Health Care · Pharmaceutical Preparations · Nasdaq · CIK 1446847 · FYE Dec 31 · Prices AT CLOSE 2026-08-19 (USD) Last $4.36 · Day +1.16% · Mkt cap $712M · P/E (FY) 28.7× · 1Y +307.5% · Off 52W high −24.6% · Vol (1Y) 97.7% Price2023-08-21 → 2026-08-19 IRWD close: $9.7 on 2023-08-21 to $4.4 on 2026-08-19. Split-adj closes · 240 of 4,158 · price returnⓘ At a glance | Short interest10.0% of sh out | | Days to cover10.0d | | 13F net flow (QoQ)+5.76% | | Top-10 13F concentration54.9% | | Next report (est.)2026-11-05 |
SI 2026-07-31 · 13F 2026-Q1ⓘ Key fundamentalsFY 2025 | P/E (FY)28.7× | | Sales (TTM)$389.3M | | Earnings (TTM)$129.9M | | Net margin8.1% | | EPS growth 3Y−46.1% | | Sales growth 3Y−10.3% |
FY ratios · TTM sales/earnings (USD)ⓘ Trailing returns | YTD+29.4% | | 1Y+307.5% | | 3Y−55.1% | | 5Y−66.5% | | 10Y−61.4% | | Since incept. (ann.)−4.8% |
Total return · from 2010-02-03ⓘ Risk | Ann. volatility (1Y)97.7% | | Ann. volatility (3Y)92.6% | | Sharpe (1Y)1.86 | | Sharpe (3Y)0.18 | | Max drawdown (1Y)−43.6% | | Max drawdown (3Y)−96.3% | | Beta (3Y vs SPY)−0.09 |
Daily returns, ann.ⓘ Top institutional holders13F 2026-Q1 | Manager | Shares | Value | % sh out | QoQ |
|---|
| ARMISTICE CAPITAL, LLC | 15.0M | $53M | 9.22% | −6.2% | | BlackRock, Inc. | 13.4M | $47M | 8.20% | +4.5% | | Sarissa Capital Management LP | 9.2M | $32M | 5.64% | −42.3% | | BANK OF AMERICA CORP /DE/ | 8.7M | $30M | 5.33% | −24.6% | | RENAISSANCE TECHNOLOGIES LLC | 8.1M | $28M | 4.94% | −1.8% | | AQR CAPITAL MANAGEMENT LLC | 7.5M | $26M | 4.62% | +59.5% | | STATE STREET CORP | 7.5M | $26M | 4.57% | +69.0% | | VANGUARD PORTFOLIO MANAGEMENT LLC | 6.7M | $23M | 4.10% | new |
Δ vs 2025-Q4ⓘ Latest reported quarterslast report 2026-08-06 | Period end | Reported | EPS | EPS YoY | Revenue | Rev YoY |
|---|
| 2026-06-30 | 2026-08-06 | $0.31 | +121.4% | $113.0M | +32.6% | | 2026-03-31 | 2026-05-07 | $0.24 | — | $106.5M | +158.9% | | 2025-12-31 | 2026-02-25 | −$0.01 | −200.0% | $47.7M | −47.3% | | 2025-09-30 | 2025-11-10 | $0.23 | +1050.0% | $122.1M | +33.3% |
As-reported XBRL · next 2026-11-05 est.ⓘ Segment mixFY2025 (ended Dec 2025) Collaborative Arrangements 100% · Collaborative Arrangement Other Agreements 0% product & service · TAGGED revenueⓘ Basis & disclosures - EOD closes · nothing imputed or averaged · absent “—”
- As-of differs by block · 13F = US long, 45+d lag, LOWER bound
- Not investment advice · no recommendation, price target or solicitation
- EDGAR + foreign registers · marketstack (licensed EOD) · spzco.com/methodology
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