Item 1A Risk Factors 14
Item 1B Unresolved Staff Comments None
Item 2 Properties 11
Item 3 Legal Proceedings 27
Item 4 Mine Safety Disclosures Not Applicable
PART II
Item 7A Quantitative and Qualitative Disclosures About Market Risk 40
Item 8 Financial Statements and Supplementary Data 43
Item 9A Controls and Procedures 87
Item 9B Other Information None
PART III
Item 10 Directors, Executive Officers and Corporate Governance 89
Item 11 Executive Compensation 89
Item 14 Principal Accountant Fees and Services 90
PART IV
Item 15 Exhibits, Financial Statement Schedules 90
Signatures 96
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SIGNATURES
Pursuant to the requirements of the Section 13 or 15(d) of the Securities Exchange Act of 1934, the Registrant has duly caused this Report to be signed on its behalf by the undersigned, thereunto duly authorized, on February 18, 2022.
ILLUMINA, INC.
By /s/ FRANCIS A. DESOUZA
Francis A. deSouzaPresident and Chief Executive Officer
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February 18, 2022
POWER OF ATTORNEY
KNOW ALL PERSONS BY THESE PRESENT, that each person whose signature appears below constitutes and appoints Francis A. deSouza and Sam A. Samad, and each or any one of them, his or her true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him and in his or her name, place and stead, in any and all capacities, to sign any and all amendments to this Annual Report on Form 10-K, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their, his, or her substitutes or substitute, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Exchange Act of 1934, this Annual Report on Form 10-K has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.
Francis A. deSouza
Sam A. Samad
Jose Torres
/s/ JOHN W. THOMPSON Chairman of the Board of Directors February 18, 2022
John W. Thompson
/s/ FRANCES ARNOLD Director February 18, 2022
Frances Arnold, Ph.D.
/s/ CAROLINE D. DORSA Director February 18, 2022
Caroline D. Dorsa
/s/ ROBERT S. EPSTEIN Director February 18, 2022
Robert S. Epstein, M.D.
/s/ SCOTT GOTTLIEB Director February 18, 2022
Scott Gottlieb, M.D.
/s/ GARY S. GUTHART Director February 18, 2022
Gary S. Guthart, Ph.D.
/s/ PHILIP W. SCHILLER Director February 18, 2022
Philip W. Schiller
/s/ SUSAN E. SIEGEL Director February 18, 2022
Susan E. Siegel
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