Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-17 | Porter Derrell | Director | +Exercise | 13,040 | $1.07 | $13,953 |
| 2026-06-17 | Porter Derrell | Director | −Sell | 13,040 | $2.33 | $30,383 |
| 2026-06-16 | Porter Derrell | Director | −Sell | 12,800 | $2.33 | $29,824 |
| 2026-06-15 | Porter Derrell | Director | −Sell | 6,460 | $2.35 | $15,181 |
| 2026-06-15 | Porter Derrell | Director | +Exercise | 6,460 | $1.07 | $6,912 |
| 2026-06-09 | Fountain Nathan B | Director | −Sell | 6,400 | $2.23 | $14,272 |
| 2026-06-03 | Stoppel Laura | Director | +Grant | 35,500 | — | — |
| 2026-06-03 | Golumbeski George | Director | +Grant | 35,500 | — | — |
| 2026-06-03 | Ives Jeffrey L. | Director | +Grant | 35,500 | — | — |
| 2026-06-03 | Porter Derrell | Director | +Grant | 35,500 | — | — |
| 2026-06-03 | Stalfort John A III | Director | +Grant | 35,500 | — | — |
| 2026-06-03 | Drapkin Kimberlee C | Director | +Grant | 35,500 | — | — |
| 2026-06-03 | Fountain Nathan B | Director | +Grant | 35,500 | — | — |
| 2026-06-03 | RA Capital Nexus Fund II, L.P. | Director | +Grant | 35,500 | — | — |
| 2026-03-16 | Shah Rajeev M. | Director,TenPercentOwner | +Grant | 6,060,606 | $3.30 | $20M |
| 2026-03-06 | Meisner Derek M | Officer | −Sell | 2,090 | $3.26 | $6,813 |
| 2026-03-06 | Meisner Derek M | Officer | +Exercise | 2,090 | $1.85 | $3,867 |
| 2026-02-27 | Meisner Derek M | Officer | −Sell | 9,406 | $3.01 | $28,312 |
| 2026-02-27 | Meisner Derek M | Officer | +Exercise | 9,406 | $1.85 | $17,401 |
| 2026-01-28 | Meisner Derek M | Officer | −Sell | 2,671 | $3.00 | $8,013 |
| 2026-01-28 | Meisner Derek M | Officer | +Exercise | 2,671 | $1.85 | $4,941 |
| 2026-01-26 | Meisner Derek M | Officer | +Exercise | 15,085 | $1.85 | $27,907 |
| 2026-01-26 | Meisner Derek M | Officer | −Sell | 15,085 | $3.00 | $45,255 |
| 2026-01-23 | Meisner Derek M | Officer | −Sell | 5,633 | $1.90 | $10,703 |
| 2026-01-22 | Barton Russell | Officer | −Sell | 462 | $1.84 | $850 |
| 2026-01-22 | OConnell Daniel Joseph | Director,Officer | −Sell | 2,689 | $1.88 | $5,055 |
| 2026-01-22 | Zuga Matt | Officer | −Sell | 1,687 | $1.86 | $3,138 |
| 2026-01-22 | Siemers Eric | Officer | −Sell | 895 | $1.82 | $1,629 |
| 2026-01-22 | Meisner Derek M | Officer | −Sell | 1,054 | $1.84 | $1,939 |
| 2026-01-21 | Barton Russell | Officer | −Sell | 2,315 | $1.81 | $4,190 |
| 2026-01-21 | OConnell Daniel Joseph | Director,Officer | −Sell | 9,346 | $1.81 | $16,916 |
| 2026-01-21 | Zuga Matt | Officer | −Sell | 2,473 | $1.81 | $4,476 |
| 2026-01-21 | Siemers Eric | Officer | −Sell | 2,331 | $1.80 | $4,196 |
| 2026-01-21 | Meisner Derek M | Officer | −Sell | 2,247 | $1.81 | $4,067 |
| 2026-01-20 | OConnell Daniel Joseph | Director,Officer | +Grant | 299,800 | — | — |
| 2026-01-16 | Doherty James J. | Officer | +Grant | 166,867 | — | — |
| 2026-01-16 | Schacterle Amy | Officer | +Grant | 84,600 | — | — |
| 2026-01-16 | Barton Russell | Officer | +Grant | 84,600 | — | — |
| 2026-01-16 | Siemers Eric | Officer | +Grant | 99,133 | — | — |
| 2026-01-16 | Meisner Derek M | Officer | +Grant | 99,133 | — | — |
| 2026-01-16 | Zuga Matt | Officer | +Grant | 99,133 | — | — |
| 2026-01-12 | OConnell Daniel Joseph | Director,Officer | −Sell | 5,388 | $1.73 | $9,321 |
| 2026-01-12 | Meisner Derek M | Officer | −Sell | 8,548 | $1.71 | $14,617 |
| 2026-01-09 | OConnell Daniel Joseph | Director,Officer | −Sell | 12,941 | $1.76 | $22,776 |
| 2026-01-09 | Meisner Derek M | Officer | −Sell | 5,200 | $1.76 | $9,152 |
| 2026-01-08 | Doherty James J. | Officer | −Sell | 6,467 | $1.82 | $11,770 |
| 2026-01-08 | OConnell Daniel Joseph | Director,Officer | −Sell | 8,143 | $1.82 | $14,820 |
| 2026-01-08 | Meisner Derek M | Officer | −Sell | 6,819 | $1.82 | $12,411 |
| 2026-01-08 | Meisner Derek M | Officer | −Sell | 30,092 | $1.82 | $54,767 |
| 2026-01-08 | Barton Russell | Officer | −Sell | 3,530 | $1.86 | $6,566 |
| 2026-01-08 | Zuga Matt | Officer | −Sell | 6,888 | $1.82 | $12,536 |
| 2026-01-07 | Barton Russell | Officer | −Sell | 1,700 | $1.99 | $3,383 |
| 2026-01-07 | Meisner Derek M | Officer | −Sell | 1,700 | $1.99 | $3,383 |
| 2026-01-07 | Meisner Derek M | Officer | −Sell | 10,070 | $1.99 | $20,039 |
| 2026-01-07 | OConnell Daniel Joseph | Director,Officer | −Sell | 37,755 | $1.99 | $75,132 |
| 2026-01-07 | Zuga Matt | Officer | −Sell | 1,700 | $1.99 | $3,383 |
| 2026-01-07 | Zuga Matt | Officer | −Sell | 4,105 | $2.00 | $8,210 |
| 2026-01-07 | Schacterle Amy | Officer | −Sell | 1,097 | $1.98 | $2,172 |
| 2026-01-07 | Doherty James J. | Officer | −Sell | 1,700 | $1.99 | $3,383 |
| 2026-01-06 | Barton Russell | Officer | −Sell | 3,618 | $1.97 | $7,127 |
| 2026-01-06 | Meisner Derek M | Officer | −Sell | 3,801 | $1.97 | $7,488 |
| 2026-01-06 | Meisner Derek M | Officer | −Sell | 7,097 | $1.97 | $13,981 |
| 2026-01-06 | OConnell Daniel Joseph | Director,Officer | −Sell | 5,102 | $1.97 | $10,051 |
| 2026-01-06 | Siemers Eric | Officer | −Sell | 6,834 | $1.97 | $13,463 |
| 2026-01-06 | Zuga Matt | Officer | −Sell | 5,100 | $1.97 | $10,047 |
| 2026-01-05 | Barton Russell | Officer | −Sell | 4,000 | $1.96 | $7,840 |
| 2026-01-05 | Meisner Derek M | Officer | −Sell | 4,000 | $1.96 | $7,840 |
| 2026-01-05 | OConnell Daniel Joseph | Director,Officer | −Sell | 4,649 | $1.97 | $9,159 |
| 2026-01-05 | Siemers Eric | Officer | −Sell | 4,000 | $1.96 | $7,840 |
| 2026-01-05 | Zuga Matt | Officer | −Sell | 4,000 | $1.96 | $7,840 |
| 2025-06-04 | Porter Derrell | Director | +Grant | 12,800 | — | — |
| 2025-06-04 | Ives Jeffrey L. | Director | +Grant | 12,800 | — | — |
| 2025-06-04 | Fountain Nathan B | Director | +Grant | 12,800 | — | — |
| 2025-06-04 | Drapkin Kimberlee C | Director | +Grant | 12,800 | — | — |
| 2025-06-04 | Stalfort John A III | Director | +Grant | 12,800 | — | — |
| 2025-06-04 | Stoppel Laura | Director | +Grant | 12,800 | — | — |
| 2025-06-04 | RA Capital Healthcare Fund LP | Director,TenPercentOwner | +Grant | 12,800 | — | — |
| 2025-01-23 | Zuga Matt | Officer | −Sell | 28,902 | $1.72 | $49,711 |
| 2025-01-21 | Siemers Eric | Officer | −Sell | 3,219 | $1.59 | $5,118 |
| 2025-01-21 | Barton Russell | Officer | −Sell | 2,914 | $1.61 | $4,692 |
| 2025-01-21 | Meisner Derek M | Officer | −Sell | 3,418 | $1.59 | $5,435 |
| 2025-01-21 | OConnell Daniel Joseph | Director,Officer | −Sell | 12,619 | $1.59 | $20,064 |
| 2025-01-21 | Zuga Matt | Officer | −Sell | 4,364 | $1.60 | $6,982 |
| 2025-01-07 | OConnell Daniel Joseph | Director,Officer | +Grant | 225,400 | — | — |
| 2025-01-06 | Siemers Eric | Officer | +Grant | 66,800 | — | — |
| 2025-01-06 | Zuga Matt | Officer | +Grant | 66,800 | — | — |
| 2025-01-06 | Barton Russell | Officer | +Grant | 49,800 | — | — |
| 2025-01-06 | Meisner Derek M | Officer | +Grant | 66,800 | — | — |
| 2025-01-06 | Doherty James J. | Officer | +Grant | 62,600 | — | — |
| 2025-01-06 | Schacterle Amy | Officer | +Grant | 8,800 | — | — |
| 2025-01-03 | Siemers Eric | Officer | −Sell | 10,859 | $1.85 | $20,089 |
| 2025-01-03 | Zuga Matt | Officer | −Sell | 13,235 | $1.84 | $24,352 |
| 2025-01-03 | Barton Russell | Officer | −Sell | 7,636 | $1.86 | $14,203 |
| 2025-01-03 | Meisner Derek M | Officer | −Sell | 11,122 | $1.84 | $20,464 |
| 2025-01-03 | OConnell Daniel Joseph | Director,Officer | −Sell | 47,778 | $1.84 | $87,912 |
| 2024-01-19 | Meisner Derek M | Officer | −Sell | 8,933 | $3.48 | $31,087 |
| 2024-01-19 | OConnell Daniel Joseph | Director,Officer | −Sell | 15,200 | $3.47 | $52,744 |
| 2024-01-18 | Barton Russell | Officer | −Sell | 2,833 | $3.73 | $10,567 |
| 2024-01-18 | Siemers Eric | Officer | −Sell | 3,124 | $3.71 | $11,590 |
| 2024-01-18 | Zuga Matt | Officer | −Sell | 4,242 | $3.71 | $15,738 |
| 2024-01-02 | OConnell Daniel Joseph | Director,Officer | +Grant | 401,000 | — | — |
| 2024-01-02 | Zuga Matt | Officer | +Grant | 106,000 | — | — |
| 2024-01-02 | Siemers Eric | Officer | +Grant | 94,000 | — | — |
| 2024-01-02 | Meisner Derek M | Officer | +Grant | 91,000 | — | — |
| 2024-01-02 | Barton Russell | Officer | +Grant | 73,000 | — | — |
| 2023-08-17 | Ives Jeffrey L. | Director | +Exercise | 2,800 | $1.19 | $3,332 |
| 2023-08-17 | Ives Jeffrey L. | Director | +Exercise | 39,149 | $0.72 | $28,187 |
| 2023-08-17 | Ives Jeffrey L. | Director | −Sell | 2,800 | $6.66 | $18,648 |
| 2023-08-17 | Ives Jeffrey L. | Director | −Sell | 39,149 | $6.48 | $253,686 |
| 2023-07-21 | RA CAPITAL MANAGEMENT, L.P. | Director,TenPercentOwner | +Buy | 5,161,290 | $7.75 | $40M |
| 2023-01-17 | Barton Russell | Officer | +Grant | 26,700 | — | — |
| 2023-01-17 | Meisner Derek M | Officer | +Grant | 26,800 | — | — |
| 2023-01-17 | OConnell Daniel Joseph | Director,Officer | +Grant | 114,000 | — | — |
| 2023-01-17 | Siemers Eric | Officer | +Grant | 26,700 | — | — |
| 2023-01-17 | Zuga Matt | Officer | +Grant | 33,500 | — | — |
| 2022-12-29 | Zuga Matt | Officer | +Exercise | 50,000 | $1.19 | $59,500 |
| 2021-11-30 | OConnell Daniel Joseph | Director,Officer | +Exercise | 1,118 | $4.47 | $4,997 |
| 2021-07-06 | Shah Rajeev M. | Director,TenPercentOwner | +Conversion | 588,850 | — | — |
| 2021-07-06 | Shah Rajeev M. | Director,TenPercentOwner | +Conversion | 6,122,557 | — | — |
| 2021-07-06 | Shah Rajeev M. | Director,TenPercentOwner | +Buy | 1,759,332 | $16.00 | $28M |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
