Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-10 | Altmeyer Anne | Director | −Sell | 2,412 | $7.91 | $19,079 |
| 2026-06-10 | Jenkins John Kenneth | Director | −Sell | 4,800 | $7.91 | $37,968 |
| 2026-06-10 | Kung Winston | Director | −Sell | 2,026 | $7.91 | $16,026 |
| 2026-06-03 | Saxena Nishant C | Officer | +Buy | 9,000 | $7.58 | $68,220 |
| 2026-06-02 | Saxena Nishant C | Officer | +Buy | 4,500 | $7.33 | $32,985 |
| 2026-05-21 | Saxena Nishant C | Officer | +Grant | 58,300 | — | — |
| 2026-05-19 | Pfeiffenberger Brent | Director | +Grant | 7,500 | — | — |
| 2026-05-19 | Ben Yong | Director | +Grant | 3,800 | — | — |
| 2026-05-19 | Altmeyer Anne | Director | +Grant | 3,800 | — | — |
| 2026-05-19 | Jenkins John Kenneth | Director | +Grant | 3,800 | — | — |
| 2026-05-19 | Jacques Rachelle Suzanne | Director | +Grant | 3,800 | — | — |
| 2026-05-19 | Kung Winston | Director | +Grant | 3,800 | — | — |
| 2026-03-02 | Smethurst Dominic | Officer | −Sell | 6,097 | $8.30 | $50,605 |
| 2026-02-17 | Hodgson Ian | Officer | −Sell | 847 | $7.38 | $6,251 |
| 2026-02-13 | Cohen Yuval | Director,Officer | −Sell | 13,871 | $7.78 | $107,916 |
| 2026-02-13 | Moran Sean F. | Officer | −Sell | 4,701 | $7.78 | $36,574 |
| 2026-02-03 | Hodgson Ian | Officer | −Sell | 2,415 | $8.09 | $19,537 |
| 2026-02-03 | Smethurst Dominic | Officer | −Sell | 3,285 | $8.09 | $26,576 |
| 2026-01-14 | Cohen Yuval | Director,Officer | +Grant | 50,000 | — | — |
| 2026-01-14 | Moran Sean F. | Officer | +Grant | 28,082 | — | — |
| 2026-01-14 | Smethurst Dominic | Officer | +Grant | 28,365 | — | — |
| 2026-01-14 | Hodgson Ian | Officer | +Grant | 28,365 | — | — |
| 2025-12-11 | Chen Bihua | TenPercentOwner | −Sell | 30,029 | $11.46 | $344,132 |
| 2025-10-27 | Cohen Yuval | Director,Officer | +Exercise | 8,973 | $4.26 | $38,225 |
| 2025-10-27 | Cohen Yuval | Director,Officer | −Sell | 8,973 | $17.14 | $153,797 |
| 2025-10-24 | Moran Sean F. | Officer | +Exercise | 12,981 | $4.26 | $55,299 |
| 2025-10-24 | Moran Sean F. | Officer | −Sell | 12,981 | $17.02 | $220,937 |
| 2025-10-24 | Cohen Yuval | Director,Officer | +Exercise | 18,660 | $4.26 | $79,492 |
| 2025-10-24 | Cohen Yuval | Director,Officer | −Sell | 18,660 | $17.01 | $317,407 |
| 2025-10-20 | Altmeyer Anne | Director | −Sell | 1,060 | $20.50 | $21,730 |
| 2025-10-20 | Altmeyer Anne | Director | +Exercise | 1,060 | $4.80 | $5,088 |
| 2025-05-30 | Jacques Rachelle Suzanne | Director | +Grant | 4,800 | — | — |
| 2025-05-30 | HOLMER ALAN F | Director | +Grant | 4,800 | — | — |
| 2025-05-30 | Altmeyer Anne | Director | +Grant | 4,800 | — | — |
| 2025-05-30 | Altmeyer Anne | Director | −Sell | 1,392 | $7.25 | $10,092 |
| 2025-05-30 | Ben Yong | Director | +Grant | 4,800 | — | — |
| 2025-05-30 | Jenkins John Kenneth | Director | −Sell | 2,783 | $7.35 | $20,455 |
| 2025-05-30 | Jenkins John Kenneth | Director | +Grant | 4,800 | — | — |
| 2025-05-30 | Kung Winston | Director | +Grant | 4,800 | — | — |
| 2025-03-06 | Smethurst Dominic | Officer | −Sell | 6,393 | $6.78 | $43,345 |
| 2025-02-14 | Cohen Yuval | Director,Officer | −Sell | 7,134 | $8.76 | $62,494 |
| 2025-02-14 | Moran Sean F. | Officer | −Sell | 2,792 | $8.76 | $24,458 |
| 2025-01-31 | Cohen Yuval | Director,Officer | +Grant | 68,100 | — | — |
| 2025-01-31 | Moran Sean F. | Officer | +Grant | 27,500 | — | — |
| 2025-01-31 | Smethurst Dominic | Officer | +Grant | 27,200 | — | — |
| 2024-09-20 | Cormorant Global Healthcare Master Fund, LP | TenPercentOwner | +Buy | 47,564 | $21.47 | $1M |
| 2024-09-20 | Cormorant Global Healthcare Master Fund, LP | TenPercentOwner | +Buy | 66,088 | $19.61 | $1M |
| 2024-09-20 | Cormorant Global Healthcare Master Fund, LP | TenPercentOwner | +Buy | 139,551 | $20.42 | $3M |
| 2024-09-20 | Cormorant Global Healthcare Master Fund, LP | TenPercentOwner | +Buy | 25,769 | $22.23 | $572,845 |
| 2024-09-20 | Cormorant Global Healthcare Master Fund, LP | TenPercentOwner | +Buy | 45,085 | $17.48 | $788,086 |
| 2024-09-20 | Cormorant Global Healthcare Master Fund, LP | TenPercentOwner | +Buy | 25,943 | $18.36 | $476,313 |
| 2024-08-16 | Kung Winston | Director | +Grant | 5,566 | — | — |
| 2024-06-18 | Cohen Yuval | Director,Officer | −Sell | 7,179 | $42.24 | $303,241 |
| 2024-06-18 | Cohen Yuval | Director,Officer | +Exercise | 1,770 | $14.10 | $24,957 |
| 2024-06-18 | Cohen Yuval | Director,Officer | −Sell | 1,770 | $42.24 | $74,765 |
| 2024-06-18 | Cohen Yuval | Director,Officer | +Exercise | 2,322 | $4.26 | $9,892 |
| 2024-06-18 | Cohen Yuval | Director,Officer | −Sell | 2,322 | $42.24 | $98,081 |
| 2024-06-18 | Cohen Yuval | Director,Officer | −Sell | 11,667 | $42.24 | $492,814 |
| 2024-06-18 | Cohen Yuval | Director,Officer | +Exercise | 11,667 | $30.00 | $350,010 |
| 2024-06-18 | Moran Sean F. | Officer | −Sell | 1,958 | $42.12 | $82,471 |
| 2024-06-18 | Moran Sean F. | Officer | +Exercise | 1,958 | $30.00 | $58,740 |
| 2024-06-17 | Cohen Yuval | Director,Officer | +Exercise | 9,333 | $30.00 | $279,990 |
| 2024-06-17 | Cohen Yuval | Director,Officer | −Sell | 1,770 | $46.02 | $81,455 |
| 2024-06-17 | Cohen Yuval | Director,Officer | −Sell | 9,333 | $46.02 | $429,505 |
| 2024-06-17 | Cohen Yuval | Director,Officer | +Exercise | 1,770 | $4.26 | $7,540 |
| 2024-06-17 | Moran Sean F. | Officer | +Exercise | 6,730 | $14.10 | $94,893 |
| 2024-06-17 | Moran Sean F. | Officer | −Sell | 6,730 | $46.77 | $314,762 |
| 2024-06-14 | HOLMER ALAN F | Director | +Exercise | 1,667 | $30.00 | $50,010 |
| 2024-06-14 | Cohen Yuval | Director,Officer | +Exercise | 16,830 | $14.10 | $237,303 |
| 2024-06-14 | Cohen Yuval | Director,Officer | −Sell | 16,830 | $50.17 | $844,361 |
| 2024-06-14 | Cohen Yuval | Director,Officer | +Exercise | 12,487 | $4.26 | $53,195 |
| 2024-06-14 | Cohen Yuval | Director,Officer | −Sell | 12,487 | $50.17 | $626,473 |
| 2024-06-14 | Moran Sean F. | Officer | +Exercise | 7,788 | $4.26 | $33,177 |
| 2024-06-14 | Moran Sean F. | Officer | +Exercise | 1,567 | $30.00 | $47,010 |
| 2024-06-14 | Moran Sean F. | Officer | −Sell | 1,567 | $49.87 | $78,146 |
| 2024-06-14 | Moran Sean F. | Officer | −Sell | 7,788 | $49.87 | $388,388 |
| 2024-05-30 | Altmeyer Anne | Director | +Grant | 2,783 | — | — |
| 2024-05-30 | HOLMER ALAN F | Director | +Grant | 2,783 | — | — |
| 2024-05-30 | Ben Yong | Director | +Grant | 2,783 | — | — |
| 2024-05-30 | Jacques Rachelle Suzanne | Director | +Grant | 2,783 | — | — |
| 2024-05-30 | Salzmann Peter | Director | +Grant | 2,783 | — | — |
| 2024-05-30 | CATLIN AVERY W | Director | +Grant | 2,783 | — | — |
| 2024-05-30 | Jenkins John Kenneth | Director | +Grant | 2,783 | — | — |
| 2024-04-10 | Moran Sean F. | Officer | +Exercise | 1,787 | $30.00 | $53,610 |
| 2024-03-08 | Chen Bihua | TenPercentOwner | +Buy | 29,342 | $41.23 | $1M |
| 2024-03-08 | Chen Bihua | TenPercentOwner | +Buy | 156,597 | $45.26 | $7M |
| 2024-03-08 | Chen Bihua | TenPercentOwner | +Buy | 8,862 | $45.96 | $407,298 |
| 2024-03-08 | Chen Bihua | TenPercentOwner | +Buy | 18,548 | $43.26 | $802,386 |
| 2024-03-08 | Chen Bihua | TenPercentOwner | +Buy | 61,668 | $44.62 | $3M |
| 2024-03-08 | Chen Bihua | TenPercentOwner | +Buy | 24,983 | $42.25 | $1M |
| 2024-03-07 | Chen Bihua | TenPercentOwner | +Buy | 102,140 | $41.23 | $4M |
| 2024-03-07 | Chen Bihua | TenPercentOwner | +Buy | 46,799 | $37.82 | $2M |
| 2024-03-07 | Chen Bihua | TenPercentOwner | +Buy | 10,736 | $39.13 | $420,100 |
| 2024-03-07 | Chen Bihua | TenPercentOwner | +Buy | 90,325 | $39.99 | $4M |
| 2024-02-27 | Smethurst Dominic | Officer | +Grant | 50,000 | — | — |
| 2024-02-12 | Cohen Yuval | Director,Officer | +Grant | 73,947 | — | — |
| 2024-02-12 | Moran Sean F. | Officer | +Grant | 40,176 | — | — |
| 2024-02-02 | Cormorant Asset Management, LP | TenPercentOwner | +Buy | 750,000 | $19.00 | $14M |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 16,484 | $36.53 | $602,161 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 32,295 | $35.83 | $1M |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 31,549 | $34.62 | $1M |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 18,055 | $33.71 | $608,634 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 3,866 | $32.47 | $125,529 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 4,125 | $31.86 | $131,423 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 2,654 | $31.00 | $82,274 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 43,754 | $37.49 | $2M |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 3,200 | $38.49 | $123,168 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 29,244 | $29.42 | $860,358 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 14,388 | $25.73 | $370,203 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 15,243 | $26.66 | $406,378 |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 36,747 | $27.70 | $1M |
| 2024-01-26 | Chen Bihua | TenPercentOwner | +Buy | 31,028 | $28.82 | $894,227 |
| 2024-01-26 | Cohen Yuval | Director,Officer | +Exercise | 7,179 | $4.97 | $35,680 |
| 2024-01-26 | HOLMER ALAN F | Director | +Exercise | 629 | $4.97 | $3,126 |
| 2022-08-10 | Moran Sean F. | Officer | +Buy | 20,000 | $0.26 | $5,200 |
| 2022-08-10 | Cohen Yuval | Director,Officer | +Buy | 3,800 | $0.26 | $988 |
| 2022-08-10 | Millian Craig Stuart | Officer | +Buy | 5,000 | $0.25 | $1,250 |
| 2022-05-16 | Cohen Yuval | Director,Officer | +Buy | 10,500 | $0.25 | $2,625 |
| 2022-05-16 | Moran Sean F. | Officer | +Buy | 12,000 | $0.30 | $3,600 |
| 2022-03-10 | Moran Sean F. | Officer | +Buy | 15,000 | $0.37 | $5,550 |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
