Health Care · Pharmaceutical Preparations · Nasdaq · CIK 1651308 · FYE Dec 31 · Prices AT CLOSE 2026-08-19 (USD) Last $376.86 · Day +2.09% · Mkt cap $545.6B · P/E (FY) 1942.9× · 1Y +20.6% · Off 52W high −2.2% · Vol (1Y) 42.1% Price2025-01-02 → 2026-08-19 ONC close: $184 on 2025-01-02 to $377 on 2026-08-19. Split-adj closes · 240 of 398 · price returnⓘ At a glance | Short interest0.1% of sh out | | Days to cover2.4d | | 13F net flow (QoQ)−0.04% | | Top-10 13F concentration78.6% | | Next report (est.)2026-11-04 |
SI 2026-07-31 · 13F 2026-Q1ⓘ Key fundamentalsFY 2025 | P/E (FY)1942.9× | | Sales (TTM)$6.13B | | Earnings (TTM)$655.7M | | ROE7.5% | | Net margin5.4% | | ROIC24.1% | | Debt / equity0.23× | | Total debt / EBITDA1.73× | | Sales growth 3Y55.7% |
FY ratios · TTM sales/earnings (USD)ⓘ Trailing returns | YTD+24.0% | | 1Y+20.6% | | Since incept. (ann.)+55.4% |
Total return · from 2025-01-02ⓘ Risk | Ann. volatility (1Y)42.1% | | Ann. volatility (3Y)44.8% | | Sharpe (1Y)0.62 | | Sharpe (3Y)1.24 | | Max drawdown (1Y)−31.0% | | Max drawdown (3Y)−31.0% | | Beta (3Y vs SPY)0.25 |
Daily returns, ann.ⓘ Top institutional holders13F 2026-Q1 | Manager | Shares | Value | % sh out | QoQ |
|---|
| BAKER BROS. ADVISORS LP | 8.8M | $2.6B | 0.61% | +0.0% | | PRIMECAP MANAGEMENT CO/CA/ | 5.0M | $1.5B | 0.34% | −0.1% | | Capital International Investors | 4.2M | $1.2B | 0.29% | −18.7% | | FMR LLC | 3.7M | $1.1B | 0.26% | −7.5% | | Capital World Investors | 1.6M | $482M | 0.11% | new | | HHLR ADVISORS, LTD. | 1.0M | $307M | 0.07% | +0.0% | | CITADEL ADVISORS LLC | 1.0M | $307M | 0.07% | +93.5% | | Temasek Holdings (Private) Ltd | 862,643 | $256M | 0.06% | −6.2% |
Δ vs 2025-Q4ⓘ Latest reported quarterslast report 2026-08-05 | Period end | Reported | EPS | EPS YoY | Revenue | Rev YoY |
|---|
| 2026-06-30 | 2026-08-05 | $0.16 | +166.7% | $1.71B | +29.6% | | 2026-03-31 | 2026-05-06 | $0.15 | — | $1.51B | +35.5% | | 2025-12-31 | 2026-02-26 | — | — | $1.50B | +32.8% | | 2025-09-30 | 2025-11-06 | $0.08 | — | $1.41B | +41.0% |
As-reported XBRL · next 2026-11-04 est.ⓘ Segment mixFY2025 (ended Dec 2025) US 54% · CN 31% · Europe 11% · All Other Countries Except China United States Of America And Switzerland 3% geographic · TAGGED revenueⓘ Basis & disclosures - EOD closes · nothing imputed or averaged · absent “—”
- As-of differs by block · 13F = US long, 45+d lag, LOWER bound
- Not investment advice · no recommendation, price target or solicitation
- EDGAR + foreign registers · marketstack (licensed EOD) · spzco.com/methodology
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