Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,223 | — | — |
| 2026-06-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,817 | — | — |
| 2026-06-23 | DIORIO CHRIS PH.D. | Director,Officer | −Tax w/h | 1,197 | $125.22 | $149,888 |
| 2026-06-23 | Baker Cary | Officer | +Exercise | 479 | — | — |
| 2026-06-23 | Baker Cary | Officer | +Exercise | 597 | — | — |
| 2026-06-23 | Baker Cary | Officer | −Tax w/h | 424 | $125.22 | $53,093 |
| 2026-06-15 | DIORIO CHRIS PH.D. | Director,Officer | −Gift | 10,000 | — | — |
| 2026-06-09 | SYLEBRA CAPITAL LLC | Director | −Sell | 12,105 | $127.36 | $2M |
| 2026-06-09 | SYLEBRA CAPITAL LLC | Director | −Sell | 19,105 | $127.36 | $2M |
| 2026-06-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 12,528 | $125.97 | $2M |
| 2026-06-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 33,000 | $130.07 | $4M |
| 2026-06-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 33,000 | $130.07 | $4M |
| 2026-06-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 12,528 | $125.97 | $2M |
| 2026-06-05 | SYLEBRA CAPITAL LLC | Director | −Sell | 35,877 | $122.50 | $4M |
| 2026-06-05 | SYLEBRA CAPITAL LLC | Director | −Sell | 11,602 | $128.87 | $1M |
| 2026-06-04 | SYLEBRA CAPITAL LLC | Director | −Sell | 33,412 | $136.84 | $5M |
| 2026-06-03 | SYLEBRA CAPITAL LLC | Director | −Sell | 6,313 | $139.17 | $878,580 |
| 2026-06-02 | SYLEBRA CAPITAL LLC | Director | −Sell | 38,724 | $142.31 | $6M |
| 2026-06-01 | SYLEBRA CAPITAL LLC | Director | −Sell | 7,163 | $144.29 | $1M |
| 2026-05-29 | SYLEBRA CAPITAL LLC | Director | −Sell | 48,504 | $150.78 | $7M |
| 2026-05-28 | Rao Meera | Director | +Exercise | 3,114 | — | — |
| 2026-05-28 | Sanghi Steve | Director | +Exercise | 3,425 | — | — |
| 2026-05-28 | PADVAL UMESH | Director | +Exercise | 3,114 | — | — |
| 2026-05-28 | WASHINGTON MIRON | Director | +Exercise | 3,114 | — | — |
| 2026-05-28 | Gibson Daniel Patrick | Director | +Exercise | 3,114 | — | — |
| 2026-05-26 | DIORIO CHRIS PH.D. | Director,Officer | +Other | 180,000 | $156.68 | $28M |
| 2026-05-26 | DIORIO CHRIS PH.D. | Director,Officer | −Other | 180,000 | $156.68 | $28M |
| 2026-05-11 | SYLEBRA CAPITAL LLC | Director | +Sell | 24,126 | $154.46 | $4M |
| 2026-05-11 | SYLEBRA CAPITAL LLC | Director | +Sell | 12,706 | $154.46 | $2M |
| 2026-05-11 | SYLEBRA CAPITAL LLC | Director | −Sell | 24,126 | $154.46 | $4M |
| 2026-05-11 | SYLEBRA CAPITAL LLC | Director | −Sell | 12,706 | $154.46 | $2M |
| 2026-05-08 | SYLEBRA CAPITAL LLC | Director | +Sell | 9,522 | $149.97 | $1M |
| 2026-05-08 | SYLEBRA CAPITAL LLC | Director | +Sell | 1,560 | $151.32 | $236,059 |
| 2026-05-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 25,896 | $152.73 | $4M |
| 2026-05-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 9,522 | $149.97 | $1M |
| 2026-05-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 1,560 | $151.32 | $236,059 |
| 2026-05-08 | SYLEBRA CAPITAL LLC | Director | −Sell | 25,896 | $152.73 | $4M |
| 2026-05-07 | SYLEBRA CAPITAL LLC | Director | −Sell | 36,171 | $152.73 | $6M |
| 2026-05-07 | SYLEBRA CAPITAL LLC | Director | −Sell | 36,171 | $152.73 | $6M |
| 2026-03-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 2,594 | — | — |
| 2026-03-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,224 | — | — |
| 2026-03-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,817 | — | — |
| 2026-03-23 | DIORIO CHRIS PH.D. | Director,Officer | −Tax w/h | 2,218 | $101.17 | $224,395 |
| 2026-03-23 | Baker Cary | Officer | +Exercise | 597 | — | — |
| 2026-03-23 | Baker Cary | Officer | +Exercise | 782 | — | — |
| 2026-03-23 | Baker Cary | Officer | +Exercise | 479 | — | — |
| 2026-03-23 | Baker Cary | Officer | −Tax w/h | 732 | $101.17 | $74,056 |
| 2026-02-20 | DIORIO CHRIS PH.D. | Director,Officer | +Grant | 21,734 | — | — |
| 2026-02-20 | DIORIO CHRIS PH.D. | Director,Officer | −Tax w/h | 7,435 | $127.92 | $951,085 |
| 2026-02-20 | Baker Cary | Officer | −Tax w/h | 2,234 | $127.92 | $285,773 |
| 2026-02-20 | Baker Cary | Officer | +Grant | 8,508 | — | — |
| 2026-02-17 | DIORIO CHRIS PH.D. | Director,Officer | −Gift | 1,836 | — | — |
| 2025-12-23 | Baker Cary | Officer | +Exercise | 479 | — | — |
| 2025-12-23 | Baker Cary | Officer | +Exercise | 596 | — | — |
| 2025-12-23 | Baker Cary | Officer | −Tax w/h | 732 | $171.99 | $125,897 |
| 2025-12-23 | Baker Cary | Officer | +Exercise | 781 | — | — |
| 2025-12-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,224 | — | — |
| 2025-12-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,817 | — | — |
| 2025-12-23 | DIORIO CHRIS PH.D. | Director,Officer | −Tax w/h | 2,218 | $171.99 | $381,474 |
| 2025-12-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 2,594 | — | — |
| 2025-12-15 | SYLEBRA CAPITAL LLC | Other | −Sell | 134,629 | $150.36 | $20M |
| 2025-12-12 | SYLEBRA CAPITAL LLC | Other | −Sell | 50,573 | $146.62 | $7M |
| 2025-12-11 | SYLEBRA CAPITAL LLC | Other | −Sell | 95,345 | $152.87 | $15M |
| 2025-12-10 | Gibson Daniel Patrick | Director | −Sell | 84,604 | $155.49 | $13M |
| 2025-12-09 | Gibson Daniel Patrick | Director | −Sell | 40 | $160.01 | $6,400 |
| 2025-12-08 | Gibson Daniel Patrick | Director | −Sell | 2,494 | $160.72 | $400,836 |
| 2025-12-05 | Gibson Daniel Patrick | Director | −Sell | 1,373 | $161.04 | $221,108 |
| 2025-12-04 | Gibson Daniel Patrick | Director | −Sell | 3,167 | $160.59 | $508,589 |
| 2025-12-03 | Gibson Daniel Patrick | Director | −Sell | 41,221 | $167.97 | $7M |
| 2025-12-02 | SYLEBRA CAPITAL LLC | Other | −Sell | 41,874 | $168.23 | $7M |
| 2025-12-01 | SYLEBRA CAPITAL LLC | Other | −Sell | 31,058 | $167.02 | $5M |
| 2025-11-28 | SYLEBRA CAPITAL LLC | Other | −Sell | 22,297 | $172.62 | $4M |
| 2025-11-26 | SYLEBRA CAPITAL LLC | Other | −Sell | 34,556 | $171.80 | $6M |
| 2025-11-25 | Baker Cary | Officer | −Gift | 1,000 | — | — |
| 2025-11-25 | SYLEBRA CAPITAL LLC | Other | −Sell | 46,110 | $167.73 | $8M |
| 2025-11-24 | SYLEBRA CAPITAL LLC | Other | −Sell | 31,952 | $159.42 | $5M |
| 2025-11-21 | SYLEBRA CAPITAL LLC | Other | −Sell | 3,046 | $155.10 | $472,435 |
| 2025-11-20 | SYLEBRA CAPITAL LLC | Other | −Sell | 8,081 | $156.32 | $1M |
| 2025-11-19 | DIORIO CHRIS PH.D. | Director,Officer | −Gift | 7,000 | — | — |
| 2025-11-12 | Gibson Daniel Patrick | Director | −Sell | 3,772 | $156.30 | $589,564 |
| 2025-11-11 | SYLEBRA CAPITAL LLC | Other | −Sell | 30,000 | $155.63 | $5M |
| 2025-11-07 | WASHINGTON MIRON | Director | −Sell | 342 | $158.94 | $54,357 |
| 2025-11-07 | SYLEBRA CAPITAL LLC | Other | −Sell | 6,246 | $162.16 | $1M |
| 2025-11-06 | Gibson Daniel Patrick | Director | −Sell | 23,157 | $171.95 | $4M |
| 2025-11-03 | Gibson Daniel Patrick | Director | −Sell | 1,513 | $202.01 | $305,641 |
| 2025-10-30 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 23,500 | $22.40 | $526,400 |
| 2025-09-23 | Baker Cary | Officer | +Exercise | 781 | — | — |
| 2025-09-23 | Baker Cary | Officer | +Exercise | 597 | — | — |
| 2025-09-23 | Baker Cary | Officer | +Exercise | 479 | — | — |
| 2025-09-23 | Baker Cary | Officer | −Tax w/h | 732 | $184.97 | $135,398 |
| 2025-09-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,224 | — | — |
| 2025-09-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 2,594 | — | — |
| 2025-09-23 | DIORIO CHRIS PH.D. | Director,Officer | −Tax w/h | 2,219 | $184.97 | $410,448 |
| 2025-09-23 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 1,818 | — | — |
| 2025-09-18 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 47,039 | $33.77 | $2M |
| 2025-09-18 | DIORIO CHRIS PH.D. | Director,Officer | +Exercise | 7,036 | $22.40 | $157,606 |
| 2025-09-16 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 1,073 | $187.52 | $201,209 |
| 2025-09-16 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 1,821 | $186.43 | $339,489 |
| 2025-09-16 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 12 | $191.76 | $2,301 |
| 2025-09-16 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 850 | $189.21 | $160,829 |
| 2025-09-16 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 340 | $190.26 | $64,688 |
| 2025-09-15 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 796 | $183.47 | $146,042 |
| 2025-09-15 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 1,909 | $181.84 | $347,133 |
| 2025-09-15 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 467 | $180.65 | $84,364 |
| 2025-09-15 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 568 | $179.26 | $101,820 |
| 2025-09-15 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 1,260 | $182.77 | $230,290 |
| 2025-09-12 | DIORIO CHRIS PH.D. | Director,Officer | −Gift | 30,000 | — | — |
| 2025-09-10 | SYLEBRA CAPITAL LLC | Other | −Sell | 300,000 | $196.24 | $59M |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 330 | $190.42 | $62,839 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 199 | $191.30 | $38,069 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 510 | $192.84 | $98,348 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 1,332 | $194.18 | $258,648 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 1,120 | $195.10 | $218,512 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 249 | $196.34 | $48,889 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 790 | $197.23 | $155,812 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 303 | $197.86 | $59,952 |
| 2025-09-09 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 167 | $199.77 | $33,362 |
| 2025-09-08 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 3,007 | $192.58 | $579,088 |
| 2025-09-08 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 1,893 | $191.81 | $363,096 |
| 2025-09-08 | DIORIO CHRIS PH.D. | Director,Officer | −Sell | 100 | $193.30 | $19,330 |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.