AGIO — blockholders· AGIOS PHARMACEUTICALS, INC.
Everyone who has reported crossing 5% of this issuer inside the capture window — Schedule 13D (active intent, with its Item-4 purpose) and Schedule 13G (passive by rule) kept apart — each with its full amendment chain and, in the fold, the cover page's sole and shared voting and dispositive power per reporting person. Percents are each group's own as-filed figures and do not add up across filers: two filers can report the same shares.
Filed passively under Rule 13d-1(b) (qualified institution), (c) (passive investor) or (d) (exempt). A 13G filer is not an activist and files no purpose statement.
| Filer | Form | % of class | Change | Shares | Filed | Chain | Control | Filing |
|---|---|---|---|---|---|---|---|---|
| Farallon Capital Management, L.L.C. | 13G/A No. 5QII | 9.9% | first captured | 5,917,400 | 2026-08-03 | 1 | SEC ↗ | |
| Farallon Capital Partners, L.P. | 13G/A No. 4Passive | 8.8% | ▼ -1.1pp | 5,159,505 | 2026-02-09 | 2 | SEC ↗ | |
| BlackRock, Inc. | 13G/A No. 7QII | 7.8% | first captured | 4,513,170 | 2025-07-17 | 1 | SEC ↗ | |
| STATE STREET CORPORATION | 13GQII | 5.3% | NEW | 3,108,145 | 2026-02-09 | 1 | SEC ↗ | |
| Vanguard Capital Management | 13GQII | 5.27% | NEW | 3,088,169 | 2026-04-29 | 1 | SEC ↗ | |
| Lynx1 Capital Management LP | 13GPassive | 5.1% | NEW | 3,013,949 | 2026-05-06 | 1 | SEC ↗ | |
| D. E. Shaw & Co., L.P. | 13GPassive | 5.1% | NEW | 3,034,031 | 2026-07-02 | 1 | SEC ↗ | |
| Paradigm BioCapital Advisors LP | 13G/A No. 1Passive | 4.9% | ▼ -0.3pp | 2,873,555 | 2025-11-14 | 2 | SEC ↗ | |
| Armistice Capital, LLC | 13G/A No. 1QII | 4.57% | ▼ -0.64pp | 2,716,000 | 2026-05-15 | 2 | SEC ↗ | |
| The Vanguard Group | 13G/A No. 10QII | 0% | first captured | 0 | 2026-03-26 | 1 | SEC ↗ |
Source: SEC EDGAR Schedule 13D/G structured XML (public domain) · newest filing 2026-08-03 · capture 2024-01-10 → 2026-08-21 reported positions only — not a portfolio
Voting is not disposition. Each reporting person's cover page splits its holding into VOTING power (sole / shared) and DISPOSITIVE power (sole / shared). Voting and dispositive totals are summed WITHIN a person only — never across persons, because a group's members report overlapping interests in the same shares and the filing's aggregate is not their sum. Where a person's voting total is below its reported aggregate, the difference is shares it reports beneficial ownership of with no voting power reported; it is shown as a gap, never as a second position.
Percent is as filed. Percent is the filing's own percent of class, as filed (0–100). It's the reporting group's figure — not summed across filers, not recomputed against shares outstanding, not rescaled. Share counts are as filed and never subtracted across filings (a split would make that meaningless); the only change we show is the change in the as-filed percent against the prior captured filing.
We never call an amendment “new”. A filing is 'first captured' when we hold nothing earlier for that company + filer. On an amendment that means the original predates our window, not that the position is new — so we never badge an amendment 'new,' even when the raw data says so.
Escalations. An escalation is a filer moving from a passive 13G to an active 13D on the same company — telling the SEC it may now seek to influence control. It's a lower bound: a 13G filed before our window began is invisible and never guessed. If the 13D leg is a 13D/A, an earlier 13D predates our window, so the crossing shown is the first one visible inside it, not necessarily the filer's first.
Parsed Schedule 13D/G XML (events.db schedule_13dg + schedule_13dg_persons). 13D = active intent; 13G filers report passively under Rule 13d-1(b) QII / (c) Passive / (d) Exempt and are never activists. Percents are the reporting group's own as-filed figures and are NOT additive across filers — two filers can report the same shares. Structured 13D/13G coverage starts December 2024 (SEC XML mandate).