Gingivitis trial readouts
registry pull 2026-08-19Primary-completion dates that listed drug and biotech companies filed with ClinicalTrials.gov for studies in Gingivitis. They are the sponsor's own estimated windows, revised as a study runs — not announcement dates. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Upcoming readout windows
next 180 days · by month5 studies across 2 companies, in the next 180 days.
September 2026 3
| Ticker | Name | Study | Phase | Status | Primary completion | Readout in | Updated |
|---|---|---|---|---|---|---|---|
| CL | Colgate Palmolive | 6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum HealthNCT07414173Improvement of gum health as measured by the Gingival Index (Löe 1967) between the study groups. | Phase 4 | Recruiting | Sep 2026 | ≤ 41 d | 2026-02-17 |
| CL | Colgate Palmolive | A Study to Investigate Stannous Fluoride Containing Toothpaste on Antibacterial Effects in the Different Regions of the MouthNCT07458464Loe-Silness | Phase 3 | Not yet recruiting | Sep 2026 | ≤ 41 d | 2026-07-28 |
| CL | Colgate Palmolive | Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High GingivitisNCT07614490Relative abundance of Streptococcus and Porphyromonas | Phase 4 | Recruiting | 2026-09-30 | in 41 d | 2026-05-29 |
October 2026 1
| Ticker | Name | Study | Phase | Status | Primary completion | Readout in | Updated |
|---|---|---|---|---|---|---|---|
| HLN | HALEON | A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival HealthNCT07704905Change from Baseline in Overall Modified Gingival Index (MGI) at Week 8 | Not applicable | Recruiting | Oct 2026 | ≤ 72 d | 2026-08-12 |
November 2026 1
| Ticker | Name | Study | Phase | Status | Primary completion | Readout in | Updated |
|---|---|---|---|---|---|---|---|
| CL | Colgate Palmolive | To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.NCT07605338Loe-Silness Gingival Index | Phase 3 | Active, not recruiting | Nov 2026 | ≤ 102 d | 2026-05-27 |
Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.
Every registered study in Gingivitis
most recently updated first68 studies match.
| Ticker | Name | Market cap | Study | Phase | Status | Interventions | Conditions | Enrollment | Start | Primary completion | Readout in | Updated |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HLN | HALEON | — | A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival HealthNCT07704905Change from Baseline in Overall Modified Gingival Index (MGI) at Week 8 | Not applicable | Recruiting | Drug: Test Dentifrice, Reference Dentifrice (Colgate Cavity Protection Dentifrice) | Dental Plaque, Gingivitis | 110 | 2026-07-13 | Oct 2026 | ≤ 72 d | 2026-08-12 |
| HLN | HALEON | — | A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque AccumulationNCT07255040Number of Bleeding Sites (Overall) at Week 24 | Not applicable | Completed | Drug: Test Dentifrice, Parodontax Complete Protection, Colgate Cavity Protection | Dental Plaque, Gingivitis | 284 | 2025-11-19 | 2026-07-30actual | — | 2026-08-05 |
| CL | Colgate Palmolive | $72.9B | The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and GingivitisNCT07224828Löe and Silness Gingival Index | Phase 3 | Completed | Drug: Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste | Plaque, Gingivitis | 130 | 2025-10-14 | 2026-01-28actual | — | 2026-07-31 |
| CL | Colgate Palmolive | $72.9B | A Study to Investigate Stannous Fluoride Containing Toothpaste on Antibacterial Effects in the Different Regions of the MouthNCT07458464Loe-Silness | Phase 3 | Not yet recruiting | Drug: stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste | Plaque, Gingivitis | 100 | Aug 2026 | Sep 2026 | ≤ 41 d | 2026-07-28 |
| CL | Colgate Palmolive | $72.9B | Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High GingivitisNCT07614490Relative abundance of Streptococcus and Porphyromonas | Phase 4 | Recruiting | Drug: sodium monofluorophosphate toothpaste | Gingivitis, Plaque | 100 | 2026-04-20 | 2026-09-30 | in 41 d | 2026-05-29 |
| CL | Colgate Palmolive | $72.9B | To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.NCT07605338Loe-Silness Gingival Index | Phase 3 | Active, not recruiting | Drug: Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste · Other: Flat Trimmed Extra Clean TB | Plaque, Dental, Gingivitis | 85 | 2026-05-11 | Nov 2026 | ≤ 102 d | 2026-05-27 |
| CL | Colgate Palmolive | $72.9B | Investigation of Clinical Efficacy of a New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems as Compared to a Control MouthwashNCT07263698Modified Gingival Index | Phase 3 | Completed | Drug: cetylpyridinium chloride (CPC), zinc lactate and sodium fluoride Mouthwash, sodium fluoride Mouthwash | Gingivitis, Plaque, Dental | 80 | 2025-12-01 | 2026-02-27actual | — | 2026-05-26 |
| PG | Procter and Gamble | $333.4B | Assessing Gingivitis of 3 Different Dentifrices Compared to a Negative Control.NCT06892834results2026-05-04Number Bleeding Sites | Phase 2 | Completed | Drug: Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, Sodium monofluorophosphate dentifrice | Gingivitis | 120 | 2025-03-25 | 2025-06-19actual | — | 2026-05-04 |
| CL | Colgate Palmolive | $72.9B | Efficacy of a Toothpaste in Reducing Plaque, Gingivitis, and Gingival BleedingNCT07499115Modified Gingival Index (MGI_ Lobene) | Phase 3 | Not yet recruiting | Drug: Toothpaste containing chitosan, Colgate Cavity Protection Toothpaste | Plaque, Dental, Gingivitis | 90 | Apr 2026 | Jul 2026 | — | 2026-04-13 |
| CL | Colgate Palmolive | $72.9B | Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.NCT06244303Quigley and Hein Plaque Index | Phase 3 | Completed | Drug: manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream | Gingivitis, Plaque | 82 | 2024-01-22 | 2024-04-16actual | — | 2026-03-19 |
| CL | Colgate Palmolive | $72.9B | The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis.NCT06427499Loe and Silness Gingival Index. | Phase 3 | Completed | Drug: Stannous fluoride toothpaste, Colgate Cavity Protection Toothpaste | Plaque, Gingivitis | 95 | 2024-04-22 | 2024-08-05actual | — | 2026-03-19 |
| CL | Colgate Palmolive | $72.9B | Investigation of Colgate Dual Zinc Toothpaste as Compared to Colgate Cavity Protection Toothpaste in Controlling Plaque and GingivitisNCT06430060Loe-Silness Gingival Index score | Phase 3 | Completed | Drug: zinc containing toothpaste, MFP Fluoride toothpaste | Plaque, Dental, Gingivitis | 86 | 2024-04-15 | 2024-08-25actual | — | 2026-03-19 |
| CL | Colgate Palmolive | $72.9B | Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.NCT06565897Plaque assessment | Phase 2 | Completed | Drug: Test regimen, Control regimen | Plaque, Dental, Gingivitis | 84 | 2024-07-26 | 2024-09-10actual | — | 2026-03-18 |
| HLN | HALEON | — | A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque AccumulationNCT06660069results2026-03-18Overall Number of Bleeding Sites (NBS) at Week 12 (Toothpaste/Mouthwash Versus [vs.] Negative Control Toothpaste) | Not applicable | Completed | Drug: Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste), CPC Mouthwash (Parodontax Active Gum Health Mouthwash), Regular Fluoride Toothpaste (Crest Cavity Protection), Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste) | Dental Plaque, Gingivitis | 199 | 2024-11-18 | 2025-03-11actual | — | 2026-03-18 |
| CL | Colgate Palmolive | $72.9B | Clinical Investigation of PerioGard (Test) RegimenNCT07210138Measurement of Loe-Silness Gingival Index score | Phase 3 | Completed | Drug: PeriGuard regimen, Colgate Dental Cream regimen | Gingivitis | 80 | 2025-08-18 | 2025-12-30actual | — | 2026-03-18 |
| HLN | HALEON | — | A Study to Evaluate the Effect of a Test (Sodium Bicarbonate) Toothpaste on the Oral MicrobiomeNCT07273539Change From Baseline in Bacterial Composition at Week 12 by Treatment Groups | Not applicable | Completed | Drug: Sodium Bicarbonate Toothpaste, Sodium Fluoride Toothpaste | Gingivitis | 74 | 2025-10-27 | 2026-02-27actual | — | 2026-03-11 |
| CL | Colgate Palmolive | $72.9B | 6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum HealthNCT07414173Improvement of gum health as measured by the Gingival Index (Löe 1967) between the study groups. | Phase 4 | Recruiting | Other: Test Mouthrinse, Control Mouthrinse | Gingivitis, Dental Plaque Accumulation | 90 | 2026-01-28 | Sep 2026 | ≤ 41 d | 2026-02-17 |
| CL | Colgate Palmolive | $72.9B | Clinical Research Study to Assess the Efficacy of Two Brushing RegimensNCT06240481Quigley and Hein Plaque Index | Phase 3 | Completed | Drug: Test Regimen, Control Regimen | Dental Plaque, Gingivitis | 90 | 2024-09-23 | 2024-12-21actual | — | 2026-02-06 |
| HLN | HALEON | — | A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival HealthNCT06602466results2026-01-22Adjusted Mean Bleeding Index (BI) at Week 4 | Not applicable | Completed | Drug: Test toothpaste, Colgate Cavity Protection Toothpaste | Dental Plaque, Gingivitis | 175 | 2024-09-23 | 2024-12-13actual | — | 2026-01-22 |
| HLN | HALEON | — | A Clinical Study Investigating the Efficacy of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival HealthNCT07169188Mean Bleeding Index (BI) at Week 12 | Not applicable | Completed | Drug: Test Fluoride Toothpaste, Colgate Cavity Protection Toothpaste | Dental Plaque, Gingivitis | 154 | 2025-09-09 | 2025-12-23actual | — | 2026-01-21 |
| CL | Colgate Palmolive | $72.9B | Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product UseNCT06770114Mombelli Modified Gingival Index | Phase 3 | Completed | Drug: Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash, PhosFlur Mouthwash | Gingivitis | 80 | 2021-10-18 | 2022-05-09actual | — | 2025-12-01 |
| CL | Colgate Palmolive | $72.9B | Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and GingivitisNCT07029438Interproximal mean Modified Gingival Index (MGI) | Phase 4 | Completed | Drug: Mouthwash, Toothpaste · Device: Floss, Toothbrush | Dental Plaque, Gingivitis | 228 | 2025-07-07 | 2025-10-16actual | — | 2025-10-30 |
| PG | Procter and Gamble | $333.4B | A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment MethodsNCT07211061Bleeding (GBI) | Phase 4 | Completed | Drug: Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, Cetylpyridinium Chloride (CPC) · Device: electric toothbrush, manual toothbrush | Gingivitis | 69 | 2011-09-21 | 2011-11-10actual | — | 2025-10-07 |
| PG | Procter and Gamble | $333.4B | Assessing Gingivitis and Plaque From a Marketed ToothpasteNCT07158112Number of Bleeding Sites | Phase 4 | Active, not recruiting | Drug: Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice, Sodium monofluorophosphate dentifrice | Gingivitis | 120 | 2025-08-30 | 2025-12-07 | — | 2025-09-23 |
| HLN | HALEON | — | A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque AccumulationNCT06933368Number of Bleeding Sites (Overall) At Week 12 | Not applicable | Completed | Drug: Crest Cavity Protection Toothpaste, Experimental Mouthwash | Dental Plaque, Gingivitis | 136 | 2025-04-21 | 2025-08-14actual | — | 2025-09-17 |
| CL | Colgate Palmolive | $72.9B | Clinical Investigation of Bleeding Reduction Efficacy on Toothpaste Containing 1.05% ChitosanNCT06955871Gingival Bleeding | Not applicable | Completed | Other: Toothpaste containing 1.05% Chitosan, Silica-based NaF Toothpaste, Toothpaste with 67% bicarbonate | Bleeding Gum, Gingivitis | 134 | 2025-04-29 | 2025-06-04actual | — | 2025-08-15 |
| CL | Colgate Palmolive | $72.9B | Evaluation of the Effect of a Toothpaste Containing 0.3% Chlorhexidine in Subjects With Established Dental Plaque and GingivitisNCT06732466Löe-Silness Gingival Index | Phase 3 | Completed | Drug: Chlorhexidine toothpaste, Placebo toothpaste without chlorhexidine and AmCl · Device: Toothbrush | Gingivitis, Gingivitis and Periodontal Diseases, Gingival Disease, Dental Plaque | 80 | 2025-03-24 | 2025-04-15actual | — | 2025-08-06 |
| PG | Procter and Gamble | $333.4B | Evaluating Gingivitis and Systemic BiomarkersNCT06962956Number Bleeding Sites | Phase 1 | Active, not recruiting | Drug: 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice, 0.454% Stannous Fluoride Dentifrice | Gingivitis | 135 | 2025-04-30 | 2025-10-31 | — | 2025-06-03 |
| CL | Colgate Palmolive | $72.9B | Anti-gingivitis MouthrinseNCT06048627Whole-mouth Mean Modified Gingival Index (MGI) | Phase 3 | Completed | Drug: Amine/zinc lactate/fluoride system, negative control | Gingivitis | 90 | 2024-03-06 | 2024-10-01actual | — | 2025-05-21 |
| CL | Colgate Palmolive | $72.9B | Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brushing, and an Alcohol-based Mouthwash Regimen With Essential Oils in Reducing Plaque and Gingivitis.NCT06598072Modified Gingival Index | Phase 3 | Completed | Drug: Mouthwash CPC+Zn+F, Essential oils mouthwash · Device: Dental floss | Gingival Bleeding, Plaque Induced Gingival Disease, Gingival Diseases, Gingivitis and Periodontal Diseases | 120 | 2024-09-17 | 2024-12-16actual | — | 2025-04-14 |
| CL | Colgate Palmolive | $72.9B | Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis ReductionNCT06607263Modified Gingival Index | Phase 3 | Completed | Drug: Mouthwash CPC+Zn+F, Essential oils mouthrinse, Toothpaste · Device: Dental floss, Toothbrush | Gingival Bleeding, Plaque Induced Gingival Disease, Gingivitis and Periodontal Diseases | 120 | 2024-09-16 | 2024-12-09actual | — | 2025-04-14 |
| HLN | HALEON | — | A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 WeeksNCT06143670results2025-03-21Adjusted Mean Change From Baseline in the Number of Bleeding Sites (NBS) at Week 12 | Not applicable | Completed | Drug: Stannous fluoride toothpaste, Sodium fluoride toothpaste | Gingivitis | 159 | 2023-11-29 | 2024-03-12actual | — | 2025-03-21 |
| HLN | HALEON | — | A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque RemovalNCT05654662results2025-01-13Adjusted Mean Change From Baseline in Number of Bleeding Sites at Week 12 | Not applicable | Completed | Drug: Corsodyl Original Dentifrice, Colgate Cavity Protection Dentifrice | Gingivitis, Dental Plaque | 197 | 2023-02-20 | 2023-11-30actual | — | 2025-01-13 |
| CL | Colgate Palmolive | $72.9B | Clinical Efficacy of the Combined Effect of Oral Irrigator and Chemicals (0.075% CPC)NCT06607172Löe-Silness Gingival Index | Phase 3 | Completed | Device: oral irrigator, oral irrigator · Drug: Cetylpyridinium Chloride (CPC) | Dental Plaque, Dental Plaque Induced Gingivitis, Dental Plaque and Gingivitis, Gingivitis | 30 | 2024-09-30 | 2024-10-22actual | — | 2024-12-13 |
| CL | Colgate Palmolive | $72.9B | Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste.NCT06563518Gingivitis Assessment | Phase 2 | Completed | Drug: Meridol, Colgate Cavity Protection | Gingivitis, Plaque | 92 | 2022-01-18 | 2022-07-10actual | — | 2024-08-21 |
| CL | Colgate Palmolive | $72.9B | Gingivitis Reduction After Use of 0.45% Stannous Fluoride ToothpasteNCT06300866Whole-Mouth Gingivitis Measurement | Phase 3 | Completed | Drug: Test, Control | Gingivitis, Plaque, Dental | 80 | 2020-08-18 | 2021-03-08actual | — | 2024-03-08 |
| PG | Procter and Gamble | $333.4B | A Clinical Study to Assess the Gingivitis and Plaque Effects of Various DentifricesNCT06140784Löe-Silness Gingivitis Evaluation | Not applicable | Completed | Drug: 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice, 0.454% Stannous Fluoride Dentifrice, 0.454% Stannous Fluoride Dentifrice | Gingivitis | 116 | 2023-09-02 | 2023-12-10actual | — | 2024-03-01 |
| PG | Procter and Gamble | $333.4B | A Clinical Study to Assess the Gingivitis Effects of Various DentifricesNCT06140771Löe-Silness Gingivitis Evaluation | Not applicable | Completed | Drug: 0.76% Sodium Monofluorophosphate Dentifrice, 1.15% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice, 0.454% Stannous Fluoride Dentifrice | Gingivitis | 115 | 2021-10-20 | 2022-02-06actual | — | 2023-11-20 |
| HLN | HALEON | — | A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture WearersNCT04290624results2023-11-18Mean Bleeding Index (BI) at Week 12 | Phase 4 | Completed | Other: Experimental Dentifrice: Stannous Fluoride, Mouth rinse: Sodium Fluoride · Device: COREGA Denture Foaming Cleanser | Gingivitis | 58 | 2020-10-14 | 2022-02-24actual | — | 2023-11-18 |
| PG | Procter and Gamble | $333.4B | A Bleeding-Model Clinical StudyNCT05916508Löe-Silness Gingivitis Evaluation | Not applicable | Completed | Drug: 0.454% stannous fluoride, 0.76% sodium monofluorophosphate, 0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM | Gingivitis | 90 | 2020-10-19 | 2020-11-20actual | — | 2023-06-23 |
| PG | Procter and Gamble | $333.4B | A Three Month Bleeding-Model Clinical StudyNCT05916521Löe-Silness Gingivitis Evaluation | Not applicable | Completed | Drug: 0.454% stannous fluoride, 0.76% sodium monofluorophosphate, 0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM | Gingivitis | 90 | 2021-11-15 | 2022-02-11actual | — | 2023-06-23 |
| PG | Procter and Gamble | $333.4B | A Clinical Study to Assess the Plaque and Gingivitis Effects of a Stannous Fluoride DentifriceNCT03936569Löe-Silness Gingivitis Evaluation | Phase 4 | Completed | Drug: Marketed Toothpaste, Marketed Cavity Protection Toothpaste | Gingivitis | 90 | 2018-10-29 | 2019-01-25actual | — | 2023-06-08 |
| PG | Procter and Gamble | $333.4B | Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)NCT01549587results2020-10-19Change From Baseline in Löe-Silness Gingivitis Index | Not applicable | Completed | Drug: 0.243% sodium fluoride, 0.454% stannous fluoride, 0.07% Cetylpyridinium chloride · Device: toothbrush, dental floss, toothbrush, dental floss | Gingivitis, Pregnancy | 746 | Feb 2012 | Feb 2014actual | — | 2023-04-21 |
| CL | Colgate Palmolive | $72.9B | Clinical Study to Assess Therapeutic Delay and Resolution of Induced GingivitisNCT05731778Bleeding Index (BOP) and Oral Inflammatory Load | Phase 4 | Completed | Drug: Stannous Fluoride Toothpaste, Colgate fluoride toothpaste | Gingivitis | 26 | 2018-12-22 | 2020-12-22actual | — | 2023-02-16 |
| PG | Procter and Gamble | $333.4B | A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival HealthNCT05594004observationalNumber of Bleeding Sites | — | Completed | Device: Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush | Gingivitis, Dental Plaque | 2,929 | 2022-04-01 | 2022-07-29actual | — | 2022-10-26 |
| CL | Colgate Palmolive | $72.9B | Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride ToothpasteNCT04033575Gingivitis Scores | Phase 4 | Completed | Drug: Colgate Total SF, Colgate Cavity Protection toothpaste | Gingivitis | 88 | 2019-03-06 | 2019-06-06actual | — | 2022-09-27 |
| PG | Procter and Gamble | $333.4B | Measuring Efficacy of an Oral-Irrigator After Three Weeks of UseNCT04899440results2022-08-01MGI-Modified Gingival Index | — | Completed | Device: Water Flosser · Other: Control | Gingivitis, Plaque | 30 | 2021-06-03 | 2021-06-24actual | — | 2022-08-01 |
| PG | Procter and Gamble | $333.4B | Stannous Fluoride and GingivitisNCT05326373MGI | Not applicable | Completed | Drug: Stannous fluoride | Gingivitis | 40 | 2022-04-11 | 2022-06-13actual | — | 2022-06-16 |
| NSIS-B.CO | Novozymes A/S | $30.2B | Effect of an Enzyme-containing Lozenge on Dental Biofilm in Healthy Individuals.NCT05070507Accumulation of dental plaque after 24 hours | Not applicable | Completed | Dietary supplement: Enzyme containing lozenge, Placebo lozenge | Dental Plaque, Gingivitis, Microbial Colonization | 24 | 2021-01-08 | 2021-02-26actual | — | 2021-10-07 |
| CL | Colgate Palmolive | $72.9B | Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected ToothbrushNCT04221334change in mean dental plaque | Not applicable | Completed | Device: Electric Toothbrush · Other: oral health care application | Gingivitis, Plaque, Dental | 79 | 2019-04-30 | 2019-07-03actual | — | 2020-01-09 |
| PG | Procter and Gamble | $333.4B | A Clinical Study to Assess the Effects of a Stannous Fluoride Dentifrice on Plaque and GingivitisNCT03936556Löe-Silness Gingivitis Evaluation | Phase 4 | Completed | Drug: Marketed toothpaste, Marketed Cavity Protection Toothpaste | Gingivitis | 84 | 2018-02-25 | 2018-06-03actual | — | 2019-12-04 |
| PG | Procter and Gamble | $333.4B | The Effects of Oscillating-Rotating Electric Toothbrushes on Plaque and Gingival HealthNCT04017507observationalNumber of Bleeding Sites | — | Completed | Device: Oscillating-rotating electric toothbrush, Side-to-side electric toothbrush, Manual toothbrush | Gingivitis, Plaque | 2,145 | 2018-01-08 | 2018-11-30actual | — | 2019-08-15 |
| PG | Procter and Gamble | $333.4B | Meta-analysis of Stannous Fluoride and the Effects on Gingival HealthNCT03970759observationalNumber of Bleeding Sites | — | Completed | Drug: Stannous Fluoride Dentifrice, Positive control dentifrice, Negative control dentifrice | Gingivitis | 2,890 | 2018-01-08 | 2018-11-30actual | — | 2019-06-17 |
| CL | Colgate Palmolive | $72.9B | Six Month Plaque and Gingivitis Study Using Colgate Total ToothpasteNCT02080273results2019-05-20Dental Plaque Score | Phase 4 | Completed | Drug: Colgate Cavity Protection toothpaste, Colgate Total toothpaste, Parodontax toothpaste | Dental Plaque, Gingivitis | 135 | Mar 2013 | Nov 2013actual | — | 2019-05-20 |
| CL | Colgate Palmolive | $72.9B | The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and GingivitisNCT02243046results2016-05-04Gingivitis Scores | Phase 2 | Completed | Drug: Control toothpaste, Experimental toothpaste, Active Comparator | Dental Plaque and Gingivitis | 162 | Dec 2014 | May 2015actual | — | 2019-02-25 |
| CL | Colgate Palmolive | $72.9B | The Clinical Investigation of a New Toothpaste Containing Stannous Fluoride as Compared to a Commercially Available Fluoride Toothpaste in Reducing Plaque and GingivitisNCT03852056Dental Plaque Scores | Phase 3 | Completed | Drug: MFP Fluoride toothpaste, Stannous fluoride toothpaste | Dental Plaque, Gingivitis | 98 | 2017-05-25 | 2017-12-07actual | — | 2019-02-22 |
| PG | Procter and Gamble | $333.4B | A Clinical Comparison of an Experimental Power Brush Compared to a Manual ToothbrushNCT03624647Modified Gingival Index | Not applicable | Completed | Device: Power toothbrush, Manual toothbrush | Gingivitis, Dental Plaque | 110 | 2018-07-09 | 2018-09-14actual | — | 2018-09-27 |
| PG | Procter and Gamble | $333.4B | A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular DentifriceNCT02543060plaque scores | Not applicable | Completed | Drug: stannous fluoride toothpaste, cavity protection toothpaste | Plaque, Gingivitis | 60 | Jun 2015 | Aug 2015actual | — | 2017-10-06 |
| PG | Procter and Gamble | $333.4B | A Pilot Study to Evaluate a Molecular Method for PlaqueNCT02574221plaque scores | Not applicable | Completed | Drug: stannous fluoride toothpaste, cavity protection toothpaste | Plaque, Gingivitis | 60 | Aug 2015 | Oct 2015actual | — | 2017-10-06 |
| PG | Procter and Gamble | $333.4B | A Follow-Up Survey of Oral Hygiene and Health Outcomes for Women Previously Enrolled in "OHMOM"NCT02922010observationalLöe-Silness Gingivitis Index | — | Completed | — | Gingivitis | 35 | Jun 2016 | 2017-06-30actual | — | 2017-09-19 |
| CL | Colgate Palmolive | $72.9B | The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the USNCT02360995results2016-03-30Dental Plaque Scores | Phase 4 | Completed | Drug: Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride toothpaste, Fluoride Mouthwash, cetylpyridinium chloride Mouthwash | Dental Plaque, Gingivitis | 129 | Jun 2014 | Aug 2014actual | — | 2016-03-30 |
| CL | Colgate Palmolive | $72.9B | Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)NCT02366689results2016-03-30Dental Plaque Scores | Phase 4 | Completed | Drug: Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste, Cetylpyridinium chloride mouthwash, Fluoride only mouthwash | Dental Plaque, Gingivitis | 179 | Jun 2014 | Dec 2014actual | — | 2016-03-30 |
| CL | Colgate Palmolive | $72.9B | Compare Anti-inflammatory DentifricesNCT00762528results2012-04-03Gingival Index (GI) | Phase 4 | Completed | Drug: Triclosan/Copolymer/fluoride toothpaste, Sodium monofluorophosphate toothpaste | Gingivitis | 49 | Feb 2009 | Feb 2010actual | — | 2015-09-10 |
| CL | Colgate Palmolive | $72.9B | Evaluate Inflammation Caused by Gingivitis in AdultsNCT00941668results2009-07-17Level of Gingival Crevicular Fluid Interleukin - 1 (GCF IL-1) at 2 Hours | Phase 4 | Completed | Drug: Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste | Gingivitis | 49 | Jan 2007 | Aug 2008actual | — | 2015-08-27 |
| CL | Colgate Palmolive | $72.9B | The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and GingivitisNCT02193165results2015-02-06Dental Plaque Scores | Phase 3 | Completed | Drug: triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash, stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash, fluoride toothpaste + fluoride Mouthwash | Dental Plaque, Gingivitis | 120 | Jul 2014 | Aug 2014actual | — | 2015-08-17 |
| CL | Colgate Palmolive | $72.9B | Comparative Efficacy of a Toothpaste That Reduces Plaque and GingivitisNCT00926328results2009-06-23Gingivitis Index | Phase 3 | Completed | Drug: Triclosan, fluoride, Fluoride | Gingivitis | 120 | Jun 2007 | Dec 2007actual | — | 2013-08-15 |
| PG | Procter and Gamble | $333.4B | A Controlled Clinical Study to Determine the Gingivitis Benefit of FlossingNCT00855933results2013-02-08Whole Mouth Lobene Modified Gingival Index Between the Brushing Only Group and the Brushing + Flossing Group [30 Days] Units on the MGI Scale | Phase 4 | Completed | Device: Experimental Floss | Gingivitis | 60 | Jan 2009 | Feb 2009actual | — | 2013-02-08 |
| PG | Procter and Gamble | $333.4B | A Controlled Clinical Study to Determine the Gingivitis Benefit of FlossingNCT00964860results2012-10-31Mean Interproximal Lobene Modified Gingival Index Between the Brushing Only Group and the Brushing + Flossing Group | Phase 3 | Completed | Device: Glide dental floss | Gingivitis | 60 | Aug 2009 | Aug 2009actual | — | 2012-10-31 |
Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.
How Gingivitis is matched — 3 exact registry spellings
A study is on this page when its ClinicalTrials.gov record names one of these conditions exactly (letter case aside). Nothing is matched by substring or stem, so a longer condition that merely contains one of these words is a different page. The list was curated by hand and last measured 2026-08-19; a spelling filed by only one study was not curated, so the counts here are a floor rather than the registry's own total for the disease.
- Gingivitis
- Gingivitis and Periodontal Diseases
- Dental Plaque and Gingivitis
Permalink · All conditions · Catalyst calendar · Every registered study · Search the whole pipeline for “Gingivitis” (a text search, wider than this page)