Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-18 | Casdin Eli | Director,TenPercentOwner | +Exercise | 3,576 | — | — |
| 2026-06-18 | Leproust Emily M. | Director | +Exercise | 3,576 | — | — |
| 2026-06-18 | Meister Keith A. | Director,TenPercentOwner | +Exercise | 3,576 | — | — |
| 2026-06-18 | PFENNIGER RICHARD C JR | Director | +Exercise | 3,576 | — | — |
| 2026-06-18 | RUCH JOSHUA | Director | +Exercise | 3,576 | — | — |
| 2026-06-18 | Ryan Jason | Director | +Exercise | 3,576 | — | — |
| 2026-06-16 | Stueland Katherine | Director,Officer | −Sell | 2,429 | $61.50 | $149,384 |
| 2026-06-16 | Stueland Katherine | Director,Officer | +Exercise | 18,750 | — | — |
| 2026-06-16 | Stueland Katherine | Director,Officer | −Sell | 2,140 | $59.75 | $127,865 |
| 2026-06-16 | Stueland Katherine | Director,Officer | −Sell | 5,932 | $60.83 | $360,844 |
| 2026-06-16 | Feeley Kevin | Officer | −Sell | 760 | $59.75 | $45,410 |
| 2026-06-16 | Feeley Kevin | Officer | +Exercise | 7,197 | — | — |
| 2026-06-16 | Feeley Kevin | Officer | −Sell | 863 | $61.50 | $53,075 |
| 2026-06-16 | Feeley Kevin | Officer | −Sell | 2,106 | $60.83 | $128,108 |
| 2026-06-09 | Stueland Katherine | Director,Officer | +Exercise | 6,546 | — | — |
| 2026-06-09 | Stueland Katherine | Director,Officer | −Sell | 3,639 | $53.77 | $195,669 |
| 2026-06-09 | Feeley Kevin | Officer | −Sell | 1,266 | $53.77 | $68,073 |
| 2026-06-09 | Feeley Kevin | Officer | +Exercise | 2,462 | — | — |
| 2026-06-05 | Casdin Eli | Director,TenPercentOwner | +Buy | 50,000 | $52.86 | $3M |
| 2026-06-04 | Casdin Eli | Director,TenPercentOwner | +Buy | 150,000 | $56.44 | $8M |
| 2026-06-01 | Feeley Kevin | Officer | −Sell | 369 | $51.74 | $19,092 |
| 2026-06-01 | Feeley Kevin | Officer | +Exercise | 717 | — | — |
| 2026-05-20 | Casdin Partners Master Fund, L.P. | Director,TenPercentOwner | +Buy | 140,000 | $43.81 | $6M |
| 2026-05-19 | Casdin Partners Master Fund, L.P. | Director,TenPercentOwner | +Buy | 185,000 | $42.60 | $8M |
| 2026-05-18 | Casdin Partners Master Fund, L.P. | Director,TenPercentOwner | +Buy | 175,000 | $42.55 | $7M |
| 2026-05-15 | Meister Keith A. | Director,TenPercentOwner | +Buy | 27,408 | $38.28 | $1M |
| 2026-05-15 | Meister Keith A. | Director,TenPercentOwner | +Buy | 18,865 | $39.83 | $751,393 |
| 2026-05-14 | Meister Keith A. | Director,TenPercentOwner | +Buy | 88,107 | $39.08 | $3M |
| 2026-05-14 | Meister Keith A. | Director,TenPercentOwner | +Buy | 51,893 | $39.92 | $2M |
| 2026-05-13 | Meister Keith A. | Director,TenPercentOwner | +Buy | 94,074 | $38.82 | $4M |
| 2026-05-13 | Meister Keith A. | Director,TenPercentOwner | +Buy | 70,926 | $39.45 | $3M |
| 2026-05-11 | Meister Keith A. | Director,TenPercentOwner | +Buy | 252,734 | $39.65 | $10M |
| 2026-05-11 | Meister Keith A. | Director,TenPercentOwner | +Buy | 532 | $40.35 | $21,466 |
| 2026-05-11 | Meister Keith A. | Director,TenPercentOwner | +Buy | 246,734 | $38.91 | $10M |
| 2026-05-08 | Meister Keith A. | Director,TenPercentOwner | +Buy | 73,104 | $41.15 | $3M |
| 2026-05-08 | Meister Keith A. | Director,TenPercentOwner | +Buy | 79,144 | $40.67 | $3M |
| 2026-05-08 | Meister Keith A. | Director,TenPercentOwner | +Buy | 3,396 | $38.70 | $131,425 |
| 2026-05-08 | Meister Keith A. | Director,TenPercentOwner | +Buy | 15,745 | $38.00 | $598,310 |
| 2026-05-07 | Meister Keith A. | Director,TenPercentOwner | +Buy | 116,412 | $38.46 | $4M |
| 2026-05-07 | Meister Keith A. | Director,TenPercentOwner | +Buy | 123,393 | $37.60 | $5M |
| 2026-05-07 | Meister Keith A. | Director,TenPercentOwner | +Buy | 14,786 | $36.33 | $537,175 |
| 2026-05-07 | Meister Keith A. | Director,TenPercentOwner | +Buy | 128,181 | $35.46 | $5M |
| 2026-05-07 | Meister Keith A. | Director,TenPercentOwner | +Buy | 94,356 | $39.39 | $4M |
| 2026-05-07 | Meister Keith A. | Director,TenPercentOwner | +Buy | 56,630 | $40.46 | $2M |
| 2026-04-29 | Feeley Kevin | Officer | −Sell | 392 | $65.19 | $25,554 |
| 2026-04-29 | Feeley Kevin | Officer | +Exercise | 754 | — | — |
| 2026-04-29 | Stueland Katherine | Director,Officer | +Exercise | 3,874 | — | — |
| 2026-04-29 | Stueland Katherine | Director,Officer | −Sell | 18 | $64.12 | $1,154 |
| 2026-04-29 | Stueland Katherine | Director,Officer | −Sell | 2,154 | $65.20 | $140,441 |
| 2026-03-26 | Stueland Katherine | Director,Officer | −Sell | 5,292 | $64.60 | $341,863 |
| 2026-03-26 | Stueland Katherine | Director,Officer | −Sell | 13,412 | $63.28 | $848,711 |
| 2026-03-26 | Stueland Katherine | Director,Officer | −Sell | 9,883 | $65.21 | $644,470 |
| 2026-03-26 | Stueland Katherine | Director,Officer | +Exercise | 80,000 | — | — |
| 2026-03-26 | Stueland Katherine | Director,Officer | −Sell | 13,229 | $61.29 | $810,805 |
| 2026-03-26 | Stueland Katherine | Director,Officer | −Sell | 5,117 | $62.33 | $318,943 |
| 2026-03-26 | Feeley Kevin | Officer | +Exercise | 16,250 | — | — |
| 2026-03-26 | Feeley Kevin | Officer | −Sell | 2,485 | $61.29 | $152,306 |
| 2026-03-26 | Feeley Kevin | Officer | −Sell | 961 | $62.33 | $59,899 |
| 2026-03-26 | Feeley Kevin | Officer | −Sell | 2,520 | $63.28 | $159,466 |
| 2026-03-26 | Feeley Kevin | Officer | −Sell | 995 | $64.60 | $64,277 |
| 2026-03-26 | Feeley Kevin | Officer | −Sell | 1,857 | $65.21 | $121,095 |
| 2026-03-16 | Feeley Kevin | Officer | −Sell | 2,384 | $76.35 | $182,018 |
| 2026-03-16 | Feeley Kevin | Officer | −Sell | 3,065 | $77.05 | $236,158 |
| 2026-03-16 | Feeley Kevin | Officer | −Sell | 257 | $77.94 | $20,031 |
| 2026-03-16 | Feeley Kevin | Officer | +Exercise | 7,197 | — | — |
| 2026-03-16 | Stueland Katherine | Director,Officer | −Sell | 7,178 | $76.35 | $548,040 |
| 2026-03-16 | Stueland Katherine | Director,Officer | −Sell | 9,229 | $77.05 | $711,094 |
| 2026-03-16 | Stueland Katherine | Director,Officer | −Sell | 772 | $77.94 | $60,170 |
| 2026-03-16 | Stueland Katherine | Director,Officer | +Exercise | 18,750 | — | — |
| 2026-03-15 | Feeley Kevin | Officer | +Exercise | 3,815 | — | — |
| 2026-03-15 | Stueland Katherine | Director,Officer | +Exercise | 11,921 | — | — |
| 2026-03-09 | Stueland Katherine | Director,Officer | −Sell | 3,678 | $86.75 | $319,067 |
| 2026-03-09 | Stueland Katherine | Director,Officer | +Exercise | 6,546 | — | — |
| 2026-03-09 | Feeley Kevin | Officer | +Exercise | 2,462 | — | — |
| 2026-03-09 | Feeley Kevin | Officer | −Sell | 1,280 | $86.75 | $111,040 |
| 2026-03-06 | Stueland Katherine | Director,Officer | +Grant | 3,404 | $88.11 | $299,926 |
| 2026-03-06 | Feeley Kevin | Officer | +Grant | 1,986 | $88.11 | $174,986 |
| 2026-03-05 | Meister Keith A. | Director,TenPercentOwner | +Buy | 60,892 | $81.37 | $5M |
| 2026-03-05 | Meister Keith A. | Director,TenPercentOwner | +Buy | 47,623 | $80.55 | $4M |
| 2026-03-05 | Meister Keith A. | Director,TenPercentOwner | +Buy | 1,971 | $78.91 | $155,532 |
| 2026-03-05 | Meister Keith A. | Director,TenPercentOwner | +Buy | 304 | $77.96 | $23,700 |
| 2026-03-05 | Meister Keith A. | Director,TenPercentOwner | +Buy | 29,236 | $82.06 | $2M |
| 2026-03-04 | Stueland Katherine | Director,Officer | −Sell | 9,133 | $79.25 | $723,790 |
| 2026-03-04 | Stueland Katherine | Director,Officer | −Sell | 10,465 | $78.61 | $822,654 |
| 2026-03-04 | Stueland Katherine | Director,Officer | −Sell | 5,861 | $77.63 | $454,989 |
| 2026-03-04 | Feeley Kevin | Officer | −Sell | 1,424 | $77.63 | $110,545 |
| 2026-03-04 | Feeley Kevin | Officer | −Sell | 2,220 | $79.25 | $175,935 |
| 2026-03-04 | Feeley Kevin | Officer | −Sell | 2,543 | $78.61 | $199,905 |
| 2026-03-03 | Stueland Katherine | Director,Officer | +Grant | 47,684 | — | — |
| 2026-03-03 | Feeley Kevin | Officer | +Grant | 15,262 | — | — |
| 2026-03-03 | Meister Keith A. | Director,TenPercentOwner | +Buy | 249 | $75.99 | $18,922 |
| 2026-03-03 | Meister Keith A. | Director,TenPercentOwner | +Buy | 921 | $75.66 | $69,683 |
| 2026-03-03 | Meister Keith A. | Director,TenPercentOwner | +Buy | 200 | $72.00 | $14,400 |
| 2026-03-03 | Meister Keith A. | Director,TenPercentOwner | +Buy | 8,439 | $71.48 | $603,220 |
| 2026-03-03 | Meister Keith A. | Director,TenPercentOwner | +Buy | 19,686 | $70.34 | $1M |
| 2026-03-02 | Feeley Kevin | Officer | −Sell | 287 | $77.52 | $22,248 |
| 2026-03-01 | Feeley Kevin | Officer | +Exercise | 718 | — | — |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 1,034 | $84.93 | $87,818 |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 100 | $90.45 | $9,045 |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 328 | $88.66 | $29,080 |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 1,572 | $87.66 | $137,802 |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 623 | $86.35 | $53,796 |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 779 | $83.04 | $64,688 |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 1,425 | $83.83 | $119,458 |
| 2026-02-04 | Dechairo Bryan | Officer | −Sell | 100 | $91.92 | $9,192 |
| 2026-02-02 | Dechairo Bryan | Officer | −Sell | 93 | $96.77 | $9,000 |
| 2026-02-02 | Dechairo Bryan | Officer | −Sell | 1,662 | $99.40 | $165,203 |
| 2026-02-02 | Dechairo Bryan | Officer | −Sell | 492 | $98.61 | $48,516 |
| 2026-02-02 | Dechairo Bryan | Officer | −Sell | 1,166 | $100.31 | $116,961 |
| 2026-02-01 | Dechairo Bryan | Officer | +Exercise | 9,374 | — | — |
| 2026-01-29 | Stueland Katherine | Director,Officer | −Sell | 1,653 | $94.00 | $155,382 |
| 2026-01-29 | Stueland Katherine | Director,Officer | +Exercise | 3,874 | — | — |
| 2026-01-29 | Feeley Kevin | Officer | +Exercise | 754 | — | — |
| 2026-01-29 | Feeley Kevin | Officer | −Sell | 315 | $94.00 | $29,610 |
| 2026-01-29 | Feeley Kevin | Officer | −Sell | 2 | $92.06 | $184 |
| 2025-12-16 | Stueland Katherine | Director,Officer | −Sell | 274 | $149.20 | $40,881 |
| 2025-12-16 | Stueland Katherine | Director,Officer | −Sell | 1,970 | $146.93 | $289,452 |
| 2025-12-16 | Stueland Katherine | Director,Officer | −Sell | 1,628 | $145.36 | $236,646 |
| 2025-12-16 | Stueland Katherine | Director,Officer | −Sell | 940 | $144.27 | $135,614 |
| 2025-12-16 | Stueland Katherine | Director,Officer | −Sell | 74 | $150.75 | $11,156 |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
