Health Care · Pharmaceutical Preparations · Nasdaq · CIK 1785530 · FYE Dec 31 · Prices AT CLOSE 2026-08-19 (USD) Last $0.41 · Day +0.07% · Mkt cap $20M · 1Y −67.8% · Off 52W high −82.8% · Vol (1Y) 105.0% Price2023-08-21 → 2026-08-19 HOWL close: $2.46 on 2023-08-21 to $0.41 on 2026-08-19. Split-adj closes · 240 of 957 · price returnⓘ At a glance | Short interest2.3% of sh out | | Days to cover1.3d | | 13F net flow (QoQ)−2.24% | | Top-10 13F concentration90.8% | | Next report (est.)2026-10-30 |
SI 2026-07-31 · 13F 2026-Q1ⓘ Key fundamentalsFY 2025 | Earnings (TTM)-$34.6M | | ROE−123.9% | | Debt / equity1.29× |
FY ratios · TTM sales/earnings (USD)ⓘ Trailing returns | YTD−35.4% | | 1Y−67.8% | | 3Y−83.4% | | Since incept. (ann.)−45.3% |
Total return · from 2022-10-18ⓘ Risk | Ann. volatility (1Y)105.0% | | Ann. volatility (3Y)106.8% | | Sharpe (1Y)−0.59 | | Sharpe (3Y)−0.05 | | Max drawdown (1Y)−85.9% | | Max drawdown (3Y)−96.1% | | Beta (3Y vs SPY)0.59 |
Daily returns, ann.ⓘ Top institutional holders13F 2026-Q1 | Manager | Shares | Value | % sh out | QoQ |
|---|
| RA CAPITAL MANAGEMENT, L.P. | 6.7M | $6M | 13.75% | +0.0% | | VANGUARD CAPITAL MANAGEMENT LLC | 1.2M | $1M | 2.51% | new | | MPM BIOIMPACT LLC | 1.2M | $1M | 2.49% | −13.3% | | Lynx1 Capital Management LP | 657,786 | $547,673 | 1.35% | +0.3% | | SPHERA FUNDS MANAGEMENT LTD. | 626,810 | $521,882 | 1.29% | +0.0% | | DC Funds, LP | 589,102 | $490,486 | 1.21% | +0.0% | | Squadron Capital Management LLC | 563,535 | $469,199 | 1.16% | new | | RENAISSANCE TECHNOLOGIES LLC | 516,218 | $429,803 | 1.06% | −23.8% |
Δ vs 2025-Q4ⓘ Latest reported quarterslast report 2026-07-31 | Period end | Reported | EPS | EPS YoY | Revenue | Rev YoY |
|---|
| 2026-06-30 | 2026-07-31 | $0.08 | — | — | — | | 2026-03-31 | 2026-05-07 | −$0.28 | — | — | — | | 2025-09-30 | 2025-11-04 | −$0.36 | — | — | — | | 2025-06-30 | 2025-08-14 | −$0.40 | — | — | — |
As-reported XBRL · next 2026-10-30 est.ⓘ Basis & disclosures - EOD closes · nothing imputed or averaged · absent “—”
- As-of differs by block · 13F = US long, 45+d lag, LOWER bound
- Not investment advice · no recommendation, price target or solicitation
- EDGAR + foreign registers · marketstack (licensed EOD) · spzco.com/methodology
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