Health Care · Biological Products, (No Diagnostic Substances) · Nasdaq · CIK 1754068 · FYE Dec 31 · Prices AT CLOSE 2026-08-21 (USD) Last $4.15 · Day +0.73% · Mkt cap $99M · 1Y +68.7% · Off 52W high −65.1% · Vol (1Y) 112.9% Price2025-03-19 → 2026-08-21 KLRS close: $11.5 on 2025-03-19 to $4.2 on 2026-08-21. Split-adj closes · 240 of 349 · price returnⓘ At a glance | Short interest1.7% of sh out | | Days to cover1.0d | | 13F net flow (QoQ)+3.09% | | Top-10 13F concentration92.2% | | Next report (est.)2026-11-10 |
SI 2026-07-31 · 13F 2026-Q1ⓘ Key fundamentalsFY 2025 FY ratios · TTM sales/earnings (USD)ⓘ Trailing returns | YTD−50.8% | | 1Y+68.7% | | Since incept. (ann.)−51.0% |
Total return · from 2025-03-19ⓘ Risk | Ann. volatility (1Y)112.9% | | Ann. volatility (3Y)104.2% | | Sharpe (1Y)0.99 | | Sharpe (3Y)−0.20 | | Max drawdown (1Y)−69.6% | | Max drawdown (3Y)−80.2% | | Beta (3Y vs SPY)0.17 |
Daily returns, ann.ⓘ Top institutional holders13F 2026-Q1 | Manager | Shares | Value | % sh out | QoQ |
|---|
| SAMSARA BIOCAPITAL, LLC | 12.9M | $75M | 56.47% | +0.0% | | RTW INVESTMENTS, LP | 1.3M | $8M | 5.67% | +0.0% | | Paradigm Biocapital Advisors LP | 700,000 | $4M | 3.05% | +0.0% | | Alyeska Investment Group, L.P. | 572,687 | $3M | 2.50% | +41.9% | | Siren, L.L.C. | 435,798 | $3M | 1.90% | +0.0% | | Ikarian Capital, LLC | 360,000 | $2M | 1.57% | +0.0% | | Propel Bio Management, LLC | 295,771 | $2M | 1.29% | +603.3% | | Kalehua Capital Management LLC | 271,170 | $2M | 1.18% | +93.8% |
Δ vs 2025-Q4ⓘ Latest reported quarterslast report 2026-08-11 | Period end | Reported | EPS | EPS YoY | Revenue | Rev YoY |
|---|
| 2026-06-30 | 2026-08-11 | −$0.48 | — | — | — | | 2026-03-31 | 2026-05-12 | −$0.46 | — | — | — | | 2025-09-30 | 2025-11-12 | −$0.64 | — | — | — | | 2025-06-30 | 2025-08-13 | −$0.61 | — | — | — |
As-reported XBRL · next 2026-11-10 est.ⓘ Basis & disclosures - EOD closes · nothing imputed or averaged · absent “—”
- As-of differs by block · 13F = US long, 45+d lag, LOWER bound
- Not investment advice · no recommendation, price target or solicitation
- EDGAR + foreign registers · marketstack (licensed EOD) · spzco.com/methodology
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