Health Care · Biological Products, (No Diagnostic Substances) · Nasdaq · CIK 1314052 · FYE Sep 30 · Prices AT CLOSE 2026-08-19 (USD) Last $3.39 · Day +5.94% · Mkt cap $297M · 1Y −64.1% · Off 52W high −67.4% · Vol (1Y) 86.8% Price2023-08-21 → 2026-08-19 AVXL close: $8.2 on 2023-08-21 to $3.4 on 2026-08-19. Split-adj closes · 240 of 5,037 · price returnⓘ At a glance | Short interest15.6% of sh out | | Days to cover14.4d | | 13F net flow (QoQ)+4.64% | | Top-10 13F concentration65.1% | | Next report (est.)2026-11-09 |
SI 2026-07-31 · 13F 2026-Q1ⓘ Key fundamentalsFY 2025 | Earnings (TTM)-$39.9M | | ROE−43.1% |
FY ratios · TTM sales/earnings (USD)ⓘ Trailing returns | YTD−4.8% | | 1Y−64.1% | | 3Y−58.5% | | 5Y−81.5% | | 10Y+5.6% | | Since incept. (ann.)−4.2% |
Total return · from 2006-08-02ⓘ Risk | Ann. volatility (1Y)86.8% | | Ann. volatility (3Y)82.0% | | Sharpe (1Y)−0.73 | | Sharpe (3Y)0.07 | | Max drawdown (1Y)−77.2% | | Max drawdown (3Y)−82.6% | | Beta (3Y vs SPY)2.02 |
Daily returns, ann.ⓘ Top institutional holders13F 2026-Q1 | Manager | Shares | Value | % sh out | QoQ |
|---|
| BlackRock, Inc. | 7.6M | $23M | 8.21% | +1.1% | | STATE STREET CORP | 4.5M | $14M | 4.87% | +2.9% | | VANGUARD CAPITAL MANAGEMENT LLC | 3.9M | $12M | 4.17% | new | | TWO SIGMA INVESTMENTS, LP | 3.2M | $10M | 3.50% | +96.4% | | GEODE CAPITAL MANAGEMENT, LLC | 2.2M | $7M | 2.36% | +8.2% | | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 995,663 | $3M | 1.07% | +126.5% | | Summit Financial, LLC | 940,455 | $3M | 1.01% | +4.1% | | BANK OF AMERICA CORP /DE/ | 863,150 | $3M | 0.93% | +64.7% |
Δ vs 2025-Q4ⓘ Latest reported quarterslast report 2026-02-09 | Period end | Reported | EPS | EPS YoY | Revenue | Rev YoY |
|---|
| 2025-12-31 | 2026-02-09 | −$0.06 | — | — | — | | 2025-06-30 | 2025-08-12 | −$0.16 | — | — | — | | 2025-03-31 | 2025-05-13 | −$0.13 | — | — | — | | 2024-12-31 | 2025-02-12 | −$0.14 | — | — | — |
As-reported XBRL · next 2026-11-09 est.ⓘ Basis & disclosures - EOD closes · nothing imputed or averaged · absent “—”
- As-of differs by block · 13F = US long, 45+d lag, LOWER bound
- Not investment advice · no recommendation, price target or solicitation
- EDGAR + foreign registers · marketstack (licensed EOD) · spzco.com/methodology
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