA Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian CancerNCT07059845Substudy 1, 2, and 3: Number of Participants with Treatment-Emergent Adverse Events (TEAEs) (any grade, Grade >= 3)Phase 2RecruitingDrug: Mirvetuximab Soravtansine, Bevacizumab, CarboplatinOvarian Cancer4002025-11-13Jan 2029≤ 895 d2026-08-04
AZNAstraZenecaObservational, Bi-directional (Prospective and Retrospective) Study for Patients With Newly Diagnosed Ovarian Cancer Stages IA to IVB, or Persistent or Recurrent Disease From January 2021; Irrespective of HistologyNCT07167433observationalDescription of socio-demographic characteristicsRecruitingOvarian Cancer2502025-09-192027-06-30in 314 d2026-08-04
ABBVAbbVie$457.5BStudy to Assess Prevalence of the Folate Receptor Alpha (FRa) in Adult Female Participants With Ovarian Cancer in Intercontinental (InterCon) CountriesNCT07539844observationalFolate Receptor Alpha (FRa) Overexpression Immunohistochemistry (IHC)in Each Participating Sites (Local and Central)RecruitingOvarian Cancer1,0002026-07-02Mar 2027≤ 223 d2026-07-31
ALLRAllarity Therapeutics$21MClinical Pre-screening Protocol for Ovarian CancerNCT03877796observationalIdentification of ovarian cancer patients with high likelihood of being sensitive to investigational cancer drugRecruitingDevice: Drug Response Predictor® (DRP)Ovarian Cancer602019-04-11Jun 2027≤ 314 d2026-07-30
RCUSArcus Biosciences, Inc.$3.8BStudy of AB598 Monotherapy and Combination Therapy in Participants With Advanced CancersNCT05891171Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs)Phase 1Active, not recruitingDrug: AB598, Zimberelimab, Fluorouracil, Leucovorin, OxaliplatinAdvanced Cancer, Advanced Malignancies, Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer, Gastroesophageal-junction Cancer (GEJ), Head and Neck Squamous Cell Carcinoma (HNSCC), Non-Small Cell Lung Cancer (NSCLC), Ovarian Cancer, Renal Cell Carcinoma (RCC), Triple Negative Breast Cancer (TNBC)402023-10-13Sep 2027≤ 406 d2026-07-30
AZNAstraZenecaOlaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum ChemotherapyNCT01874353results2018-02-07Progression Free Survival (PFS) Using Investigator Assessment According to Modified Response Evaluation Criteria In Solid Tumours (RECIST 1.1)Phase 3Active, not recruitingDrug: Olaparib 300mg tablets, Placebo to match olaparib 300mgPlatinum Sensitive, BRCA Mutated, Relapsed Ovarian Cancer, Following Complete or Partial Response to Platinum Based Chemotherapy3272013-09-032016-09-19actual2026-07-29
ABBVAbbVie$457.5BA Study to Evaluate Folate Receptor Alpha (FRα) Expression in Adult Participants With Ovarian, Fallopian Tube, and Primary Peritoneal Cancer in ItalyNCT07407062observationalFRα - Positive StatusRecruitingCancer - Ovarian2002026-06-26Nov 2026≤ 102 d2026-07-27
AAPGAscentage Pharma Group Inc.APG-2449 in Patients With Advanced Solid TumorsNCT03917043Maximum Tolerated Dose (MTD)Phase 1RecruitingDrug: APG-2449Advanced Solid Cancer, Non Small Cell Lung Cancer, Esophageal Cancer, Ovarian Cancer, Malignant Pleural Mesothelioma1652019-05-27Dec 2027≤ 498 d2026-07-23
AZNAstraZeneca'OLAP' (OLAparib Regulatory Post-marketing Surveillance)NCT04553926observationalSafety (adverse events (AEs), serious AEs (SAEs), adverse drug reactions(ADRs), serious ADRs (SADRs), unexpected AEs/ADRs)CompletedOvarian Cancer, Breast Cancer, Prostate Cancer, Pancreatic Cancer6612021-02-012025-07-11actual2026-07-23
AZNAstraZenecaPhase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid TumorsNCT05797168Number of participants with adverse events/serious adverse eventsPhase 1/2RecruitingDrug: Torvutatug samrotecan, Saruparib, Bevacizumab, Carboplatin, Palacaparib, PembrolizumabOvarian Cancer, Lung Adenocarcinoma, Endometrial Cancer, Lung Squamous Cell Carcinoma6022023-06-052028-08-04in 715 d2026-07-23
REGNRegeneron Pharmaceuticals$76.1BStudy of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) CancersNCT03564340Number of participants with Dose-limiting toxicity (DLTs) for ubamatamab monotherapyPhase 1/2RecruitingDrug: Ubamatamab, Cemiplimab, Sarilumab, TocilizumabRecurrent Ovarian Cancer, Recurrent Fallopian Tube Cancer, Recurrent Primary Peritoneal Cancer, Recurrent Endometrial Cancer, Endometrial Cancer, Low-grade Serous Ovarian Cancer8902018-05-212027-05-10in 263 d2026-07-22
PFESeagen, a wholly owned subsidiary of Pfizer$155.3BA Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2NCT06003231Confirmed Objective Response Rate (ORR) per Response Evaluation in Solid Tumors version 1.1 (RECIST v1.1) by investigator assessmentPhase 2Active, not recruitingDrug: disitamab vedotinCarcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Endometrial Neoplasms, Head and Neck Neoplasms1202023-11-142026-03-27actual2026-07-22
AZNAstraZenecaDESTINY-PANTUMOUR04NCT07124000observationalReal world response rate (rwRR)RecruitingDrug: Trastuzumab deruxtecanAdenocarcinoma (NOS), Anal Cancer, Bladder Cancer, Cervical Cancer, Endometrial Cancer, Esophageal Cancer, Gall Bladder Cancer, Gastrointestinal Stromal Tumour, Head and Neck Cancer, Liver Cancer, Melanoma, Mouth Cancer, Nasopharangeal Cancer, Neuroendocrine, Gastrointestinal Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Renal Cell Carcinoma, Salivary Gland Cancer, Sarcoma, Small Cell Lung Cancer, Testicular Cancer, Throat Cancer, Thyroid Cancer, Urethral Cancer, Vaginal Cancer, Vulvar Cancer1002025-09-182028-03-30in 588 d2026-07-22
AZNAstraZenecaAZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian CancerNCT07218809Progression free Survival (PFS)Phase 3RecruitingDrug: AZD5335, Mirvetuximab Soravtansine (MIRV), Paclitaxel, Pegylated liposomal Doxorubicin (PLD), TopotecanEpithelial Ovarian Cancer1,1002025-12-292028-11-17in 820 d2026-07-21
RADXRadiopharm Theranostics, LtdSafety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid TumorsNCT05799274Radiation dosimetry of RAD301Phase 1RecruitingDrug: RAD301 ([68Ga]-RAD301)Healthy Volunteers, Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer (NSCLC), Esophageal Squamous Cell Carcinoma, Cervical Cancer, Endometrial Cancer, Ovarian Cancer92023-11-09Aug 2026≤ 11 d2026-07-17
CORTCorcept Therapeutics$12.8BRelacorilant in Combination With Different Treatment Regimens in Patients With Gynecological CancersNCT06906341Progression-Free Survival (PFS)Phase 2RecruitingDrug: Relacorilant 150 mg once daily (QD), Nab-paclitaxel 80 mg/m^2, Bevacizumab 10 mg/kgOvarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms, Endometrial Cancer2702025-04-11Aug 2026≤ 11 d2026-07-16
ABBVAbbVie$457.5BA Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Bevacizumab in Adult Participants With Ovarian CancerNCT07278336Number of Participants with Adverse Events (AE)Phase 1RecruitingDrug: ABBV-901, BevacizumabOvarian Cancer2192025-11-27Jan 2029≤ 895 d2026-07-15
IDYAIDEAYA Biosciences$3.7BA Study of PARG Inhibitor IDE161 in Participants With Advanced Solid TumorsNCT05787587Part 1 (Dose Escalation): To characterize the safety and tolerability of IDE161 monotherapy or in combination with pembrolizumab to determine the MTD and/or RDEPhase 1Active, not recruitingDrug: IDE-161, PembrolizumabAdvanced or Metastatic Solid Tumors, Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, Colorectal Cancer, Head and Neck Cancers, Extensive Stage Small Cell Lung Cancer (ES-SCLC), NSCLC2162023-04-18Oct 2026≤ 72 d2026-07-13
AZNAstraZenecaNon-interventional Study to Collect Real-world Clinical and Patient-reported Outcomes in Ovarian CancerNCT04830709observationalprogression-free survival (PFS)Active, not recruitingOvarian Cancer7522021-06-152033-03-31in 2,415 d2026-07-10
GNLXGenelux Corporation$118MEfficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)NCT05281471Progression-free survival (PFS) by RECIST 1.1 in the Intention-to-Treat (ITT) population (all randomized participants regardless of whether they received any dose of treatment)Phase 3RecruitingBiological: olvimulogene nanivacirepvec · Drug: Platinum chemotherapy: carboplatin (preferred) or cisplatin, Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin, Bevacizumab (or biosimilar)Platinum-resistant Ovarian Cancer, Platinum-refractory Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, High-grade Serous Ovarian Cancer, Endometrioid Ovarian Cancer, Ovarian Clear Cell Carcinoma1862022-08-31Dec 2026≤ 133 d2026-07-10
JAZZJazz Pharmaceuticals$16.4BA Phase 2 Study of Zanidatamab in Patients With HER2-expressing TumorsNCT06695845Confirmed Objective Response Rate (cORR) per RECIST Version 1.1, as assessed by ICRPhase 2RecruitingDrug: ZanidatamabBreast Cancer, Gastric Cancer, Esophageal Cancer, Gastroesophageal Cancer, Colorectal Cancer, Endometrial Cancer, Non-small Cell Lung Cancer, Ovarian Cancer, Urothelial Carcinoma, Salivary Gland Cancer, Pancreatic Cancer, HER-2 Protein Overexpression2002025-01-142026-12-31in 133 d2026-07-10
BMYBristol-Myers Squibb$134.9BA Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid TumorsNCT06997029Number of Participants With Dose Limiting Toxicities (DLTs)Phase 1RecruitingDrug: BMS-986500, Palbociclib, FulvestrantAdvanced Solid Tumor, Advanced Breast Cancer, Advanced Ovarian Cancer2342025-08-012028-12-14in 847 d2026-07-10
LLYEli Lilly and Company$1.15TA Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid TumorsNCT02009449results2026-07-09Number of Participants With TEAEs and SAEs Observed During the Study of PegilodecakinPhase 1CompletedDrug: Pegilodecakin, Paclitaxel or Docetaxel and Carboplatin or Cisplatin, FOLFOX (Oxaliplatin/Leucovorin/5-Fluorouracil), gemcitabine/nab-paclitaxel, Capecitabine, Pazopanib, Pembrolizumab, Paclitaxel, nivolumab, Gemcitabine/carboplatinMelanoma, Prostate Cancer, Ovarian Cancer, Renal Cell Carcinoma, Colorectal Carcinoma, Pancreatic Carcinoma, Non-small Cell Lung Carcinoma, Solid Tumors, Breast Cancer3532013-11-152019-02-19actual2026-07-09
AZNAstraZenecaDrug Intensive Monitoring Study of Olaparib in Clinical Practice Among Chinese PatientsNCT04560452observationalNumber and percentage of patients with AEs as well as number of AE events as assessed by CTCAECompletedOvarian Cancer, Prostate Cancer1,0182021-03-152025-09-05actual2026-07-08
AZNAstraZenecaDurvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer PatientsNCT03737643results2026-06-09Progression-free Survival (PFS) by Investigator Assessment Using Modified RECIST 1.1 - Full Analysis SetPhase 3Active, not recruitingDrug: Bevacizumab, Durvalumab, Olaparib, Placebo olaparib, Durvalumab placebo, Carboplatin+PaclitaxelAdvanced Ovarian Cancer1,4072019-01-042025-03-17actual2026-07-07
PFESeagen, a wholly owned subsidiary of Pfizer$155.3BA Study of SGN-MesoC2 in Advanced Solid TumorsNCT06466187Number of participants with adverse events (AEs)Phase 1Terminatedsponsor's stated reason: The trial was terminated for strategic reasons. The decision was not based on any safety concernsDrug: PF-08052666Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Adenocarcinoma, Colorectal Neoplasms, Mesothelioma, Other Solid Tumors, Endometrial192024-08-022026-05-27actual2026-07-07
AZNAstraZenecaDrug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube CancerNCT07402915Area under curve from time 0 to time 17 days (AUC0-17days)Phase 1RecruitingDrug: AZD5335, ItraconazoleFallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal242026-01-262027-10-15in 421 d2026-07-07
PFESeagen, a wholly owned subsidiary of Pfizer$155.3BA Study of Sigvotatug Vedotin in Advanced Solid TumorsNCT04389632Number of participants with adverse events (AEs)Phase 1RecruitingDrug: sigvotatug vedotin, pembrolizumab, cisplatin, carboplatinCarcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, HER2 Negative Breast Neoplasms, Esophageal Squamous Cell Carcinoma, Esophageal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Ovarian Neoplasms, Cutaneous Squamous Cell Cancer, Exocrine Pancreatic Adenocarcinoma, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Stomach Neoplasms1,0062020-06-082027-06-16in 300 d2026-07-06
CATXPerspective Therapeutics$366MLead-212 PSV359 Therapy for Patients With Solid TumorsNCT06710756Determination of safety and tolerability of [203Pb]Pb-PSV359Phase 1/2RecruitingDrug: [203Pb]Pb-PSV359, [212Pb]Pb-PSV359Pancreatic Ductal Adenocarcinoma, Gastric Cancer, Esophageal Cancer, Colorectal Cancer, Ovarian Cancer, Head and Neck Cancer, Sarcoma, Mesothelioma1122025-04-282028-01-31in 529 d2026-07-06
4568.TDaiichi Sankyo$31.7BStudy of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)NCT06819007Progression Free Survival by Blinded Independent Central Review (BICR) in the HER2 IHC 3+/2+ populationPhase 3RecruitingDrug: Trastuzumab Deruxtecan, BevacizumabOvarian Cancer5822025-03-192028-11-01in 804 d2026-07-02
IBRXImmunityBio, Inc.$8.2BA Phase 2, Open-label, Single-arm Study Of Autologous M-CENK Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High-Grade Ovarian CancerNCT06710288Evaluate Progression Free Survival (PFS)Phase 2RecruitingDrug: Gemcitabine · Biological: N-803, M-CENKPlatinum-resistant Ovarian Cancer202024-11-06May 2027≤ 284 d2026-07-01
3402.TToray Industries, Inc$12.6BA Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid TumorsNCT03872947Frequency of patients experiencing treatment emergent adverse events as assessed by CTCAE v5.0Phase 1Active, not recruitingBiological: TRK-950, TRK-950, TRK-950 · Drug: Irinotecan, Leucovorin, 5-FU, Gemcitabine, Cisplatin, Carboplatin, Ramucirumab, Paclitaxel, Nivolumab, Pembrolizumab, Imiquimod Cream, Bevacizumab, PLDSolid Tumor, Colorectal Cancer, Cholangiocarcinoma, Bladder Cancer, Ovarian Cancer, Gastric Cancer, Palpable Subcutaneous Malignant Lesions, Renal Cell Carcinoma, Melanoma, Epithelial Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer1382019-04-26Jun 20262026-06-23
ABBVAbbVie$457.5BStudy to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab AdizutecanNCT05005403Number of Participants with Adverse Events (AE)Phase 1RecruitingDrug: Azirkitug, Budigalimab, Bevacizumab, Telisotuzumab AdizutecanNon-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Micro Satellite Stable Colorectal Cancer, Gastric/Esophageal Cancer, High-Grade Serous Ovarian Cancer, Pancreatic Cancer, Triple Negative Breast Cancer6942021-11-01Jul 2027≤ 345 d2026-06-23
PFEPfizer$155.3BContinued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are ClosingNCT05059522Number of participants with adverse events leading to permanent discontinuation of study interventionPhase 3Active, not recruitingDrug: Avelumab, Lorlatanib, Talazoparib, Pemetrexed, Axitinib, CMP 001, Utomilumab, PF04518600Advanced Malignancies, NSCLC, Ovarian Cancer, Urothelial Cancer, Solid Tumors772021-09-292026-12-31in 133 d2026-06-22
LLYEli Lilly and Company$1.15TA Study of LY4170156 in Participants With Selected Advanced Solid TumorsNCT06400472Phase 1a: To determine the recommended phase 2 dose (RP2D) of LY4170156Phase 1RecruitingDrug: LY4170156, bevacizumab, carboplatin, Itraconazole, pembrolizumabOvarian Neoplasms, Endometrial Neoplasms, Uterine Cervical Neoplasms, Carcinoma, Non-Small-Cell Lung, Triple Negative Breast Neoplasms, Pancreatic Neoplasm, Colorectal Neoplasms4952024-05-20Feb 2027≤ 192 d2026-06-18
IDYAIDEAYA Biosciences$3.7BA Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors TypesNCT07503808Safety and tolerability of IDE034 in Part 1 dose escalationPhase 1RecruitingDrug: IDE034Esophageal Squamous Cell Carcinoma, High Grade Serous Ovarian Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Cancer, Castration-resistant Prostate Cancer, Non Small Cell Lung Cancer, Endometrium Cancer, Triple Negative Breast Cancer1502026-02-242027-07-30in 344 d2026-06-18
CNTXContext Therapeutics Inc.$49MA Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid TumorsNCT06515613Incidence of Dose Limiting Toxicities (DLTs)Phase 1RecruitingDrug: CTIM-76Platinum-resistant Ovarian Cancer, Testicular Cancer, Endometrial Cancer1562024-07-102028-05-31in 650 d2026-06-16
GNLXGenelux Corporation$118MOlvi-Vec Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian CancerNCT02759588results2026-06-12Number of Participants With Related Treatment-emergent Adverse Event [Safety and Tolerability] (Phase 1b)Phase 1/2CompletedBiological: Olvi-Vec · Drug: Platinum-doublet with or without bevacizumabOvarian Cancer, Peritoneal Carcinomatosis, Fallopian Tube Cancer46May 20162021-12-31actual2026-06-12
AZNAstraZenecaRoll Over StudY for Patients Who Have Completed a Previous Oncology Study With OlaparibNCT04421963Safety follow upPhase 3Active, not recruitingDrug: OlaparibOvarian Cancer, Breast Cancer1852020-08-042027-04-06in 229 d2026-06-12
ABBVAbbVie$457.5BA Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha ExpressionNCT06365853Number of Participants With MIRV-related Corneal TEAEs (≥ Grade 2) in Asymptomatic ParticipantsPhase 2RecruitingDrug: Mirvetuximab Soravtansine, Lubricating Eye Drops, Prednisolone acetate ophthalmic suspension 1% eye drops, Brimonidine tartrate ophthalmic solution eye dropsRecurrent Ovarian Cancer, Folate Receptor-Alpha Positive1002024-07-29Jun 20262026-06-12
CNTXContext Therapeutics Inc.$49MCT-95 in Advanced Cancers Associated With Mesothelin ExpressionNCT06756035Determine the MTD or RD of CT-95 [Safety and Tolerability]Phase 1RecruitingDrug: CT-95Mesothelin-Expressing Tumors, Epithelial Ovarian Cancer, Malignant Pleural Mesothelioma, Advanced, Malignant Peritoneal Mesothelioma, Advanced, Pancreatic Adenocarcinoma Advanced or Metastatic, Lung Adenocarcinoma Metastatic, Cholangiocarcinoma Advanced, Cholangiocarcinoma Non-resectable, Mesothelin-expressing Advanced Cancers, Mesothelin-positive Advanced Malignant Solid Tumors, Colorectal Cancer702025-03-31Dec 2026≤ 133 d2026-06-12
XNCRXencor, Inc.$1.9BPhase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid TumorsNCT06276491Incidence of adverse eventsPhase 1RecruitingBiological: XmAb541Ovarian Cancer, Endometrial Cancer, Germ Cell Tumor, Testicular Germ Cell Tumor, Ovarian Germ Cell Tumor2822024-04-04Dec 2027≤ 498 d2026-06-11
RXRXExscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.$1.7BDose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid TumorsNCT07517198Number of Participants With Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs)Phase 1RecruitingDrug: EXS74539Solid Tumor, Small Cell Lung Cancer (SCLC), High Grade Neuroendocrine Cancer, Small Cell Carcinomas of Non-lung Origin, Non-small Cell Lung Cancer (NSCLC), Prostate Cancer, Ovarian Cancer, Renal Carcinoma (Clear and Non-clear Cell), Head and Neck Squamous Cell Carcinoma (HNSCC), Hepatic Cancer, Gastric Cancer, Triple-negative Breast Cancer (TNBC)402026-04-13Mar 2029≤ 954 d2026-06-10
PFEPfizer$155.3BStudy to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.NCT04881045Number of participants with dose limiting toxicities (DLTs) in Dose Escalation (Part 1)Phase 1CompletedBiological: PF-07257876Non-Small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Ovarian Cancer292021-08-182023-10-24actual2026-06-02
ABBVAbbVie$457.5BMirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal CancerNCT05445778Assess Progression-free survival (PFS)Phase 3Active, not recruitingDrug: Mirvetuximab soravtansine plus Bevacizumab, BevacizumabOvarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer5202023-03-15Apr 2027≤ 253 d2026-06-02
MGNXMacroGenics$261MA Study of Lorigerlimab in Participants With Advanced Solid TumorsNCT06730347Objective Response Rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria as determined by the investigatorPhase 2RecruitingBiological: LorigerlimabPlatinum-resistant Ovarian Cancer, Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Clear Cell Adenocarcinoma of Ovary, Clear Cell Adenocarcinoma of Vulva, Clear Cell Adenocarcinoma of Vagina, Clear Cell Adenocarcinoma of Cervix, Clear Cell Adenocarcinoma of Uterus, Clear Cell Adenocarcinoma of Fallopian Tube, Clear Cell Adenocarcinoma of Peritoneum, Endometrial Cancer802025-05-01Jul 2027≤ 345 d2026-06-02
LLYEli Lilly and Company$1.15TStudy of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)NCT04956640Phase 1a: To determine the recommended phase 2 dose (RP2D) of LY3537982 monotherapyPhase 1/2Active, not recruitingDrug: LY3537982, Pembrolizumab, Cetuximab, Pemetrexed, Cisplatin, CarboplatinCarcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Endometrial Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Biliary Tract Neoplasms5402021-07-19Apr 2027≤ 253 d2026-05-29
AZNAstraZenecaA Non-interventional Prospective Study of 1-st Line Treatment Approaches in OVArian Cancer Patients With HRD+ Status in Russian FederationNCT05918042observationalTo describe the demographic and clinical characteristics of the patient population with HRD-positive OC (HRD+ BRCAwt and HRD+ BRCAm)CompletedOvarian Cancer4142023-06-212025-05-29actual2026-05-28
LLYEli Lilly and Company$1.15TA Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid TumorsNCT06238479Phase 1a: To determine the recommended dose of LY4101174Phase 1Active, not recruitingDrug: LY4101174Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm, Triple Negative Breast Cancer, Non-small Cell Lung Cancer, Esophageal Cancer, Pancreatic Cancer, Ovarian Cancer, Cervical Cancer, Head and Neck Squamous Cell Carcinoma, Prostate Cancer, Renal Pelvis Cancer, Bladder Cancer4902024-03-05Mar 2027≤ 223 d2026-05-22
AGENAgenus Inc.$339MExpanded Access Program (EAP) Designed to Provide Access to Botensilimab and Balstilimab Before Regulatory ApprovalNCT06751524expanded accessAvailableDrug: Botensilimab, BalstililmabColorectal Cancer (CRC), Pancreatic Cancer, Non-Small Cell Lung Cancer (NSCLC), Hepatocellular Carcinoma (HCC), Melanoma, Sarcoma, Ovarian Cancer, Prostate Cancer2026-05-15
PFEPfizer$155.3BPF-07104091 as a Single Agent and in Combination TherapyNCT04553133Dose Escalation: Number of participants with Dose-limiting toxicities (DLT) during first cyclePhase 2Active, not recruitingDrug: PF-07104091 monotherapy dose escalation, PF-07104091 + palbociclib + fulvestrant, PF-07104091 + palbociclib + letrozole, PF-07104091 monotherapy dose expansion (ovarian), PF-07104091 monotherapy dose expansion (SCLC), PF-07104091 + Fulvestrant (post CDK4/6), PF-0704091 + Fulvestrant (post CDK4/6)Small Cell Lung Cancer, Ovarian Cancer, Breast Cancer1572020-09-162026-12-31in 133 d2026-05-06
IMNNImunon$9MStudy of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)NCT03393884PFSPhase 1/2Active, not recruitingBiological: IMNN-001 · Drug: Carboplatin, PaclitaxelEpithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer1302018-09-052024-07-25actual2026-05-04
TILInstil Bio$50MITIL-306 in Advanced Solid TumorsNCT05397093Frequency and severity of ITIL-306 treatment-emergent adverse events (AEs), serious AEs, and AEs of special interest (AESI)Phase 1Terminatedsponsor's stated reason: The study was terminated early due to discontinuation of development of the investigational programBiological: ITIL-306Epithelial Ovarian Cancer, Non-small Cell Lung Cancer, Renal Cell Carcinoma12022-08-242023-10-10actual2026-04-15
AZNAstraZenecaESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid TumorsNCT06973161observationalOverall SurvivalCompletedBladder Cancer, Biliary Tract Cancer, Cervical Cancer, Endometrial Cancer, Ovarian Cancer, Pancreatic Cancer, Colorectal Cancer, Lung Cancer, Other Tumors1402025-06-102026-03-17actual2026-04-08
ZNTLK-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc$264MA Study of Azenosertib (ZN-c3) in Patients With Ovarian CancerNCT04516447Part 1: To investigate the safety and tolerability of azenosertib in combination with PLD, carboplatin, paclitaxel, or gemcitabinePhase 1RecruitingDrug: Azenosertib, Carboplatin, Pegylated liposomal doxorubicin, Paclitaxel, Gemcitabine · Biological: BevacizumabSolid Tumor, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer1722020-10-262028-06-30in 680 d2026-04-07
FATEFate Therapeutics$307MFT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid TumorsNCT07216105Number of participants with dose limiting toxicities (DLTs)Phase 1RecruitingDrug: FT836, Paclitaxel, Cetuximab, TrastuzumabNon-Small Cell Lung Cancer, Colorectal Cancer, Breast Cancer, Ovarian Cancer, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma1132025-11-04Jan 2028≤ 529 d2026-04-07
AGENAgenus Inc.$339MFc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced CancerNCT03860272Incidence Of Treatment-emergent Adverse Events (TEAEs)Phase 1Active, not recruitingDrug: Botensilimab, BalstilimabAdvanced Cancer, Angiosarcoma, Colorectal Cancer Without Liver Metastases, Endometrial Cancer, Fibrolamellar Carcinoma, Non-small-cell Lung Cancer, Ovarian Cancer, Prostate Cancer4992019-03-202025-01-13actual2026-03-30
RADXRadiopharm Theranostics, Ltd177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid TumorsNCT07189871Recommended dose(s) of 177Lu-BetaBart for future exploration (phase 1)Phase 1/2RecruitingDrug: 177Lu-BetaBartCastration-Resistant Prostate Cancer (CRPC), Colorectal Cancer, NSCLC (Non-small Cell Lung Cancer), Ovarian Cancer, Cervical Cancer, Endometrial Cancer, TNBC, Triple Negative Breast Cancer, Small Cell Lung Cancer (SCLC ), Head &Amp; Neck Squamous Cell Carcinoma (HNSCC), Esophageal Squamous Cell Carcinoma (ESCC)612026-02-23Dec 2027≤ 498 d2026-03-27
ZNTLK-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc$264MA Study of Azenosertib (ZN-c3) and Niraparib in Subjects With Platinum-Resistant Ovarian CancerNCT05198804To investigate the safety and tolerability of ZN-c3 in combination with niraparib, including identification of the MTD and RP2DPhase 1/2CompletedDrug: Azenosertib, NiraparibOvarian Cancer, Platinum-resistant Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer1172022-01-272025-10-15actual2026-03-18
AZNAstraZenecaD9319C00001- 1L OC Mono Global RCTNCT04884360Superiority of olaparib as maintenance treatment relative to placebo by assessment of PFS in participants with Stage III/IV ovarian cancer with a BRCAwt HRD positive tumour and a CR/PR following standard 1st line platinum based chemotherapy treatment.Phase 3Active, not recruitingDrug: Olaparib · Other: Matching placeboOvarian Cancer3662021-05-312026-07-272026-03-02
PFEPfizer$155.3BA Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.NCT06546553PART 1: Number of participants with Dose-limiting toxicities (DLT)Phase 1Terminatedsponsor's stated reason: Study terminated as part of strategic considerations and not based on safety concerns.Drug: PF-07826390 · Biological: sasanlimab · Other: SOC (anti-PD-1 + platinum -based chemo)Neoplasms, Non-small-cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Renal Cell Carcinoma, Colorectal Carcinoma, Ovarian Carcinoma102024-09-062025-10-03actual2026-02-23
REGNRegeneron Pharmaceuticals$76.1BA Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian CancersNCT06469281Incidence of treatment emergent adverse events (TEAEs)Phase 1RecruitingOther: 27T51 · Drug: Cemiplimab, BevacizumabEpithelial Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer902024-08-062030-05-27in 1,376 d2026-02-03
CUECue Biopharma$2.4BA Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic CancersNCT05360680Dose Limiting ToxicityPhase 1CompletedDrug: CUE-102Colorectal Cancer, Gastric Cancer, Pancreatic Cancer, Ovarian Cancer422022-06-142025-03-12actual2026-01-22
NTRANatera, Inc.$44.9BSample Collection for Ongoing Research and Product Evaluation StudyNCT07318051observationalPrimary Outcome - Collection of Blood and Residual Tissue Specimens for Cancer Assay DevelopmentRecruitingBreast Cancer, Lung Cancer, Muscle Invasive Bladder Cancer, Rectal Cancer, Pancreatic Cancer, Ovarian Cancer, Gastroesophageal Cancer, Prostate Cancer, Melanoma, Head and Neck Cancer, Uterine Cancer, Liver Cancer9,6002025-07-21Jan 2035≤ 3,086 d2026-01-15
NUVBNuvation Bio Inc.$2.4BSafety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid TumorsNCT06334432Phase 1: Assess safety and tolerability of NUV-1511 in advanced solid tumorsPhase 1/2Active, not recruitingDrug: NUV-1511Advanced Solid Tumor, HER2-negative Breast Cancer, Metastatic Castration-resistant Prostate Cancer (mCRPC), Pancreatic Cancer, Platinum-resistant Ovarian Cancer (PROC)4662024-03-14Mar 2027≤ 223 d2026-01-14
ABBVAbbVie$457.5BMirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube CancersNCT05041257results2026-01-09Objective Response Rate (ORR) Assessed by Investigator Per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1])Phase 2CompletedDrug: Mirvetuximab soravtansineOvarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer792021-10-192024-12-12actual2026-01-09
PFESeagen, a wholly owned subsidiary of Pfizer$155.3BA Study of Felmetatug Vedotin/SGN-B7H4V in Advanced Solid TumorsNCT05194072Number of participants with adverse events (AEs)Phase 1Terminatedsponsor's stated reason: The trial was terminated for strategic reasons. The decision was not based on any safety and/or efficacy concernsDrug: Felmetatug Vedotin, PembrolizumabOvarian Neoplasms, Peritoneal Neoplasms, Fallopian Tube Neoplasms, Triple Negative Breast Neoplasms, HER2 Negative Breast Neoplasms, Hormone Receptor Positive Breast Neoplasms, Endometrial Neoplasms, Carcinoma, Non-Small-Cell Lung, Cholangiocarcinoma, Gallbladder Carcinoma, Adenoid Cystic Carcinoma2502022-01-122025-05-14actual2026-01-09
STTKShattuck Labs, Inc.$748MPhase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian CancersNCT05483933results2025-12-23Evaluate Safety and Tolerability of SL-172154 When Administered With PLD or MirvetixumabPhase 1CompletedDrug: Pegylated Liposomal Doxorubicin + SL-172154, Mirvetuximab + SL-172154Platinum-resistant Ovarian Cancer, Fallopian Tube Cancer, Epithelial Ovarian Cancer, Ovarian Cancer, Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Primary Peritoneal Carcinoma862022-08-182025-02-07actual2025-12-23
VSTMVerastem, Inc.$673MA Study of Avutometinib + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer in Japanese PatientsNCT06682572Confirmed overall response rate (ORR; partial response [PR] + complete response [CR]Phase 2Active, not recruitingDrug: Avutometinib (VS-6766) + Defactinib (VS-6063)Low Grade Serous Ovarian Cancer, Ovarian Cancer162024-10-30Dec 20252025-12-17

Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.

How Ovarian Cancer is matched — 26 exact registry spellings

A study is on this page when its ClinicalTrials.gov record names one of these conditions exactly (letter case aside). Nothing is matched by substring or stem, so a longer condition that merely contains one of these words is a different page. The list was curated by hand and last measured 2026-08-19; a spelling filed by only one study was not curated, so the counts here are a floor rather than the registry's own total for the disease.

  • Ovarian Cancer
  • Ovarian Neoplasms
  • Epithelial Ovarian Cancer
  • Ovarian Carcinoma
  • Platinum-resistant Ovarian Cancer
  • Advanced Ovarian Cancer
  • Ovary Cancer
  • Ovarian Clear Cell Carcinoma
  • High Grade Serous Ovarian Cancer
  • High Grade Serous Ovarian Carcinoma
  • High-grade Serous Ovarian Cancer
  • Ovarian Cancer, Epithelial
  • Ovarian Epithelial Cancer
  • Ovarian Neoplasm
  • Ovary Neoplasm
  • Platinum Resistant Ovarian Cancer
  • Recurrent Ovarian Cancer
  • Cancer - Ovarian
  • Cancer of the Ovary
  • Epithelial Ovarian Carcinoma
  • Low Grade Ovarian Serous Adenocarcinoma
  • Low Grade Serous Ovarian Cancer
  • Low-grade Serous Ovarian Cancer
  • Platinum-resistant Ovarian Cancer (PROC)
  • Relapsed Ovarian Cancer
  • Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity

Permalink · All conditions · Catalyst calendar · Every registered study · Search the whole pipeline for “Ovarian Cancer” (a text search, wider than this page)