Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-16 | Stergiou Angelos M. | Director,Officer | +Grant | 1,065,000 | — | — |
| 2026-01-07 | Wasman Jane | Director | +Grant | 50,000 | — | — |
| 2026-01-07 | Kalin Katherine Bach | Director | +Grant | 50,000 | — | — |
| 2026-01-07 | Burns John Thomas | Officer | +Grant | 300,000 | — | — |
| 2026-01-07 | CICIC DRAGAN | Officer | +Grant | 300,000 | — | — |
| 2026-01-07 | SCHEINBERG DAVID A | Director | +Grant | 50,000 | — | — |
| 2026-01-07 | VAN NOSTRAND ROBERT L | Director | +Grant | 50,000 | — | — |
| 2026-01-07 | Varian John | Director | +Grant | 50,000 | — | — |
| 2025-12-03 | Stergiou Angelos M. | Director,Officer | −Other | 187,066 | $1.50 | $280,599 |
| 2025-12-03 | Burns John Thomas | Officer | −Other | 58,592 | $1.50 | $87,888 |
| 2025-12-03 | CICIC DRAGAN | Officer | −Other | 63,800 | $1.50 | $95,700 |
| 2025-11-19 | Kalin Katherine Bach | Director | +Buy | 63,400 | $1.59 | $100,806 |
| 2025-06-12 | VAN NOSTRAND ROBERT L | Director | +Buy | 10,000 | $1.48 | $14,800 |
| 2025-05-30 | Wasman Jane | Director | +Buy | 20,000 | $1.69 | $33,800 |
| 2025-05-22 | Kalin Katherine Bach | Director | +Buy | 20,000 | $1.80 | $36,000 |
| 2025-01-10 | CICIC DRAGAN | Officer | +Grant | 113,000 | — | — |
| 2025-01-10 | CICIC DRAGAN | Officer | +Grant | 81,300 | — | — |
| 2025-01-10 | Varian John | Director | +Grant | 12,500 | — | — |
| 2025-01-10 | Kalin Katherine Bach | Director | +Grant | 12,500 | — | — |
| 2025-01-10 | VAN NOSTRAND ROBERT L | Director | +Grant | 12,500 | — | — |
| 2025-01-10 | Wasman Jane | Director | +Grant | 12,500 | — | — |
| 2025-01-10 | SCHEINBERG DAVID A | Director | +Grant | 12,500 | — | — |
| 2025-01-10 | Stergiou Angelos M. | Director,Officer | +Grant | 257,000 | — | — |
| 2025-01-10 | Stergiou Angelos M. | Director,Officer | +Grant | 243,900 | — | — |
| 2025-01-10 | Burns John Thomas | Officer | +Grant | 81,300 | — | — |
| 2025-01-10 | Burns John Thomas | Officer | +Grant | 113,000 | — | — |
| 2024-12-04 | Burns John Thomas | Officer | −Other | 7,165 | $1.13 | $8,096 |
| 2024-12-04 | Stergiou Angelos M. | Director,Officer | −Other | 28,289 | $1.13 | $31,967 |
| 2024-12-04 | CICIC DRAGAN | Officer | −Other | 8,256 | $1.13 | $9,329 |
| 2024-01-22 | Burns John Thomas | Officer | +Grant | 47,000 | — | — |
| 2024-01-22 | VAN NOSTRAND ROBERT L | Director | +Grant | 6,000 | — | — |
| 2024-01-22 | Varian John | Director | +Grant | 6,000 | — | — |
| 2024-01-22 | Francomano Robert | Officer | +Grant | 20,000 | — | — |
| 2024-01-22 | Wasman Jane | Director | +Grant | 6,000 | — | — |
| 2024-01-22 | Kalin Katherine Bach | Director | +Grant | 6,000 | — | — |
| 2024-01-22 | WOOD BARBARA A | Officer | +Grant | 35,000 | — | — |
| 2024-01-22 | SCHEINBERG DAVID A | Director | +Grant | 6,000 | — | — |
| 2024-01-22 | Stergiou Angelos M. | Director,Officer | +Grant | 159,000 | — | — |
| 2023-12-06 | Burns John Thomas | Officer | −Other | 2,929 | $1.08 | $3,163 |
| 2023-12-06 | Francomano Robert | Officer | −Other | 1,082 | $1.08 | $1,169 |
| 2023-12-06 | Stergiou Angelos M. | Director,Officer | −Other | 12,268 | $1.08 | $13,249 |
| 2023-12-06 | WOOD BARBARA A | Officer | −Other | 4,119 | $1.08 | $4,449 |
| 2023-02-02 | Kalin Katherine Bach | Director | +Grant | 2,500 | — | — |
| 2023-02-02 | SCHEINBERG DAVID A | Director | +Grant | 2,500 | — | — |
| 2023-02-02 | VAN NOSTRAND ROBERT L | Director | +Grant | 2,500 | — | — |
| 2023-02-02 | Wasman Jane | Director | +Grant | 2,500 | — | — |
| 2023-02-02 | Varian John | Director | +Grant | 2,500 | — | — |
| 2023-02-02 | Francomano Robert | Officer | +Grant | 12,000 | — | — |
| 2023-02-02 | Stergiou Angelos M. | Director,Officer | +Grant | 58,000 | — | — |
| 2023-02-02 | Burns John Thomas | Officer | +Grant | 20,000 | — | — |
| 2023-02-02 | WOOD BARBARA A | Officer | +Grant | 20,000 | — | — |
| 2022-12-05 | WOOD BARBARA A | Officer | −Sell | 2,153 | $2.59 | $5,576 |
| 2022-12-05 | Burns John Thomas | Officer | −Sell | 1,159 | $2.59 | $3,002 |
| 2022-12-05 | Stergiou Angelos M. | Director,Officer | −Sell | 6,494 | $2.61 | $16,949 |
| 2022-01-31 | Burns John Thomas | Officer | +Grant | 9,600 | — | — |
| 2022-01-31 | SCHEINBERG DAVID A | Director | +Grant | 1,900 | — | — |
| 2022-01-31 | Stergiou Angelos M. | Director,Officer | +Grant | 44,000 | — | — |
| 2022-01-31 | VAN NOSTRAND ROBERT L | Director | +Grant | 1,900 | — | — |
| 2022-01-31 | Varian John | Director | +Grant | 1,900 | — | — |
| 2022-01-31 | Wasman Jane | Director | +Grant | 1,900 | — | — |
| 2022-01-31 | WOOD BARBARA A | Officer | +Grant | 13,000 | — | — |
| 2021-12-02 | Burns John Thomas | Officer | −Sell | 231 | $6.27 | $1,448 |
| 2021-12-02 | WOOD BARBARA A | Officer | −Sell | 847 | $6.25 | $5,294 |
| 2021-12-02 | Stergiou Angelos M. | Director,Officer | −Sell | 2,120 | $6.25 | $13,250 |
| 2021-03-04 | Stergiou Angelos M. | Director,Officer | +Grant | 19,750 | — | — |
| 2021-03-04 | Burns John Thomas | Officer | +Grant | 2,875 | — | — |
| 2021-03-04 | WOOD BARBARA A | Officer | +Grant | 7,875 | — | — |
| 2020-03-12 | Burns John Thomas | Officer | +Grant | 15,000 | — | — |
| 2020-03-12 | Stergiou Angelos M. | Director,Officer | +Grant | 95,000 | — | — |
| 2020-03-12 | WOOD BARBARA A | Officer | +Grant | 35,000 | — | — |
| 2018-12-31 | Stergiou Angelos M. | Director,Officer | −Sell | 23,277 | $1.25 | $29,096 |
| 2018-09-24 | Tafur Daniel | TenPercentOwner | −Other | 325,799 | — | — |
| 2018-09-24 | Tafur Daniel | TenPercentOwner | −Other | 1,521,863 | — | — |
| 2018-09-24 | Tafur Daniel | TenPercentOwner | −Other | 676,324 | — | — |
| 2017-12-29 | EQC Private Markets SAC Fund Ltd-EQC Biotech Sely II Fund` | TenPercentOwner | +Grant | 3,343 | — | — |
| 2017-12-29 | EQC Private Markets SAC Fund Ltd-EQC Biotech Sely II Fund` | TenPercentOwner | +Grant | 3,343 | — | — |
| 2017-12-29 | EQC Private Markets SAC Fund Ltd-EQC Biotech Sely II Fund` | TenPercentOwner | +Grant | 58,208 | — | — |
| 2017-12-29 | EQC Private Markets SAC Fund Ltd-EQC Biotech Sely II Fund` | TenPercentOwner | +Grant | 149,766 | — | — |
| 2017-12-29 | EQC Private Markets SAC Fund Ltd-EQC Biotech Sely II Fund` | TenPercentOwner | +Grant | 676,324 | — | — |
| 2017-12-29 | EQC Private Markets SAC Fund Ltd-EQC Biotech Sely II Fund` | TenPercentOwner | +Grant | 1,521,863 | — | — |
| 2017-12-29 | EQC Private Markets SAC Fund Ltd-EQC Biotech Sely II Fund` | TenPercentOwner | +Grant | 325,799 | — | — |
| 2017-12-29 | SCHEINBERG DAVID A | Director | +Grant | 9,107 | — | — |
| 2017-12-29 | Stergiou Andelos M. | Director,Officer | +Grant | 450,135 | — | — |
| 2017-12-29 | SCHEINBERG DAVID A | Director | +Grant | 9,107 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.