Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-05-21 | Masson Kristina | Director,Officer | −Tax w/h | 13,729 | $1.79 | $24,575 |
| 2026-05-18 | Blume-Jensen Peter | Director,Officer | +Grant | 180,095 | — | — |
| 2026-05-18 | Blume-Jensen Peter | Director,Officer | +Grant | 72,706 | — | — |
| 2026-05-18 | Devroe Eric | Officer | +Grant | 72,981 | — | — |
| 2026-05-18 | Gamelin Erick | Officer | +Grant | 38,584 | — | — |
| 2026-05-18 | Levy Adam D. | Officer | +Grant | 46,167 | — | — |
| 2026-05-18 | Miller Mary | Officer | +Grant | 49,830 | — | — |
| 2026-05-18 | Mirza Mansoor Raza | Officer | +Grant | 38,817 | — | — |
| 2026-05-18 | Peterson Katharine | Officer | +Grant | 14,227 | — | — |
| 2026-05-18 | BAUM CHARLES M | Director | +Grant | 9,366 | — | — |
| 2026-05-18 | DiRocco Derek | Director | +Grant | 9,366 | — | — |
| 2026-05-18 | Magovcevic-Liebisch Ivana | Director | +Grant | 9,366 | — | — |
| 2026-05-18 | Palani Santhosh | Director | +Grant | 9,366 | — | — |
| 2026-05-18 | Shacham Sharon | Director | +Grant | 9,366 | — | — |
| 2026-05-18 | TOMSICEK MICHAEL JOHN | Director | +Grant | 9,366 | — | — |
| 2026-05-18 | RA Capital Nexus Fund II, L.P. | Director | +Grant | 9,366 | — | — |
| 2026-05-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 490 | $1.92 | $941 |
| 2026-05-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 1,253 | $1.92 | $2,406 |
| 2026-05-14 | Devroe Eric | Officer | −Tax w/h | 613 | $1.92 | $1,177 |
| 2026-05-14 | Gamelin Erick | Officer | −Tax w/h | 404 | $1.92 | $776 |
| 2026-05-14 | Miller Mary | Officer | −Tax w/h | 184 | $1.92 | $353 |
| 2026-05-14 | Peterson Katharine | Officer | −Tax w/h | 99 | $1.92 | $190 |
| 2026-04-22 | RA Capital Nexus Fund II, L.P. | Director | +Grant | 3,888,888 | $1.80 | $7M |
| 2026-04-17 | Miller Mary | Officer | −Tax w/h | 558 | $1.78 | $993 |
| 2026-02-21 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 14,265 | $1.53 | $21,825 |
| 2026-02-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 1,302 | $1.63 | $2,122 |
| 2026-02-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 579 | $1.63 | $944 |
| 2026-02-14 | Devroe Eric | Officer | −Tax w/h | 723 | $1.63 | $1,178 |
| 2026-02-14 | Gamelin Erick | Officer | −Tax w/h | 471 | $1.63 | $768 |
| 2026-02-14 | Miller Mary | Officer | −Tax w/h | 217 | $1.63 | $354 |
| 2026-02-14 | Peterson Katharine | Officer | −Tax w/h | 116 | $1.63 | $189 |
| 2026-01-17 | Miller Mary | Officer | −Tax w/h | 659 | $1.98 | $1,305 |
| 2026-01-14 | Levy Adam D. | Officer | +Buy | 8,832 | $1.70 | $15,014 |
| 2026-01-14 | Blume-Jensen Peter | Director,Officer | +Buy | 49,000 | $1.68 | $82,320 |
| 2026-01-13 | Devroe Eric | Officer | +Buy | 10,000 | $1.72 | $17,200 |
| 2025-11-21 | Masson Kristina | Director,Officer | −Tax w/h | 19,904 | $2.30 | $45,779 |
| 2025-11-14 | Masson Kristina | Director,Officer | −Tax w/h | 59,765 | $2.24 | $133,874 |
| 2025-11-14 | Masson Kristina | Director,Officer | −Tax w/h | 490 | $2.24 | $1,098 |
| 2025-11-14 | Devroe Eric | Officer | −Tax w/h | 613 | $2.24 | $1,373 |
| 2025-11-14 | Gamelin Erick | Officer | −Tax w/h | 403 | $2.24 | $903 |
| 2025-11-14 | Miller Mary | Officer | −Tax w/h | 184 | $2.24 | $412 |
| 2025-11-14 | Peterson Katharine | Officer | −Tax w/h | 99 | $2.24 | $222 |
| 2025-10-17 | Miller Mary | Officer | −Tax w/h | 558 | $1.81 | $1,010 |
| 2025-10-01 | Miller Mary | Officer | −Tax w/h | 284 | $1.81 | $514 |
| 2025-08-21 | Masson Kristina | Director,Officer | −Tax w/h | 19,905 | $1.32 | $26,275 |
| 2025-08-14 | Masson Kristina | Director,Officer | −Tax w/h | 59,766 | $1.39 | $83,075 |
| 2025-08-14 | Masson Kristina | Director,Officer | −Tax w/h | 490 | $1.39 | $681 |
| 2025-08-14 | Devroe Eric | Officer | −Tax w/h | 613 | $1.39 | $852 |
| 2025-08-14 | Gamelin Erick | Officer | −Tax w/h | 403 | $1.39 | $560 |
| 2025-08-14 | Miller Mary | Officer | −Tax w/h | 184 | $1.39 | $256 |
| 2025-08-14 | Peterson Katharine | Officer | −Tax w/h | 99 | $1.39 | $138 |
| 2025-08-01 | Levy Adam D. | Officer | −Tax w/h | 1,164 | $1.26 | $1,467 |
| 2025-07-17 | Miller Mary | Officer | −Tax w/h | 558 | $1.32 | $737 |
| 2025-05-21 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 19,904 | $1.15 | $22,890 |
| 2025-05-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 59,766 | $1.14 | $68,133 |
| 2025-05-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 491 | $1.14 | $560 |
| 2025-05-14 | Devroe Eric | Officer | −Tax w/h | 613 | $1.14 | $699 |
| 2025-05-14 | Gamelin Erick | Officer | −Tax w/h | 403 | $1.14 | $459 |
| 2025-05-14 | Miller Mary | Officer | −Tax w/h | 184 | $1.14 | $210 |
| 2025-05-14 | Peterson Katharine | Officer | −Tax w/h | 99 | $1.14 | $113 |
| 2025-05-01 | PERCEPTIVE ADVISORS LLC | TenPercentOwner | −Sell | 298,886 | $1.34 | $400,507 |
| 2025-04-30 | PERCEPTIVE ADVISORS LLC | TenPercentOwner | −Sell | 437,881 | $1.41 | $617,412 |
| 2025-04-29 | PERCEPTIVE ADVISORS LLC | TenPercentOwner | −Sell | 250,000 | $1.41 | $352,500 |
| 2025-04-28 | PERCEPTIVE ADVISORS LLC | TenPercentOwner | −Sell | 215,283 | $1.56 | $335,841 |
| 2025-04-25 | PERCEPTIVE ADVISORS LLC | TenPercentOwner | −Sell | 1,054,669 | $1.95 | $2M |
| 2025-04-17 | Miller Mary | Officer | −Tax w/h | 558 | $1.81 | $1,010 |
| 2025-02-21 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 19,904 | $5.54 | $110,268 |
| 2025-02-14 | Masson Kristina | Director,Officer | −Tax w/h | 579 | $5.42 | $3,138 |
| 2025-02-14 | Masson Kristina | Director,Officer | −Tax w/h | 37,152 | $5.42 | $201,364 |
| 2025-02-14 | Devroe Eric | Officer | −Tax w/h | 724 | $5.42 | $3,924 |
| 2025-02-14 | Gamelin Erick | Officer | −Tax w/h | 469 | $5.42 | $2,542 |
| 2025-02-14 | Holm-Jorgensen Rasmus | Officer | −Tax w/h | 434 | $5.42 | $2,352 |
| 2025-02-14 | Miller Mary | Officer | −Tax w/h | 217 | $5.42 | $1,176 |
| 2025-02-14 | Peterson Katharine | Officer | −Tax w/h | 116 | $5.42 | $629 |
| 2025-01-17 | Miller Mary | Officer | −Tax w/h | 659 | $5.78 | $3,809 |
| 2024-11-21 | Masson Kristina | Director,Officer | −Tax w/h | 19,910 | $6.44 | $128,220 |
| 2024-11-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 490 | $7.92 | $3,881 |
| 2024-11-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 59,766 | $7.92 | $473,347 |
| 2024-11-14 | Devroe Eric | Officer | −Tax w/h | 613 | $7.92 | $4,855 |
| 2024-11-14 | Gamelin Erick | Officer | −Tax w/h | 402 | $7.92 | $3,184 |
| 2024-11-14 | Holm-Jorgensen Rasmus | Officer | −Tax w/h | 368 | $7.92 | $2,915 |
| 2024-11-14 | Miller Mary | Officer | −Tax w/h | 184 | $7.92 | $1,457 |
| 2024-11-14 | Peterson Katharine | Officer | −Tax w/h | 99 | $7.92 | $784 |
| 2024-10-17 | Miller Mary | Officer | −Tax w/h | 558 | $7.87 | $4,391 |
| 2024-10-01 | Miller Mary | Officer | −Tax w/h | 284 | $6.98 | $1,982 |
| 2024-08-21 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 79,616 | $9.19 | $731,671 |
| 2024-08-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 59,765 | $7.02 | $419,550 |
| 2024-08-14 | Devroe Eric | Officer | −Tax w/h | 613 | $7.02 | $4,303 |
| 2024-08-14 | Gamelin Erick | Officer | −Tax w/h | 402 | $7.02 | $2,822 |
| 2024-08-14 | Holm-Jorgensen Rasmus | Officer | −Tax w/h | 368 | $7.02 | $2,583 |
| 2024-08-14 | Masson Kristina | Director,Officer | −Tax w/h | 490 | $7.02 | $3,440 |
| 2024-08-14 | Miller Mary | Officer | −Tax w/h | 184 | $7.02 | $1,292 |
| 2024-08-14 | Peterson Katharine | Officer | −Tax w/h | 99 | $7.02 | $695 |
| 2024-07-17 | Miller Mary | Officer | −Tax w/h | 558 | $7.69 | $4,291 |
| 2024-05-17 | Devroe Eric | Officer | +Exercise | 10,000 | $1.04 | $10,400 |
| 2024-05-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 54,918 | $8.36 | $459,114 |
| 2024-05-14 | Devroe Eric | Officer | −Tax w/h | 613 | $8.36 | $5,125 |
| 2024-05-14 | Gamelin Erick | Officer | −Tax w/h | 402 | $8.36 | $3,361 |
| 2024-05-14 | Holm-Jorgensen Rasmus | Officer | −Tax w/h | 368 | $8.36 | $3,076 |
| 2024-05-14 | Masson Kristina | Director,Officer | −Tax w/h | 490 | $8.36 | $4,096 |
| 2024-05-14 | Miller Mary | Officer | −Tax w/h | 184 | $8.36 | $1,538 |
| 2024-05-14 | Peterson Katharine | Officer | −Tax w/h | 99 | $8.36 | $828 |
| 2024-04-17 | Miller Mary | Officer | −Tax w/h | 558 | $10.34 | $5,770 |
| 2024-04-11 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | TenPercentOwner | +Buy | 2,353,000 | $8.50 | $20M |
| 2024-04-11 | RA Capital Healthcare Fund LP | Director,TenPercentOwner | +Grant | 3,530,000 | $8.50 | $30M |
| 2024-02-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 41,861 | $3.40 | $142,327 |
| 2024-02-14 | Devroe Eric | Officer | −Tax w/h | 723 | $3.40 | $2,458 |
| 2024-02-14 | Gamelin Erick | Officer | −Tax w/h | 468 | $3.40 | $1,591 |
| 2024-02-14 | Holm-Jorgensen Rasmus | Officer | −Tax w/h | 434 | $3.40 | $1,476 |
| 2024-02-14 | Masson Kristina | Director,Officer | −Tax w/h | 579 | $3.40 | $1,969 |
| 2024-02-14 | Miller Mary | Officer | −Tax w/h | 217 | $3.40 | $738 |
| 2024-01-17 | Miller Mary | Officer | −Tax w/h | 652 | $4.35 | $2,836 |
| 2023-11-14 | Blume-Jensen Peter | Director,Officer | −Tax w/h | 239,023 | $5.08 | $1M |
| 2023-11-14 | Devroe Eric | Officer | −Tax w/h | 2,450 | $5.08 | $12,446 |
| 2023-11-14 | Gamelin Erick | Officer | −Tax w/h | 1,395 | $5.08 | $7,087 |
| 2023-11-14 | Holm-Jorgensen Rasmus | Officer | −Tax w/h | 1,470 | $5.08 | $7,468 |
| 2023-11-14 | Masson Kristina | Director,Officer | −Tax w/h | 1,900 | $5.08 | $9,652 |
| 2023-11-14 | Miller Mary | Officer | −Tax w/h | 735 | $5.08 | $3,734 |
| 2023-10-17 | Miller Mary | Officer | −Tax w/h | 2,232 | $5.48 | $12,231 |
| 2023-09-26 | Miller Mary | Officer | +Grant | 3,858 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
