TVTX close: $13.2 on 2023-08-21 to $64.5 on 2026-08-20.
Split-adj closes · 240 of 1,376 · price returnⓘ
At a glance
Short interest12.4% of sh out
Days to cover9.4d
13F net flow (QoQ)−2.02%
Top-10 13F concentration55.1%
Next report (est.)2026-11-03
SI 2026-07-31 · 13F 2026-Q1ⓘ
Key fundamentalsFY 2025
Sales (TTM)$591.3M
Earnings (TTM)-$43.5M
ROE−29.4%
Net margin−5.2%
ROIC−444.4%
Sales growth 3Y64.9%
FY ratios · TTM sales/earnings (USD)ⓘ
Trailing returns
YTD+68.7%
1Y+258.7%
3Y+388.3%
5Y+219.3%
Since incept. (ann.)+15.2%
Total return · from 2021-02-22ⓘ
Risk
Ann. volatility (1Y)72.1%
Ann. volatility (3Y)72.0%
Sharpe (1Y)2.17
Sharpe (3Y)1.11
Max drawdown (1Y)−33.5%
Max drawdown (3Y)−64.6%
Beta (3Y vs SPY)2.33
Daily returns, ann.ⓘ
Top institutional holders13F 2026-Q1
Manager
Shares
Value
% sh out
QoQ
JANUS HENDERSON GROUP PLC
11.4M
$339M
12.38%
+8.6%
FMR LLC
11.0M
$326M
11.89%
+14.0%
BlackRock, Inc.
7.8M
$232M
8.45%
−1.0%
STATE STREET CORP
5.0M
$147M
5.38%
+4.3%
ARMISTICE CAPITAL, LLC
4.9M
$146M
5.31%
+30.1%
PERCEPTIVE ADVISORS LLC
4.1M
$123M
4.49%
−3.2%
VANGUARD CAPITAL MANAGEMENT LLC
4.0M
$120M
4.39%
new
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.
3.3M
$97M
3.55%
−13.3%
Δ vs 2025-Q4 · Institutional 13F holdings sum to 109.9% of shares outstanding. Readings above 100% reflect securities-lending double counting: shares on loan to short sellers are reported long by both the lending institution and the one that bought them. FINRA short interest of 14,008,379 shares (settlement 2026-05-15) accounts for the excess.ⓘ
Latest reported quarterslast report 2026-08-04
Period end
Reported
EPS
EPS YoY
Revenue
Rev YoY
2026-06-30
2026-08-04
−$0.37
—
$169.6M
+48.2%
2026-03-31
2026-05-04
−$0.40
—
$127.2M
+55.6%
2025-12-31
2026-02-19
—
—
$129.7M
+73.4%
2025-09-30
2025-10-30
$0.28
—
$164.9M
+162.1%
As-reported XBRL · next 2026-11-03 est.ⓘ
Segment mixFY2025 (ended Dec 2025)
Reportable 100%
business · TAGGED revenueⓘ
Basis & disclosures
EOD closes · nothing imputed or averaged · absent “—”
As-of differs by block · 13F = US long, 45+d lag, LOWER bound
Not investment advice · no recommendation, price target or solicitation
EDGAR + foreign registers · marketstack (licensed EOD) · spzco.com/methodology
