Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-16 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 61,523 | $24.98 | $2M |
| 2026-06-15 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 6,146 | $24.89 | $152,974 |
| 2026-05-20 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 996 | $24.94 | $24,840 |
| 2026-05-19 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 3,802 | $24.97 | $94,936 |
| 2026-05-12 | Kolchinsky Peter | TenPercentOwner | +Buy | 6,387 | $24.90 | $159,036 |
| 2026-05-11 | RA Capital Healthcare Fund LP | TenPercentOwner | +Buy | 14,149 | $24.47 | $346,226 |
| 2026-05-11 | RA Capital Healthcare Fund LP | TenPercentOwner | +Buy | 25,720 | $25.00 | $643,000 |
| 2026-05-08 | RA Capital Healthcare Fund LP | TenPercentOwner | +Buy | 1,483 | $24.98 | $37,045 |
| 2026-05-07 | RA Capital Healthcare Fund LP | TenPercentOwner | +Buy | 7,921 | $24.34 | $192,797 |
| 2026-05-07 | RA Capital Healthcare Fund LP | TenPercentOwner | +Buy | 1,985 | $24.95 | $49,526 |
| 2026-05-06 | Shah Rajeev M. | Director,TenPercentOwner | +Buy | 14,611 | $23.77 | $347,303 |
| 2026-05-06 | Shah Rajeev M. | Director,TenPercentOwner | +Buy | 53,407 | $24.83 | $1M |
| 2026-05-05 | Shah Rajeev M. | Director,TenPercentOwner | +Buy | 87,143 | $24.59 | $2M |
| 2026-05-05 | Shah Rajeev M. | Director,TenPercentOwner | +Buy | 10,268 | $25.00 | $256,700 |
| 2026-05-04 | MARAGANORE JOHN | Director | +Conversion | 17,974 | — | — |
| 2026-05-04 | MARAGANORE JOHN | Director | +Conversion | 17,974 | — | — |
| 2026-05-04 | Novo Holdings A/S | TenPercentOwner | +Conversion | 4,180,550 | — | — |
| 2026-05-04 | Shah Rajeev M. | Director,TenPercentOwner | +Conversion | 1,009,052 | — | — |
| 2026-05-04 | Shah Rajeev M. | Director,TenPercentOwner | +Conversion | 221,188 | — | — |
| 2026-05-04 | Shah Rajeev M. | Director,TenPercentOwner | +Buy | 2,541,250 | $18.00 | $46M |
| 2026-05-04 | Shah Rajeev M. | Director,TenPercentOwner | +Buy | 133,750 | $18.00 | $2M |
| 2026-05-04 | Shah Rajeev M. | Director,TenPercentOwner | +Conversion | 3,607,846 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
